Heterocycles with Sulphur (S)

Applications Methyl 5-chlorothiophene-2-carboxylate (cas# 35475-03-7) is a useful research chemical.

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Octyl-3,4-thiophenedicarboximide (OTDA) is a solvent with low toxicity and a high boiling point. It can be used as a diode, in the manufacture of chlorobenzene, or as a monomer for polyethylene. OTDA has been shown to be an acceptor for choline. OTDA also reacts with iodides, leading to photoluminescent compounds. OTDA is used in solar cells because it is able to absorb light energy from the sun and convert it into electrical energy. OTDA can also be used as an eutectic solvent with chloride or c-h bonds.

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1-Benzothiophene-5-carboxylic acid is an intermediate in the synthesis of a variety of heterocycles. It is used to synthesize indole and azidoacetate, which can be used for the synthesis of other compounds. 1-Benzothiophene-5-carboxylic acid is prepared by the reaction of ethyl azidoacetate with cyclohexanone followed by treatment with benzene in the presence of sodium hydroxide. The resultant product is hydrolyzed to 1-benzothiophene-5-carboxylic acid. The compound reacts with nitroethane and a base (e.g., potassium carbonate) to produce azidoacetate, which can be used as a precursor for other compounds.

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Please enquire for more information about Methyl 3-(morpholin-4-ylsulfonyl)thiophene-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Methyl 2-[(cyanoacetyl)amino]-5-[(dimethylamino)carbonyl]-4-methylthiophene-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Methyl 5-benzyl-2-[(cyanoacetyl)amino]thiophene-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Thiophene-3-methanol is a template molecule that has been used to prepare polymers. It can be used as an electrochemical data for the study of atomic orbitals, polymer films, and hydroxyl groups. Electropolymerization of monomers can be done at low concentrations to produce a thin film of polythiophene. The polymer film has been shown to have high UV absorption in the range of 200-350 nm and is also responsive to nucleophilic reactions. Toxicity studies on rats show that thiophene-3-methanol is not toxic at doses up to 2000 mg/kg body weight. Immobilized thiophene-3-methanol has been shown to be an excellent catalyst for NMR spectroscopy studies, which provides information about the structure and composition of molecules in solution.

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Ethyl 2-amino-4-(4-fluorophenyl)thiophene-3-carboxylate is a chemical compound used in the manufacture of tetraborate, which is an inorganic salt. It is also used to produce potassium chloride and sodium sulfamate. Ethyl 2-amino-4-(4-fluorophenyl)thiophene-3-carboxylate can be manufactured by reacting titanium with ethyl 4-(2,6,6-trimethylcyclohexanecarbonyl)phenylacetate and then reacting it with sodium sulfamic acid. This reaction produces titanium tetraisopropoxide and ethyl 2-(2,6,6,-trimethylcyclohexanecarbonyl)phenylamine. The ethyl 2-(2,6,6,-trimethylcyclohexanecarbonyl)phenylamine reacts with chlorine gas to produce

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2,8-Dimethyldibenzothiophene is a chemical compound that is used in industry as an intermediate to produce other chemicals. It can be found in the environment as a result of both natural and industrial processes. The main use of 2,8-dimethyldibenzothiophene is for desulfurization of naphthalene, which can be accomplished by reacting it with hydrogen at high temperatures. This process leads to the formation of biphenyl, which is also produced industrially. The analytical methods available to identify 2,8-dimethyldibenzothiophene are gas chromatography and mass spectrometry. 2,8-Dimethyldibenzothiophene reacts with oxygen or nitric acid to form dibenzo-p-dioxin and dibenzo-p-furan respectively. These compounds are toxic and carcinogenic substances that can cause severe environmental pollution if not properly disposed of.

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2,3-Dibromothiophene is a monomer that is used in the production of polymers. It has been found to be an effective cancer therapy agent and has been shown to have anti-inflammatory effects. 2,3-Dibromothiophene has been observed to inhibit the growth of cancer cells by blocking the synthesis of nicotinic acetylcholine at the nerve terminal. This process prevents the release of neurotransmitters from nerve terminals and reduces neuronal activity. 2,3-Dibromothiophene also inhibits immune system cells such as B cells and T cells, which may be due to its ability to inhibit protein synthesis. 2,3-Dibromothiophene can be synthesized by a palladium catalyzed cross-coupling reaction between an alkynyl group and an imine nitrogen. The reaction yield can be increased by including a nitrogen atom in one of the reactants. This product also exhibits fluorescence properties with

2-Amino-4-methylthiophene-3-carboxamide is a small molecule that is a potent inhibitor of the JAK2 kinase. This enzyme is associated with human fibrosis and has been shown to be involved in the development of liver fibrosis in rats. 2-Amino-4-methylthiophene-3-carboxamide inhibits the production of cytokines such as IL1α, IL6, and TNFα. It also blocks the activation of transcription factors such as NFκB, which are involved in inflammation. The compound has been shown to be orally active and has demonstrated efficacy in animal studies. Analogues have also been synthesized for this compound that show similar activity.

2-(Trifluoromethyl)thiophene is a heterobicyclic compound with a hydroxyl group on the 2-position. It is a halogenated aromatic compound with two functional groups, the hydroxyl group and the alkylthio group. 2-(Trifluoromethyl)thiophene binds to nicotinic acetylcholine receptor, which are found in autonomic ganglia, and blocks the binding of acetylcholine to these receptors. This blocks nerve signals that control heart rate, blood pressure, and breathing. The enzyme inhibitors may also have an effect on insulin resistance.

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Applications 3-Thiophenecarboxylic Acid was used as a lading compound for the development of a clinic useful D-amino acid inhibitor and have the potential to sever as active site proves to elucidate the structure-function relationships of D-amino acids. References Katane, M., et al.: J. Med. Chem., 56, 1894 (2013)

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3,4-Dimethoxythiophenol is a chemical compound that is used as a fluorescence probe to study biological functions in cells. It reacts with hydroxyl groups and other reactive sites on proteins, including sulfhydryl groups, thiols, and amines. 3,4-Dimethoxythiophenol has been shown to inhibit the viability of cancer cells (e.g., prostate cancer cells) by interfering with the function of dehydrogenase enzymes. 3,4-Dimethoxythiophenol also inhibits growth of microglia (cells that protect neurons) in vitro. This inhibition is due to the production of reactive oxygen species by the microglial cells. The chemical structure of this compound includes a hydroxyl group and two methoxy groups.

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