Polycyclic Aromatic Hydrocarbons (PAHs)

Stability Air Sensitive Applications 2-AMINOANTHRACENE (cas# 613-13-8) is a useful research chemical.

Applications Dibenz[a,h]anthracene is a polycyclic aromatic hydrocarbon (PAH) and a known carcinogen. Dibenz[a,h]anthracene has produced positive results in bacterial DNA damage and mutagenicity assays and in mammalian cell DNA damage, mutagenicity and cell transformation assays. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Farmer, P.B. et al.: Mutat. Res. Re. Mutat. Res., 544, 397 (2003); Leadon, S. et al.: Carcinogenesis, 16, 3021 (1995); Andrews, A.W. et al.: Mutat. Res., 51, 311 (1978); Kaden, D.A. et al.: Cancer Res., 39, 4152 (1979);

Applications Polycyclic aromatic hydrocarbons as carcinogenic agents. References Hansen, B., et al.: Environ. Toxicol. Chem., 18, 772 (1999), Czub, G., et al.: Environ. Sci. Technol., 38, 2406 (2004),

Stability Light Sensitive Applications A heterocyclic aromatic compound with potent mutagenic and carcinogenic properties. References Smith, C., et al.: Food Chem. Toxicol., 38, 637 (2000), Koehler, D., et al.: J. Ind. Ecol., 9, 143 (2005), Bartos, T., et al.: Env. Toxicol., 21, 343 (2006), Shimada, T., et al.: Chem. Res. Toxicol., 21, 2313 (2008),

Applications 9-Chlorofluorene is a monochlorinated fluorene with therapeutic effects on fungal diseases of tomato. 9-Chlorofluorene is part of a class of halogenated pollutants observed in the urban atmosphere. References Buchenauer, H. et al.: Phytopathol. Zeitsch., 72, 145 (1971); Buchenauer, H. et al.: Nature, 227, 1267 (1970); Ma, J. et al.: Environ. Sci. Technol., 43, 643 (2009);

Applications 2,7-Dibromophenanthrene is a halogenated phenanthrene (P294800), a polycyclic aromatic hydrocarbons and environmental pollutant. References Brown, W.G.,et al.: J. Am. Chem, Soc., 65, 1235 (1943); He, B.,et al.: J. Mat. Chem., 21, 14793 (2011);

Applications An active metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons found in hot mix asphalt paving workers. DBC is the most potent tumorigen that has been identified to date. Dibenzo[def,p]chrysene (DBC) is a carcinogen and should be handled with caution. References Anderson, L., et al.: Toxicol. Appl. Pharmacol., 199, 85 (2004), Yu, Z., et al.: Cancer Res., 66, 755 (2006), Shen, J., et al.: Toxicol. Sci., 95, 313 (2007),

Applications 3,5-Dichloroacenaphthene is a chlorinated derivative of Acenaphthene (D448330); a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. References Campbell, K., et al.: J. Org. Chem., 16, 1712 (1951); Reisen, F. & Arey J.: Env. Sci. Tech., 36, 4302 (2002)

Applications 4-Methylquinoline is used as a reagent in the synthesis of azetidine based ene-amides as potent bacterial enoyl ACP reductase inhibitors. Also used as a reagent in the synthesis of cyanine-styryl dyes with enhanced photostability for fluorescent DNA imaging. References Takhi, M., et al.: Eur. J. Med. Chem., 84, 382 (2014); Bohlaender, P.R., et al.: Org. Biomol. Chem., 11, 7458 (2013)

Applications 1-Acenaphthenol is a product of the microbial metabolism and photolysis of acenaphthene, of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. 1-Acenaphthenol is also a known substrate of dihydrodiol dehydrogenases. References Reyes, C., et al.: J. Photochem. Photobiol. A, 112, 277 (1998); Šavlík, M., et al.: Res. Vet. Sci., 83, 20 (2007); Schocken, M. & Gibson, D.: Appl. Environ. Microb., 48, 10 (1984);

Applications Benzo[a]pyrene-6,12-quinone is a polycyclic aromatic hydrocarbon (PAH) and metabolite of Benzopyrene (B205800) that can have toxic effects on fish bone metabolism. In utero exposure to Benzo[a]pyrene-6,12-quinone can also predispose offspring to cardiovascular dysfunction in later life. References Hayakawa, K., et al.: WIT Trans. Ecol. Envir., 135, 231 (2010); Jules, G.E., et al.: Toxicology, 295, 56 (2012)

Applications Clenpenterol was detected as a β-agonist residue in foodstuffs sourced from animal meats. References Shelver, W., et al.: J. Immunoassay, 21, 1 (2000), Smith, D., et al.: J. Anim. Sci., 80, 1240 (2002), Shelver, W., et al.: J. Agric. Food Chem., 51, 3715 (2003),

Applications 1,5,6-Trichloroacenaphthene is a chlorinated derivative of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. References Campbell, K., et al.: J. Org. Chem., 16, 1712 (1951); Reisen, F. & Arey J.: Env. Sci. Tech., 36, 4302 (2002)

Applications 2-Bromofluorene is used as a reagent for the preparation of dibromofluorene-labelled polystyrene by nitroxide-mediated polymerization. It is also being used in the agricultural sector as a fungicide for tomato disease control. It’s carcinogenic effects on humans are currently being investigated. References Buchenauer, H. & Grossmann, F.: Nature, 227, 1267 (1970); Butcher, W. & Tillman, E.: Macromol. Chem. Physic., 212, 2224 (2011); Wang, J., et al.: Environ. Sci. Technol., 46, 9745 (2012);

Applications Naphthacene is a polycyclic aromatic hydrocarbon. Naphthacene is often used as a molecular organic semiconductor in organic field-effect transistors and organic light-emitting diodes. Naphthacene is also used in various applications involving the enhancement of photocurrent. References Cnops, K., et al.: Applied. Phy. Letters., 101, 143301 (2012); Ooi, Z.E., Applied. Phy. Letters., 100, 93302 (2012);

Applications A reagent used to synthesize various dyes used in the textile industry. This is the labeled analog. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Rosenkranz, H.S. et al.: Mutagen., 5, 137 (1990);

Applications 1-Acenaphthenone is a product of the photolysis (and microbial metabolism) of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. References Kostoff, D.: Nature, 142, 753 (1938); Reyes, C., et al.: J. Photochem. Photobio. A, 112, 277 (1998); Schocken, M. & Gibson, D.: Appl. Environ. Microb., 48, 10 (1984)