Polycyclic Aromatic Hydrocarbons (PAHs)

Applications Acenaphthylene-d8 is labelled Acenaphthylene (A130750) which is a polycyclic aromatic hydrocarbons as carcinogenic agents. References Hansen, B., et al.: Environ. Toxicol. Chem., 18, 772 (1999), Czub, G., et al.: Environ. Sci. Technol., 38, 2406 (2004),

Applications Protected Naphthylamine. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Barbay, J., et al.: Bioorg. Med. Chem. Lett.,18, 2544 (2008), Konda, S., et al.: J. Chem. Pharm. Res., 2, 187 (2010),

Applications 6-Aminochrysene is a potent inhibitor of transferase activity. Also, it is used for the synthesis of diarylthiourea analogs as novel anti-cancer agents. References Liu, S., et al.: Bioorg. Med. Chem. Lett., 25, 1301-1305 (2015)

Stability Light Sensitive Applications An oxidative metabolite of Styrene (S687790). References Linhart, I. et al.: Chem. Res. Toxicol., 1, 251 (2010); Shen, S. et al.: Drug Metab. Disp., 38, 1934 (2010); Watabe, T. et al: Mutat. Res., 93, 45 (1982);

Applications 5-Chloroacenaphthenone is a chlorinated derivative of 1-Acenphthenone (A130755). 1-Acenaphthenone is a product of the photolysis (and microbial metabolism) of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. References Kostoff, D.: Nature, 142, 753 (1938); Reyes, C., et al.: J. Photochem. Photobio. A, 112, 277 (1998); Schocken, M. & Gibson, D.: Appl. Environ. Microb., 48, 10 (1984)

Applications 9H-Carbazole is a common component of complex electrical materials. Also an impurity in the synthesis of Carprofen (C184350), a non steroidal anti-inflammatory that is used by veterinarians for the relief of arthritic systems in dogs. It can be used for joint pain or post operative inflammation. Carprofen, is also used for the relief from pain and inflammation associated with osteoarthritis, hip dysplasia and other joint issues.Dyes and metabolites.This compound is a contaminant of emerging concern (CECs) References Percec, V. et al.: Nature, 419, 384 (2002); Randall, L.O., et al.: Arch. Int. Pharmacodyn., 220, 94 (1976), Yu, T.F., et al.: J. Clin. Pharmacol., 20, 347 (1980), O’Brien, W.M., et al.: Pharmacotherapy, 7, 16 (1987),

Applications 2-Nitronaphthalene has been used in the study for naphthalene-тАЛbased inhibitors of Trypanosoma brucei RNA Editing Ligase 1. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Durrant, J.D., et al.: PLOS Negl. Trop. Dis., 4 (2010)

Applications 1,2,6-Trimethylphenanthrene is a persistent organic pollutant (POP). References Bratberg, M., et al.: Chemosphere, 90, 2157 (2013)

Stability Light Sensitive, Volatile Applications Benzofuran is produced from coal tar. Found in tobacco smoke derived compounds, it is a carcinogen, seen to cause kidney damage. However it is also used in combination with phenolic antioxidants in meat curing. It has also recently been used in the synthesis of novel glutarimide antibiotics. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Kjallstrand, J. et al.: Food. Chem., 74, 85 (2001); Robbiano, L. et al.: Toxicol., 204, 187 (2004); Thelestam, M. et al.: Toxicol., 15, 203 (1980); Merck Index 14th ed. 1082; Kiyota, H. et al.: J. Pesticide Sci., 26, 93 (2001);