Polycyclic Compounds

Please enquire for more information about 1,7-Dimethyl-1H-indole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-[(4-Methyl-2-piperidin-1-ylquinolin-6-yl)amino]-4-oxobutanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about 2-(4-Ethylphenyl)-3-methylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (R)-Boc-4-amino-5-(3-indolyl)pentanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

6,7-Dimethoxyisoquinoline is an isoquinoline alkaloid that has shown antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Gram-negative bacteria such as Escherichia coli. It inhibits bacterial growth by preventing the formation of the ternary complex between GTPase, GTP and cAMP. 6,7-Dimethoxyisoquinoline also has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. This compound is derived from popowia (Populus) bark extract and is used in vitro studies on Popowia faecalis.

3-Methyl-3,8-diaza-bicyclo[3.2.1]octane dihydrochloride is a high quality reagent that is useful as an intermediate in the synthesis of complex compounds and as a reagent for fine chemicals. 3-Methyl-3,8-diaza-bicyclo[3.2.1]octane dihydrochloride can be used as a versatile building block in the synthesis of speciality chemicals and research chemicals. It can also be used to synthesize a variety of reaction components, such as amines, carboxylic acids, alcohols, amides, and nitriles.

Rac1,2,3,4-tetrahydroisoquinoline-3-methanol is a synthetic inhibitor of Rac1. It has affinity for the active site and steric bulk that is similar to other Rac1 inhibitors. It is not stereoselective, but because it is chiral, it can be used in conjunction with other drugs that are also chiral. Rac1,2,3,4-tetrahydroisoquinoline-3-methanol binds to the enzyme in a directionally selective way and interacts with the sequence of the active site. The methyl ester group on rac 1,2,3,4-tetrahydroisoquinoline-3-methanol enhances its hydrophilicity and enantiomeric purity.

Please enquire for more information about 10,11-Dihydro-N-(2-hydroxyethyl)-N-methyl-5H-pyrido[2,3-c][2]benzazepine-10-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-(1,2,3,4-Tetrahydroquinolin-8-yl)ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

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5,7-Difluoro-1H-indole is a metabolically stable, potent inhibitor of influenza A virus polymerase. It has been shown to be active in vivo against influenza A and B virus replication. The compound is undergoing clinical development for the treatment of influenza. 5,7-Difluoro-1H-indole inhibits the activity of the influenza virus polymerase by binding to the enzyme’s basic protein and blocking its active site. This prevents viral replication and can lead to therapeutic benefits in patients with influenza A or B infections.

Please enquire for more information about Ethyl-1H-indazole-6-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Thiophen-3-Yl-1H-Indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

The tetrahydropyran is an organic compound with the molecular formula CH3CH2CH2C(O)CH2OH. It is a colorless liquid that is soluble in water and polar organic solvents. The compound can be prepared by reacting acetonitrile with trimethyl borate: The reaction products of this process are among other things, 1,8-diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic acid methyl ester (DETPA). DETPA has been used as a neutralizing agent in the treatment of textile dyeing effluents and as a flow rate controller in metering pumps. Biological properties of DETPA include antipyretic properties and acid catalytic activity. One of the impurities found in DETPA is 3-(2'-hydroxyethoxy)propionic acid which can be removed by treatment

Please enquire for more information about 4-Fluoro-1H-indazole-6-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(3-Methylphenyl)-4-nitro-1H-isoindole-1,3(2H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Ethyl 6-Cyano-1H-indole-2-carboxylate is a chemical reagent used in the synthesis of benzofuran inhibitors for mitogen-activated protein kinase phosphatase-1. Applications towards diabetes, obesity and insulin-resistant metabolic disorders. Also a reagent in the preparation of platelet receptor glycoprotein (Gp) IIb/IIIa antagonists used as ati-thrombotic agents. References Lazo, J. et al.: Bioorg. Med. Chem., 14, 5643 (2006); Ono, S. et al.: Chem. Pharm. Bull.,

Please enquire for more information about 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

(1S,4S)-1,7,7-Trimethyl-3-(Trifluoroacetyl)Bicyclo[2.2.1]Heptan-2-One is a white solid with a melting point of -76.8°C and a boiling point of 265°C at 10 mm Hg. It has the following functional groups: particle, luminescent, lanthanide, stabilizer, ligand, voltammetry, thermally stable and has nmr spectra that show light emission and coordination chemistry. This compound is a sulfoxide but can also be considered to be a phosphine or an amine depending on its structural features. The compound's nature is dependent on the temperature and pressure as well as the solvent it is being dissolved in.>>END>>

Please enquire for more information about Isoquinolin-4-ylboronic acid, HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page

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7,8-Dihydroxy-4-methylcoumarin is a bioactive compound, specifically a derivative of coumarin. This compound is naturally derived from plant sources, where it acts as a metabolite in various biochemical pathways. Its chemical structure is characterized by the presence of two hydroxyl groups at the 7 and 8 positions, along with a methyl group at the 4 position of the coumarin core, contributing to its unique pharmacological profile. The mode of action of 7,8-Dihydroxy-4-methylcoumarin involves its antioxidant properties, scavenging free radicals and protecting cells from oxidative stress. Additionally, it exhibits enzyme inhibitory activities, targeting enzymes such as tyrosinase, which plays a crucial role in melanin synthesis. In terms of applications, 7,8-Dihydroxy-4-methylcoumarin is utilized in research focused on developing therapeutic agents for diseases linked to oxidative stress and enzyme dysregulation. It is also studied for its potential in dermatological formulations due to its impact on melanin production, highlighting its relevance in cosmetic and pharmaceutical industries. Research continues to explore its broader therapeutic potential, driven by its multifaceted pharmacological actions.

Please enquire for more information about 7-Methoxy-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Applications 6-(gamma,gamma-Dimethylallylamino)purine riboside hemihydrate

Please enquire for more information about 4,6-Dimethylquinolin-2(1H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Furil is a pharmaceutical preparation used for the treatment of metabolic disorders, such as hypertension and diabetes. Furil is an inhibitor of the enzyme acyl coenzyme A: diacylglycerol acyltransferase-2 (DGAT-2) which catalyses the formation of triacylglycerols from diacylglycerol and free fatty acids. Furil has been shown to have potent inhibitory activity against DGAT-2, with an IC50 value of 0.5 μM. Furil also inhibits the enzyme phosphodiesterase 4B (PDE4B), which plays a role in signal transduction and inflammation. Furil can be synthesized by reacting hydrogen chloride with 2-bromoacetophenone in a nonpolar solvent to form 2,4-dichlorobenzoyl chloride, followed by reaction with 3-furancarboxylic acid in methanol to produce furil. Furil

Please enquire for more information about 2-(4-Bromophenyl)-6-chloroquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(3-Bromo-2,2-dimethylpropyl)-1H-isoindole-1,3(2H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

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