Polycyclic Compounds

Please enquire for more information about 2-(3-Methoxypropyl)-1,3-dioxoisoindoline-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Indoleacetic Acid is the most common and naturally occuring plant hormone in the auxin class of hormones. It effects cell elongation, cell division as well as plant growth and development.

Please enquire for more information about 7-Chloro-8-methyl-2-thien-2-ylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

1,3-Dipropyl-7-methylxanthine is a xanthine compound that is structurally related to caffeine. It has been shown to have an inhibitory effect on the production of reactive oxygen species and cytosolic calcium levels in primary cells, as well as a nonselective adenosine receptor antagonist activity. It has also been shown to antagonize the effects of adenosine receptors, p2 receptors, and p2y receptors. This drug is used for the treatment of basophilic leukemia.

4-Methoxy-1H-indazole is a synthetic chemical that can be synthesized from ketones and methanol. This chemical has been made in high yield by reacting methoxyacetone with toluene in tetrahydrofuran, followed by an anhydride reaction with ethyl ketone. The synthesis of this compound involves the use of a variety of organic solvents and reagents, as well as the use of a variety of different techniques.

Please enquire for more information about N,N-Diethyl-N'-[(1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methyl]propane-1,3-diamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2,2'-Iminodiquinolin-8-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Quinoline derivative used in the preparation of compounds with anticonvulsant activity as well as compounds with potent antibacterial activity against gram-positive pathogens. References Guo, L. et al.: Eur. J. Med. Chem., 44, 954 (2009); Jarvest, R.L. et al.: J. Med. Chem., 45, 1959 (2002);

Please enquire for more information about 4-Chloro-N-(2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylbenzamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Bromo-7-bromoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Chloro-7-ethoxyquinoline-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Acetoxyindole is a configurational isomer of indole. It can exist in three possible forms: the cis form (3AIO), the trans form (3ATO), and the gauche form (3AGO). The cis and trans forms are enantiomers, which means that they have different properties. 3AIO has a configurational rotation of about 180°, whereas 3ATO does not. This difference leads to a difference in spectral properties as well, with 3AIO having distinct infrared and ultraviolet absorption bands. The gauche form has two rotational isomers, one with an axial orientation and one with a pseudoaxial orientation. This difference also leads to different spectral properties, but these are not as distinct as those seen for the other two configurations.

1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-isoquinoline is a chiral compound with two optical isomers. It is synthesized by the reaction of 1-(chloromethyl)isoquinoline with sodium methoxide in methanol. This product is used as a substrate for the synthesis of mivacurium chloride and borohydride reduction. It also has an important use in chemistry as a magnetic reagent.

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Please enquire for more information about N-(2-{1,4-Dioxa-8-azaspiro[4.5]decan-8-yl}-5-(propylcarbamoyl)phenyl)-2-oxo-2H-chromene-3-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Indole derivative, as antiviral and antitumor agent. References Borza, I., et al.: J. Med. Chem., 50, 901 (2007), Lefoix, M., et al.: Bioorg. Med. Chem., 16, 5303 (2008), Frost, J., et al.: J. Med. Chem., 51, 1904 (2008),

Please enquire for more information about 4-(4-Chlorophenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Bromoindole is a model compound that serves as a building block for the synthesis of pharmaceutically important compounds. 4-Bromoindole has been shown to have high catalytic rates for the oxidative coupling of zirconium oxide. This compound can also be used in asymmetric synthesis because it is able to form both R and S enantiomers in moderate yield. The reaction mechanism is thought to involve a nucleophilic attack by bromide on the carbonyl group, followed by elimination of hydrogen bromide from this intermediate. 4-Bromoindole can be synthesized in three ways: (1) via an oxidative coupling reaction with ZrOCl2 and H2O2; (2) via an oxidative coupling reaction with ZrOCl2 and HBr; or (3) by reacting 4-bromoaniline with CuSO4 and Mn(NO3)2.

Tetrahydroquinoline-3-carboxylic acid is a crystalline, water-soluble compound. It is an intermediate in the synthesis of l-phenylalanine, paraformaldehyde and formaldehyde. Tetrahydroquinoline-3-carboxylic acid can be hydrolyzed to produce formic acid and hydrogen chloride. This product is also optically active and can be used as an indicator for hydroiodic acid.

Please enquire for more information about (S)-2-Tetrahydroisoquinoline acetic acid hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2-Acetamido-6-chloro-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 137896-02-7) is a compound useful in organic synthesis. References Matsuda, A., et al.: J. Med. Chem., 35, 241 (1992),

Please enquire for more information about 2-(5-Chloro-2-hydroxyphenyl)-1H-isoindole-1,3(2H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about N-(2-Methylquinolin-6-yl)acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Formyl-5-methyl-1H-indole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications N-(2,6-Dichlorophenyl)isatin can be obtained from 2,6-Dichloroiodobenzene (D434690) which is a reactant in the synthesis of 3-(phenoxy-phenyl-methyl)-pyrrolidines as potent and balanced norepinephrine and serotonin reuptake inhibitors. Also an impurity of Diclofenac (D436465). References Van Orden, L.J., et. al.: Bioorg. Med. Chem. Lett., 23, 1456 (2013)

3-Quinuclidinone hydrochloride is an organic compound that is used as a reagent in organic synthesis. It is synthesized by the acylation of 3-quinuclidinol with ethyl bromoacetate in the presence of a base. This reaction occurs in an isolated yield, and the product can be purified by rotary evaporation. 3-Quinuclidinone hydrochloride has a high affinity for GABA receptors, which are found on nerve cells in the brain and inhibitory neurons throughout the body. The binding of 3-quinuclidinone hydrochloride to these receptors leads to a decrease in neuronal excitability. This drug also has been shown to have effects on motor function, including a positive effect on motor performance when tested using a rotarod test. The rate of this reaction can be increased by adding chloride or sodium carbonate as a catalyst and by increasing the reaction time. Substrate binding plays an important

1-Azatricyclo[3.3.1.1(3,7)]decan-4-one is a synthetic compound with the chemical formula C12H17NOS that has been shown to act as a selective 5HT3 antagonist, which blocks serotonin from binding to the receptor site and thereby prevents it from activating the receptor. It is an example of a non-steroidal anti-inflammatory drug (NSAID). This drug has demonstrated significant antinociceptive properties in animal models of pain. 1-Azatricyclo[3.3.1.1(3,7)]decan-4-one also has been shown to have antihistamine and sedative effects in animal models and may be useful for treating allergic reactions and insomnia, respectively.

Please enquire for more information about 1,3,4a,5,9b-Hexahydro,ethylester,2H-pyrido[4,3-b]indole-2-carboxylicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl rel-(1R,5S,6S)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Vinyl-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (RIS) is a neuroleptic drug that belongs to the class of phenothiazine. RIS is used for the treatment of schizophrenia and other psychotic disorders. The chemical synthesis process of RIS involves a four step sequence: 1) Nucleophilic substitution of 3,5 dimethoxyphenylacetonitrile with methyl iodide in an inert solvent such as tetrahydrofuran; 2) Protection of the reactive amino group by forming an acetal with ethylene glycol; 3) Alkylation of the acetal with propargyl bromide in the presence of a base such as sodium hydride; 4) Hydrolysis and decarboxylation of the resulting compound.

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7-(Trifluoromethyl)quinoline is a synthetic compound that has been used as an antimicrobial agent. It has been shown to be active against Gram-positive bacteria and Gram-negative bacteria, including multidrug resistant strains. 7-(Trifluoromethyl)quinoline inhibits the synthesis of DNA by binding to the bacterial 50S ribosomal subunit, preventing the formation of mRNA and protein. The molecular docking analysis showed that it binds to two different sites on the ribosome. One site is located on the peptidyl transferase center domain and another site is located on the ribosomal RNA binding domain. 7-(Trifluoromethyl)quinoline also inhibits cellular uptake of this drug by inhibiting protein synthesis in eukaryotic cells.

Please enquire for more information about 1,7-Dimethyl-1H-indole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page