Heterocycles with Sulphur (S)

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Sodium thiophenolate is a reactive chemical that belongs to the group of antimicrobial agents. It is used in the treatment of hepatitis, caused by viruses such as Hepatitis C and B. The basis for this use is the reaction between sodium thiophenolate and nucleophilic groups on the surface of viral particles. The reaction products are hydrochloric acid and alkanoic acid which are then excreted from the body.

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Please enquire for more information about N-Butyloxycarbonyl-3-[8-(imidazol-1-ylmethyl)tetralin-5-yl]-5-isobutylthiophene-2-sulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Dibenzothiophene is commonly used in microbial studies as a sole, organic sulfur and carbon source for growth. Research concerning the biodegradation of dibenzothiophene by different types of bacteria is a currently being carried out, as these bacteria have the ability to breakdown other harmful polycyclic hydrocarbons (PAH) as well. This may prove to be a very practical method in removing PAH’s from soils, sludge and crude oils. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bastiaens, L., et al.: Appl. Environ. Microb., 66, 1834 (2000); Gunam, I., et al.: J. Microbiol. Biotechn., 23, 473 (2013); Omori, T., et al.: Appl. Environ. Microb., 58, 911 (1992)

2-Thiophenesulfonyl chloride is a nucleophilic compound that reacts with electron rich groups such as hydroxyl and amino groups. It has shown anticancer activity in animal models and is being studied for the treatment of bowel disease, autoimmune diseases, and inflammatory bowel disease. 2-Thiophenesulfonyl chloride inhibits serine proteases by reacting with the active site cysteine or histidine residue. This reaction produces an acyl enzyme intermediate which can be hydrolyzed to regenerate the original enzyme or react with another molecule of 2-thiophenesulfonyl chloride to form an irreversible covalent bond. 2-Thiophenesulfonyl chloride also inhibits the ns3 protease and macrocyclic inhibitors, which are enzymes involved in inflammation and cancer metastasis.

Please enquire for more information about 2-{[3-Ethoxy-2-(ethoxycarbonyl)-3-oxoprop-1-en-1-yl]amino}-4-phenylthiophene-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

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2-Bromo-5-phenylthiophene is a halogen with the chemical formula of C6H3BrS. It has a melting point of -29°C and a boiling point of 277°C. 2-Bromo-5-phenylthiophene is soluble in diethyl ether and chloroform and reacts with magnesium to produce Grignard reagents. It can be used as a light emitting compound for organic light emitting diodes (OLEDs). 2-Bromo-5-phenylthiophene can also be used as an efficient reagent for converting alkenes to alkanes. The colorless liquid has an odor that ranges from sweet to aromatic, similar to benzene.

2-Methylthiophene-3-boronic acid (MTBA) is a boron compound used in organic synthesis. It is a nucleophile that reacts with electrophiles to form an addition product. MTBA is used in the protodeboronation reaction to convert 2-methylthiophene into 3-methylthiophene, which can be used for the synthesis of other chemicals. This compound can also be used to synthesize 3-methylthiophene from 3-methylthiophenol via the miyaura reaction. The lithiation and selective protodeboronation reactions are both efficient methods for converting 2-methylthiophene into 3-methylthiophene. The regioselective method selectively converts one of the two possible methyl groups into the desired product, while the regioisomeric method produces two different products from one reactant. Finally, 2-Methylthiophene-3-boronic acid can be

Please enquire for more information about 2-Amino-6-ethyl-N-(2-methoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Ethyl 3-amino-5-phenylthiophene-2-carboxylate is an ester of ethyl and acid ethyl. It is a colorless oily liquid with a sharp odor. Its major use is as a pharmaceutical intermediate for the production of antibiotics, such as tetracycline, erythromycin, and streptomycin. Ethyl 3-amino-5-phenylthiophene-2-carboxylate is also used in the manufacture of herbicides and pesticides and in the synthesis of dyes, perfumes, and other organic compounds.

2-Bromo-3-hexylthiophene is an organic compound that has a boiling point of 109.8°C and a melting point of -25°C. It is a colorless liquid with a pungent odor. This compound reacts with palladium complexes to form an unsymmetrical alkyl group at the 3 position on the thiophene ring. The reaction proceeds through a reductive elimination mechanism, forming an alcohol or acetate as the termination product. 2-Bromo-3-hexylthiophene can be used to synthesize monomers for the production of polymers and elastomers, such as polystyrene and styrene butadiene rubber (SBR). 2-Bromo-3-hexylthiophene is soluble in ethanol, acetone, ether, benzene, chloroform and carbon tetrachloride.

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Tetraphenylthiophene (TPT) is a molecule that has been shown to have anti-inflammatory properties. It reversibly oxidizes in the presence of hydrochloric acid, producing hydroxyl radicals and hydrogen peroxide. The hydroxyl radicals cause irreversible damage to proteins within cells, causing cell death. TPT has also been shown to inhibit the growth of tumor cells by inducing apoptosis and inhibiting the production of inflammatory molecules such as prostaglandin E2. TPT emits light when excited with UV light or other wavelengths. This emission can be enhanced by adding molybdenum ions to the compound.

Applications 1,3,2-Dioxathiolane 2,2-Dioxide is an alkylating agent with carcinogenic activty. References Van Duuren, B.L. et al.: J. Nat. Cancer Inst., 53, 695 (1974);

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3-(Trifluoromethyl)thiophenol is a methylating reagent that can be used for the synthesis of grignard reagents and phosphonates. It is also used as a methylating agent in organic synthesis and as an intermediate in the production of other compounds. 3-(Trifluoromethyl)thiophenol reacts with benzotrifluoride to form the corresponding trifluoromethylthiolate, which can then be reacted with chloride to give the corresponding chloromethylated compound. The reaction time for this reaction is dependent on temperature. Reaction of 3-(trifluoromethyl)thiophenol with thiosemicarbazide or disulfides gives methylated thiosemicarbazones or disulfides, respectively. This reagent also reacts with nucleophiles such as ammonia and hydroxide ion, leading to nucleophilic substitution reactions. 3

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Applications 2-Amino-4,5-dimethylthiophene-3-carbonitrile is a useful research chemical for organic synthesis and other chemical processes. References Rahman, K. M. M., et al.: Pakistan J. Sci. Ind. Res., 46, 95 (2003); Madhavi, K., et al.: Res. J. Pharm. Biol. Chem. Sci., 8, 387 (2017)

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2-(4-Methoxyphenyl)benzothiophene is a piperidin derivative that has been shown to have estrogenic activity. It was synthesized from 2-chlorobenzothiophene and 4-methoxyaniline. It has been used as a pharmaceutical formulation for the treatment of endometriosis, cancer, and Alzheimer's disease. 2-(4-Methoxyphenyl)benzothiophene has also been shown to be effective in preventing restenosis following angioplasty by inhibiting muscle cell proliferation. 2-(4-Methoxyphenyl)benzothiophene binds to the estrogen receptor alpha (ERα), which prevents it from binding with DNA, thereby preventing transcription and replication. This molecule also inhibits the enzymatic activity of acetylcysteine, which is an antioxidant that protects cells against oxidative damage by free radicals such as hydrogen peroxide or hydroxyl radical

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Tert-Butyl thiophen-2-ylcarbamate is a racemic, tertiary amine that has a crystal structure consisting of two dihedral chains. This compound is a carbamate with the formula CH3COOC2H5CS. The tert-butyl group is bound to the carbon atom adjacent to the carbonyl group and forms hydrogen bonds with the carbonyl oxygen and hydroxyl groups. The molecule is chiral, so it has two different structures: The first structure consists of a chain of five atoms, while the second structure consists of a chain of six atoms. Each carbon atom in the chain has three hydrogens bonded to it. There are two hydroxyl groups on one end of the molecule, which form hydrogen bonds with the tert-butyl group. There are also two hydrogen atoms on each end of the molecule that form hydrogen bonds with other parts of the molecule.

3-Bromothiophene-2-carbonitrile is a reactive electrophile that serves as an intermediate for the synthesis of heterocycles. It is prepared by reaction with triethyl orthoformate and methoxy in the presence of sulfur, followed by thermolysis. The structure activity relationship of this compound has been studied using decahydroisoquinoline and methoxy group as models. Electron distribution in the nucleus and electron affinity enhancements are observed when 3-bromothiophene-2-carbonitrile is conjugated to azides or distal groups.

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Benzo[b]thiophene-2-carboxylic acid is an organic compound that has been used to study cardiac hypertrophy. It is a benzo[b]thiophene-2-carboxylic acid, which is a subgroup of the thiophene family of compounds. The synthesis of this compound was accomplished by reacting 2-chloroacetyl chloride with 2,6-dichlorobenzothiophene in acetyl chloride at room temperature. Benzo[b]thiophene-2-carboxylic acid has been shown to inhibit the release of acetylcholine and cause chronic kidney disease in rats. This drug also acts as a molecular docking ligand for picolinic acid, an inhibitor of autoimmune diseases and cancer. In addition, it has been shown to have antiinflammatory properties by inhibiting prostaglandin synthesis and suppressing immune responses in vitro. The mechanism of action for this drug may involve α7

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Methyl 4-aminothiophene-3-carboxylate hydrochloride is a nucleoside analog that inhibits the activity of DNA polymerase. It has been used to study the mechanism of DNA replication and for visualization of mismatched bases during DNA replication. Methyl 4-aminothiophene-3-carboxylate hydrochloride has also been used as a fluorescent probe for nucleobases, and as an analogue to deoxyguanosine. This compound has been shown to be effective in probing guanine, nucleosides, and deoxyribonucleosides.

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5-Formyl-2-thiopheneboronic acid is a synthetic molecule that has been shown to be an effective electron microscope stabilizer. It is a boronate ester with a formyl group at the 2-position and a thiophene ring at the 5-position. The chloride in this molecule is used as a functional group, which can then react with other molecules to form new compounds. The functional theory of 5-formyl-2-thiopheneboronic acid includes its ability to form bonds with other molecules and its use as an inorganic base. The particle size of 5-formyl-2-thiopheneboronic acid is unsymmetrical, making it different from other molecules.

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6-Methoxybenzo[b]thiophene is a potent antiproliferative agent that inhibits the growth of cancer cells. It interacts with the polymerase, which is involved in DNA replication and transcription, leading to cell death. 6-Methoxybenzo[b]thiophene has been shown to inhibit the growth of carcinoma cells in vitro. It also inhibits the growth of other cancer cells by modifying cellular components such as sulfamate, which may be due to its interaction with nuclear receptors or apoptotic pathways. 6-Methoxybenzo[b]thiophene has been shown to induce death in various types of cancer cells and can also suppress tumorigenesis in vivo. This compound also has a pharmacophore that matches the size and shape of a small molecule that binds to DNA polymerase beta, suggesting that it may have similar activity at this enzyme.

3-(Bromomethyl)-2-chlorothiophene is a halogenated aromatic compound that is used as an antifungal agent. It is active against the fungus Candida albicans, which causes oral and vaginal infections. 3-(Bromomethyl)-2-chlorothiophene binds to the enzyme cytochrome P450 and inhibits its activity. This inhibition leads to an accumulation of substrate and production of reactive oxygen species (ROS), which causes cell damage. 3-(Bromomethyl)-2-chlorothiophene is soluble in ethyl acetate but insoluble in water, making it ideal for topical application.

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