Coumarins

7-Methylcoumarin with strong hepatoprotective activity.

Oxypeucedanin hydrate, also Prangolarin, is an antioxidant, antimutagenic, and inhibits carb metabolism enzymes.

5,7-Dihydroxycoumarin is a natural product isolated from the dichloromethane extract of the inflorescences of Macaranga triloba.

7-Demethylsuberosin (7-demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory

Fluorescent dye used in diagnostic culture media

MAO inhibitor; neuro-protective and cognitive enhancement effects

Osthenol: Natural, selective hMAO-A inhibitor with antitumor, antifungal, and antibacterial properties. Ki=0.26 μM.

7-BFC (7-Benzyloxy-4-(trifluoromethyl)coumarin) is a coumarin-like fluorescent substrate that is a cytochrome marker for the study of CYP subtypes.

Lactone

Phellopterin is a bioactive compound belonging to the class of furanocoumarins. It is extracted from various plants within the Apiaceae family, notably Angelica and Peucedanum species. These plants are found in diverse geographical regions and have been used in traditional medicine for centuries. The mechanism of action of phellopterin involves its ability to interact with multiple biological pathways. It is known to exhibit inhibitory effects on enzymes and has potential antioxidant properties. Additionally, phellopterin has demonstrated modulation of cellular signaling pathways, which may contribute to its therapeutic potential. Phellopterin is primarily investigated for its applications in pharmacology and medicine. Research suggests that it may have beneficial effects in treating inflammatory conditions, enhancing immune response, and exerting antitumor activities. It is also studied for its neuroprotective effects and potential role in managing neurodegenerative diseases. The compound’s ability to interact with various biomolecular targets makes it a subject of interest in the development of new therapeutic agents. As research progresses, the full spectrum of phellopterin's pharmacological effects continues to be unveiled, leading to its consideration in novel drug development and therapeutic strategies.

Lactone

Oxypeucedanin is a major coumarin aglycone that can be extracted from Ostericum koreanum, coumarin aglycones have demonstrated various pharmacological effects, including anti-proliferation, anti-inflammation, and anti-pain; based on transcriptional alteration and complicated modulation of MAPK signaling, might be underlying mechanisms responsible for the various pharmacological effects of oxypeucedanin.

Neobyakangelicol is a phytochemical compound, which is a natural product derived from various plant species. Its source is predominantly the roots of certain medicinal plants that are known for their array of bioactive constituents. The mode of action of Neobyakangelicol primarily involves interacting with specific biochemical pathways, potentially including modulation of enzyme activity or receptor binding, which could result in diverse pharmacological effects. The uses and applications of Neobyakangelicol are mainly centered around its potential therapeutic benefits. It has been the subject of research studies exploring its effects in various biological systems, often with a focus on its antioxidant, anti-inflammatory, or other modulatory roles within cellular processes. As such, it is a compound of interest in the field of drug discovery and development, particularly in the quest for new treatments for diseases that involve oxidative stress and inflammation. Additionally, its natural origin as a phytochemical adds a layer of interest for those investigating plant-derived compounds with possible health benefits.

Oxypeucedanin is a furanocoumarin compound, which is derived from various plant sources, most notably those in the Apiaceae family such as Peucedanum and Angelica species. It functions primarily as a photoreactive agent, capable of interacting with DNA under ultraviolet (UV) light through a process called photoactivation. Upon UV exposure, it forms covalent bonds with DNA, leading to cross-linking that can disrupt cellular functions. The biological activities of Oxypeucedanin make it relevant in a range of scientific research and potential therapeutic applications. It has been reported to exhibit antioxidant, anti-inflammatory, and antimicrobial properties, offering interest for further studies in pharmacology. Moreover, due to its DNA-interacting capabilities, it is a subject of research in photochemotherapy, particularly for skin conditions such as psoriasis and vitiligo. As with many such compounds, careful consideration of its effects and toxicological profile is critical in the exploration of its applications. Oxypeucedanin continues to be a topic of scientific investigation, exploring its multifaceted roles and potential benefits in human health and disease management.

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M04137 - 4-Methylumbelliferyl phosphate (free acid)

Nodakenetin displays the least irritant and least persistent reactions on mouse ears, and exhibits the least cytotoxic capacity against brine shrimp larvae.

7-Hydroxycoumarin-3-carboxylic acid SE labels peptides, nucleotides, carbs; it's an amine-reactive ester.

Capensin is an alkaloid-based compound, which is a naturally occurring chemical derived from specific plant sources known for producing bioactive molecules. Its mode of action involves interacting with cellular pathways to produce pharmacological effects, making it of particular interest in biochemical and medical research. Capensin's potential uses and applications span diverse therapeutic areas, including studies on its effects as a candidate for anti-inflammatory or neuroprotective agents. Current research is focused on its ability to modulate neurotransmitter systems and its interactions at the cellular level to uncover pathways and targets of therapeutic potential. While the exact mechanisms and clinical relevance are still under investigation, Capensin provides a promising avenue for developing new therapeutic interventions.

4-Hydroxycoumarin is a synthetic organic compound, which is a derivative of coumarin. This compound derives from a benzopyrone structure, specifically known as a precursor in the synthesis of various anticoagulant agents. Its mode of action involves the inhibition of the enzyme vitamin K epoxide reductase. This inhibition subsequently decreases the synthesis of active clotting factors II, VII, IX, and X by preventing the regeneration of reduced vitamin K. 4-Hydroxycoumarin and its derivatives have pivotal applications in the pharmaceutical sector, particularly in the creation of anticoagulant medications such as warfarin and other pharmaceuticals used to prevent and treat thromboembolic disorders. In addition to their clinical applications, these compounds are also involved in biochemical research exploring enzyme inhibition and coagulation pathways. By providing insight into the molecular interactions between 4-Hydroxycoumarin derivatives and their enzymatic targets, researchers can develop more effective anticoagulant therapies with improved safety profiles.

Fraxetin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM.

7-Ethoxycoumarin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Natural glycoside

6,7-Dimethylesculetin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fabiatrin is a natural product isolated and identified from n-butanol extract of Przewalskia tangutica.

1. Nodakenetin ((-)-Prangeferol) has clinical efficacy.

Oxypeucedanin hydrate is an antimutagenic agent, it has antioxidant activity, and exhibits carbohydrate metabolizing enzymes inhibitory effect.

Bergamottin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Praeruptorin C: an antioxidant, calcium antagonist, protects neurons, reduces vascular hypertrophy, affects cellular signals.

Epoxybergamottin is a furanocoumarin derivative, which is a natural bioactive compound. It is primarily sourced from citrus fruits, particularly grapefruit. The primary mode of action of epoxybergamottin is the inhibition of cytochrome P450 enzymes, specifically CYP3A4. This enzyme is a major player in the metabolism of many pharmaceuticals, and its inhibition can lead to increased bioavailability and prolonged effects of drugs metabolized by this pathway. The uses and applications of epoxybergamottin are primarily in pharmacokinetic studies. It serves as a tool for understanding drug interactions and metabolism, aiding in the development of safer pharmaceutical regimens. Epoxybergamottin is also used in research to explore the effects of dietary components on drug efficacy and safety, highlighting its significance in both drug development and nutritional science. By studying compounds like epoxybergamottin, scientists can better predict and manage potential adverse effects that may arise from the consumption of certain foods during drug therapy.

Suberosin: anti-inflammatory, anticoagulant, deters Aedes aegypti bites, potential mosquito larvicide.

Pteryxin is an alkaloid derivative, which is a natural product isolated primarily from certain plant species within the Apiaceae family. As a complex organic compound, it exhibits a range of biochemical interactions at the molecular level. The mode of action for Pteryxin primarily involves its ability to interact with specific enzymatic pathways and receptors, facilitating or inhibiting particular physiological processes. This biochemical interaction underlies its potential pharmacological effects, which are these products' primary focus of study. Pteryxin's applications are mainly in the biomedical and pharmaceutical research fields. It has garnered attention due to its potential antitumor, anti-inflammatory, and antimicrobial properties, making it a candidate for detailed study in drug development. Its complex structural chemistry also presents opportunities for synthetic modification, allowing for the exploration of structure-activity relationships. Researchers are particularly interested in these interactions to develop targeted therapies and better understand the functionality of alkaloid derivatives. The study of Pteryxin contributes to the broader understanding of natural compounds in therapeutic development, promising impactful advancements in medical science.

Anhydrobyankangelicin is a coumarin derivative, which is a specialized type of organic compound commonly found in the plant family Apiaceae. This compound is biosynthetically sourced from the roots of plants such as Angelica species, where it is observed in varying concentrations. Anhydrobyankangelicin operates through interactions with several biological pathways, including modulating calcium channels and inhibiting certain enzymes involved in oxidative stress. This mechanism of action contributes to its efficacy in providing neuroprotective effects. In scientific contexts, Anhydrobyankangelicin is primarily investigated for its potential therapeutic applications in neurodegenerative diseases. Its ability to influence multiple pathways at a cellular level makes it a compound of interest for mitigating cellular damage and reducing inflammation in neurological tissues. Current research explores its usage in experimental models of disorders like Alzheimer's and Parkinson's disease, aiming to elucidate its capability to protect neuronal cells and support cognitive function. Further studies are necessary to expand on its pharmacokinetics and optimize its application potential in clinical settings.