Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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Aβ-IN-1 TFA
Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.Formula:C37H50F3NO2Purity:100%Color and Shape:SoildMolecular weight:597.79SNX2112
CAS:SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.Formula:C23H27F3N4O3Purity:98.9% - 99.46%Color and Shape:SolidMolecular weight:464.48Ref: TM-T6305
1mg40.00€5mg85.00€10mg127.00€25mg220.00€50mg334.00€100mg477.00€200mg662.00€1mL*10mM (DMSO)87.00€CCT251236
CAS:CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.Formula:C32H32N4O5Purity:98.82% - 99.89%Color and Shape:SolidMolecular weight:552.62Ref: TM-T14905
1mg39.00€5mg116.00€10mg221.00€25mg457.00€50mg733.00€100mg1,111.00€200mg1,501.00€1mL*10mM (DMSO)144.00€Protein kinase inhibitor H-7 dihydrochloride
CAS:Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Formula:C14H19Cl2N3O2SPurity:99.54%Color and Shape:White Crystalline SolidMolecular weight:364.29Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Formula:C26H18ClN3O2Purity:98.40%Color and Shape:SolidMolecular weight:439.89Bisindolylmaleimide IV
CAS:Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)Formula:C20H13N3O2Purity:98.83%Color and Shape:Dark Red SolidMolecular weight:327.34Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formula:C27H41N9O7Purity:100% - 99.83%Color and Shape:SolidMolecular weight:603.67Arg-Gly-Asp-Ser
CAS:Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Formula:C15H27N7O8Purity:98.29%Color and Shape:SolidMolecular weight:433.421,2-Dimyristoyl-sn-glycerol
CAS:1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..Formula:C31H60O5Purity:99.49%Color and Shape:White Powder With LumpsMolecular weight:512.81PD180970
CAS:PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Formula:C21H15Cl2FN4OPurity:98.47%Color and Shape:SolidMolecular weight:429.27Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
CAS:Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and a synthetic α5β1 integrin ligand.Formula:C22H35N9O9Purity:98%Color and Shape:SolidMolecular weight:569.57PF-06651481-00
CAS:PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.Formula:C26H29Cl2N5O3Purity:97.57%Color and Shape:SolidMolecular weight:530.45SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formula:C15H14ClN3OSPurity:98%Color and Shape:SolidMolecular weight:319.81PLN-1474
CAS:PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.Formula:C24H37N3O4Purity:99.25%Color and Shape:SoildMolecular weight:431.57Ref: TM-T60101
1mg52.00€5mg111.00€10mg180.00€25mg305.00€50mg439.00€100mg612.00€1mL*10mM (DMSO)124.00€Cercosporin
CAS:Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).Formula:C29H26O10Purity:98%Color and Shape:SolidMolecular weight:534.51N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formula:C28H29N7OPurity:98.60%Color and Shape:Off-White To Pale-Yellow SolidMolecular weight:479.58Ref: TM-T11641
1mg92.00€5mg170.00€10mg319.00€25mg540.00€50mg777.00€100mg1,074.00€1mL*10mM (DMSO)178.00€Geldanamycin
CAS:Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.Formula:C29H40N2O9Purity:98.83% - 99.27%Color and Shape:Yellow To Orange PowderMolecular weight:560.64MAP4343
CAS:Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.Formula:C22H34O2Purity:99.32%Color and Shape:SolidMolecular weight:330.5E7820
CAS:E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Formula:C17H12N4O2SPurity:98.31% - 99.11%Color and Shape:SolidMolecular weight:336.37Ref: TM-T4435
1mg35.00€2mg52.00€5mg69.00€10mg88.00€25mg144.00€50mg210.00€100mg339.00€200mg502.00€1mL*10mM (DMSO)85.00€Iso-H7 dihydrochloride
CAS:Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Formula:C14H19Cl2N3O2SPurity:99.64%Color and Shape:White Crystalline SolidMolecular weight:364.29Ref: TM-T7501
2mg40.00€5mg52.00€10mg90.00€25mg138.00€50mg197.00€100mg293.00€200mg408.00€1mL*10mM (DMSO)66.00€FAK-IN-21
CAS:FAK-IN-21 (compound 9) is a FAK inhibitor with an IC50 value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.Formula:C22H22F2N8O3SColor and Shape:SolidMolecular weight:516.52KIF18A-IN-2
CAS:KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.Formula:C25H34N4O5S2Purity:99.05%Color and Shape:SolidMolecular weight:534.69Ref: TM-T60026
1mg74.00€5mg172.00€10mg245.00€25mg383.00€50mg507.00€100mg672.00€200mg910.00€1mL*10mM (DMSO)202.00€HSP70-IN-1
CAS:HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).Formula:C24H28N6O2SPurity:100%Color and Shape:SolidMolecular weight:464.58Ref: TM-T3487
1mg96.00€5mg227.00€10mg354.00€25mg620.00€50mg847.00€100mg1,169.00€1mL*10mM (DMSO)230.00€ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formula:C18H17N3O4SPurity:98.84% - 99.50%Color and Shape:SolidMolecular weight:371.41AKE-72
CAS:AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.Formula:C30H29F3N6OPurity:98.3%Color and Shape:SoildMolecular weight:546.59Radotinib
CAS:Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notablyFormula:C27H21F3N8OPurity:99.13% - 99.97%Color and Shape:SolidMolecular weight:530.5Col003
CAS:Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Formula:C14H11NO4Purity:98.67% - 99.03%Color and Shape:SolidMolecular weight:257.24Ref: TM-T10860
2mg47.00€5mg70.00€10mg107.00€25mg216.00€50mg350.00€100mg542.00€200mg778.00€500mg1,169.00€1mL*10mM (DMSO)70.00€CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurity:99.81%Color and Shape:SolidMolecular weight:355.82Ref: TM-T14943
1mg35.00€2mg48.00€5mg74.00€10mg97.00€25mg187.00€50mg331.00€100mg547.00€1mL*10mM (DMSO)82.00€D-64131
CAS:D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.Formula:C16H13NO2Purity:99.48% - 99.67%Color and Shape:SolidMolecular weight:251.28PKCε (85-92)
CAS:PKCε (85-92) is a biologically active peptide that functions as a specific activator of ε-PKC and induces MARCKS phosphorylation in wild-type cells, but doesFormula:C39H54N10O14Purity:98%Color and Shape:SolidMolecular weight:886.9Schaftoside
CAS:Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.Formula:C26H28O14Purity:100% - 99.32%Color and Shape:SolidMolecular weight:564.49Ref: TM-T3898
1mg42.00€5mg85.00€10mg111.00€25mg210.00€50mg311.00€100mg467.00€200mg653.00€1mL*10mM (DMSO)95.00€FAK-IN-12
FAK-IN-12 (Compound 12S) is a selective FAK inhibitor with an IC50 of 47 nM.Purity:98%Color and Shape:Odour SolidTR-14035
CAS:TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33Ref: TM-T5310
1mg52.00€5mg105.00€10mg170.00€25mg298.00€50mg430.00€100mg605.00€200mg815.00€1mL*10mM (DMSO)111.00€Go 6983
CAS:Go 6983 is a pan-PKC inhibitor targeting PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, exhibiting IC50 values of 7 nM, 7 nM, 6 nM, 10 nM, and 60 nM, respectively.Formula:C26H26N4O3Purity:98.41% - 99.04%Color and Shape:SolidMolecular weight:442.51Ref: TM-T6313
1mg43.00€2mg55.00€5mg84.00€10mg126.00€25mg245.00€50mg388.00€100mg563.00€1mL*10mM (DMSO)88.00€KHS 101
CAS:KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.Formula:C18H21N5SPurity:98.00%Color and Shape:SolidMolecular weight:339.46AKT-IN-18
AKT-IN-18, an Akt inhibitor, demonstrates an IC50 value of 69.45 μM in A549 cells, effectively impeding Akt activity.Formula:C19H14ClN5O2SPurity:98%Color and Shape:SolidMolecular weight:411.864-Isopropoxybenzoic acid
CAS:4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.Formula:C10H12O3Purity:98.58%Color and Shape:White To Off-White PowderMolecular weight:180.2
