Organic Halides

4-(4-Chlorophenyl)-1H-pyrazole is a pyrazole derivative that is used as an anti-cancer drug. It induces apoptosis in cancer cells by binding to the DNA and inhibiting RNA synthesis. 4-(4-Chlorophenyl)-1H-pyrazole has been shown to inhibit cell proliferation of HL60, BEL7402, and BGC823 cells with cytotoxic effects that are mediated by the generation of reactive oxygen species. This drug also has elemental analysis and can be used for the treatment of human leukemia, lymphoma, and breast cancer.

Please enquire for more information about 3-Chloro-4-(1H-imidazol-1-yl)aniline including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Bromopyridin-2-ol is an isomeric organic compound that belongs to the group of triphenylphosphanes. It has a crystal x-ray diffraction pattern with a space group of P21/c and unit cell dimensions of a = 20.7, b = 23.1, c = 25.8 Å, β = 98.4°. 6-Bromopyridin-2-ol has been shown to react with 3-bromo-5-hydroxypyridine in the presence of light and heat to form 2-(3,5-dibromopyridin)-6-(hydroxymethyl)pyridine and 2-(3,5-dibromopyridin)-6-(methyloxymethyl)pyridine. These reactions are catalyzed by copper (II) acetate in acetic acid solution at room temperature or by naphthyl chloride

2-Bromobenzonitrile is an organic compound with a molecular formula of C6H5BrN. It is a precursor to the quinazolinones, a class of drugs used to treat autoimmune diseases and coronary heart disease. This substrate molecule undergoes a palladium-catalyzed coupling reaction to form an aromatic ring. The light emission from this reaction can be seen in the reaction solution. Anhydrous sodium reacts with 2-bromobenzonitrile to produce nitrobenzene and hydrogen gas, which are then reacted with hydrochloric acid to produce salt and water vapor. The nitrogen atoms in 2-bromobenzonitrile are also used as reactants in reactions with halides such as bromine or chlorine, producing alkyl bromides or chlorides as products. In addition, 2-bromobenzonitrile can be used for the Suzuki coupling reaction.

N-(3-Chloropropyl)piperidineHydrochloride is a hydrochloric acid solution, which is an alkali and a strong base. It is used as a catalyst in organic syntheses by converting hexahydropyridine to tetrahydrofuran. Its reaction system includes triethylamine and an organic solvent such as tetrahydrofuran. The efficiency of the reaction depends on the condition of the reaction system, such as pH and temperature.

Methyl 6-bromo-3-hydroxypicolinate is a pharmacokinetic inhibitor that was designed to inhibit HIV integrase. It binds to the active site of the enzyme and inhibits its function, preventing the integration of viral DNA into host cell DNA. Methyl 6-bromo-3-hydroxypicolinate has shown affinity for the HIV integrase enzyme in vitro and in vivo, with IC50 values of 0.03 μM and 0.04 μM, respectively. The drug has shown excellent pharmacokinetic properties, which may be due to its divalent cation binding and receptor binding properties. Methyl 6-bromo-3-hydroxypicolinate also shows antagonist activity against HIV integrase by competing with ATP for binding to the enzyme's active site, leading to increased susceptibility to inhibitors such as 3TC (lamivudine).

Please enquire for more information about N-Phenyltetrahydro-2H-pyran-4-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Fluoro-2-(methylthio)phenylboronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (R)-2-(2-Chlorophenyl)pyrrolidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (2E)-N-(2-Fluorophenyl)-2-(hydroxyimino)acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (±)-trans-4-(3-Cyanophenyl)pyrrolidine-3-carboxylic acid hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (2E)-1-(2-Chlorophenyl)-3-(dimethylamino)prop-2-en-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-(5-Bromoacetamidylpentyl) acrylamide is employed in the synthesis of substrates used for nucleotide sequence determination, covalently linked to polymer coatings such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM). Polynucleotide-binding substrates find application as molecular arrays and flow cells.

Please enquire for more information about 2-Propoxy-5-(trifluoroMethyl)pyridine-3-boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page