Heterocycles with Sulphur (S)

4-Methoxythiophene-3-carboxylic acid is a phosphonium compound that can be synthesized by the reaction of methylthiophene with deuterium. This compound is used in labelling studies to detect the presence of cyclisation, extrusion and pyrolysis reactions. It also has a variety of analogues that can be synthesized from methoxythiophene or heterocyclic compounds.

Ethyl 2-amino-4-(3,4-dimethoxyphenyl)thiophene-3-carboxylate is a nicotinic acetylcholine receptor (nAChR) antagonist that has been shown to have anti-cancer and anti-epileptic effects. It also has been shown to inhibit the polymerase chain reaction in tumor tissue and may act as a potential mechanism of action for cancer treatment. This drug is being studied as a nootropic agent, which could be due to its ability to increase contractility and granule cell activity in the cerebellum. The drug also inhibits neurotransmission through its allosteric inhibition of nAChRs on granule cells in the cerebellum.

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A raw material for use in pharma, dye and organic synthesis industries.

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Methyl 3-amino-5-bromo-thiophene-2-carboxylate is a synthetic compound that belongs to the group of carboxylic acids. It is used in organic chemistry for cross coupling reactions, such as Suzuki and Raupach-Hochstetter reactions. Methyl 3-amino-5-bromo-thiophene-2-carboxylate is particularly suitable for the synthesis of substituted carboxylic acids with high functional groups, such as fluoro-, chloro-, bromo-, cyano-, nitro-, and amide groups. This compound can be used as a fluorescent probe in liquid chromatography and has been shown to be effective in mediating the anion exchange of carboxylic acids.