Heterocycles with Oxygen (O)

Applications 5-Nitro-1-benzofuran is a chemical reagent used in the synthesis of internal alkynes. Also used in the preparation of anti-oxidants quinolines. References Lu, L. et al.: Eur. J. Org. Chem., 2013, 1644 (2013); Kuzmin, V. et al.: Russ. Chem. Bull., 57, 2405 (2008);

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1,2,3,4,6,7,8-Heptachlorodibenzofuran is a polychlorinated dibenzofuran (PCDF) that has been found to be an environmental pollutant. This compound is used in the production of plastics and pesticides. It is also used as a catalyst for the conversion of hydrocarbons into other chemicals. It can be found in wastewater as a result of these processes. 1,2,3,4,6,7,8-Heptachlorodibenzofuran has shown potential to act as a proliferation inhibitor on cells in culture and may have immunosuppressive effects.

Applications 5-[3-(Trifluoromethoxy)phenyl-2-Furancarboxylic Acid is the structural analogue of 5-[2-(Trifluoromethoxy)phenyl]-2-furancarboxylic Acid (T790925), a reactant used in the preparation of (phenyl)-N-[(mercapto)(pyrrolyl)triazolyl]furancarboxamide and (phenoxy)-N-[(mercapto)(pyrrolyl)triazolyl]acetamide derivatives as herbicides. References Xue, S., Lu, C.: Youji Huaxue, 28, 1083 (2008)

5-Ethoxy-2(5H)-furanone is an oxidation product of 5-ethoxy-2(5H)-furanone. It has an isomeric, stereospecific, regiospecifically, and a tautomeric relationship with furfural. 5-Ethoxy-2(5H)-furanone can be produced by the oxidation of furfural with boron trifluoride etherate in the presence of iodosobenzene. The reaction mechanism involves the addition of hydrogen peroxide to the boron trifluoride etherate to form hydroperoxydiborane. This compound then reacts with iodosobenzene to produce 5-ethoxy-2(5H)-furanone and 2,5-dihydroxybenzaldehyde. The reaction produces a mixture of diastereomers that contain different numbers of carbon atoms due to the regiospecific

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Applications 2-((Tetrahydrofuran-2-yl)methoxy)phenoxy)tetrahydro-2H-pyran is an intermediate used in the synthesis of Bufetolol (B689435), a β-adrenergic blocking agent and it inhibits the activation of adenyl cyclase. References Ikegami, K., and Imamura, H.: Yakugaku Zasshi 96, 614 (1976); Yamaji, A., et al.: Yakugaku Zasshi 105, 1179 (1985)

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Applications 1,3-Dihydro-1,3-dioxo-5-isobenzofurancarboxylic Acid is an analog of Trioctyl Trimellitate (T804400) which is a plasticizer that was evaluated for endocrine disrupting activities through estrogen receptor alpha binding assay.

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Xylyldibutylbenzofuranone is a stabilizer that is added to plastics to prevent the polymer from splitting into its constituent monomers. It has been shown to be an effective antioxidant, inhibiting the oxidation of polyvinyl chloride and polyethylene terephthalate plastics. Xylyldibutylbenzofuranone can be used in combination with phosphites, which form stable compounds with the stabilizer. These compounds are not allergenic or damaging to health, but may cause allergic reactions in sensitive individuals. The analytical method for determining the content of xylyldibutylbenzofuranone in a plastic material is based on its carboxylate group and functional groups. Xylyldibutylbenzofuranone does not damage the environment and has been shown to have antioxidant effects against ozone-induced oxidation of polystyrene.

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4,5,6-Trimethoxy-2-benzofuran-1(3H)-one is a metabolite of dehydrocholic acid. It has been shown to have pharmacological activity in pharmacological tests and the demethylation of syringic acid. The pharmacological activities of 4,5,6-Trimethoxy-2-benzofuran-1(3H)-one are similar to those of syringic acid and formaldehyde. This metabolite is produced by the demethylation of syringic acid, which may be due to the presence of formaldehyde or other unidentified compounds.

Furancarboxaldehyde is a molecule with a heterocyclic ring. The molecule has an isomeric form, in which the two rings are not identical. Furancarboxaldehyde can be made by reacting acetoacetate and chlorides in the presence of nitrosyl chloride to yield the desired product. It can also be made by reacting furfural and acid chlorides in the presence of nitrogen gas to yield the desired product. Furancarboxaldehyde is an isomer of 5-(4-chlorophenyl)-2-furancarboxaldehyde, which differs from it only in that its conformation has been changed so that a proton on one of its carbons is replaced with a tetrahydropyrimidinone group.

3-Acetyl-3-methyldihydrofuran-2(3H)-one (AMF) is a monofunctional, acidic initiator that is used in polymerization reactions. It is a fast and efficient catalyst for polymerization reactions, which can be initiated with peroxides or hydroperoxides. AMF has been used in crosslinking reactions to produce polymers with desirable properties such as high heat resistance and flame retardancy.

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Stability Moisture Sensitive Applications 4,7-dimethyl-1,3-dihydro-2-benzofuran-1,3-dione (cas# 5463-50-3) is a useful research chemical.

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7-Hydroxybenzofuran is an organic solvent that is used as a reagent in the synthesis of carbofuran, a pesticide. 7-Hydroxydihydrobenzofuran is also used as a precursor to other organic compounds such as diazonium salts, hydrogen bonds, and acid catalysts. It has low energy with a chloride ion, which forms a hydrogen bond with the functional groups on the organic molecule. The acid catalyst then converts it into an acidic solution. This process can be carried out at room temperature or heated to higher temperatures. When heated, thermally activated reactions take place and isobutyraldehyde becomes dehydrated to form magnesium oxide and aluminium oxide.

3-Iodotetrahydrofuran is a stereoselective synthesis of 3-iodo-2,2,3,3-tetrafluoropropane. The reaction involves the use of anhydrous acetonitrile as a solvent and intermolecular hydrogen bonding to yield the desired product. 3-Iodotetrahydrofuran has been shown to inhibit the protease activity of human immunodeficiency virus (HIV) and may be useful in treating hepatic steatosis. It also has been shown to inhibit insulin resistance due to its ability to inhibit the chemokine receptor CXCR4. 3-Iodotetrahydrofuran is not currently approved for use in humans or animals.

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(R,R)-3,4-Dihydroxytetrahydrofuran is a carbon compound with the chemical formula C4H8O2. It is a tetritol and is formed by the elimination of two water molecules from two molecules of glycerol. The (R,R)-form has an asymmetric carbon atom that can be analyzed through an argon gas-based technique called high-temperature gas chromatography. The analytical results will show the reaction products of this elimination process and the temperatures at which they are formed. This compound has been shown to react with alditol under dehydration conditions to form alpha-hydroxylated ketones, which are often used in chemical structures for intramolecular reactions.

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2-(Isothiocyanatomethyl)tetrahydrofuran is a nitro compound that has been shown to inhibit the growth of neutrophils and other white blood cells. It inhibits the production of inflammatory compounds such as leukotrienes, prostaglandins, and lipoxygenase products by inhibiting cyclooxygenase-1 and 2 enzymes. 2-(Isothiocyanatomethyl)tetrahydrofuran also inhibits the growth of cancer cells through its interactions with CB1 receptors, which are located on the surface of cancer cells. This interaction prevents the activation of protein kinase C and phospholipase A2, which leads to decreased levels of arachidonic acid in cancer cells. This results in reduced cell proliferation and increased apoptosis (cell death).

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Applications 3-Furanmethanol (cas# 4412-91-3) is a useful research chemical.

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5-Hydroxy-4-Methyl 2(5H) furanone is an organic solvent that can be used as a byproduct of the reaction between alkali metal and dimethylformamide. It can also be generated by catalytic isomerization of methyl 2-furoate with hydrochloric acid, yielding enolate. This compound has been shown to have high yield in the conversion of 13-cis-retinoic acid into its corresponding trans isomer. 5-Hydroxy-4-Methyl 2(5H) furanone can be used as a reactant for lipase enzymes.

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2-(Isocyanatomethyl)furan is a reactive and irreversible covalent compound. It has been used in the treatment of cancer cells, as well as in the study of nervous system diseases.

2-Methylfuran is a compound that has been used as a catalyst in the synthesis of 2-methylpentane. The presence of nitrogen atoms in the molecule gives it some synergic effect with other catalysts, such as palladium and nickel. 2-Methylfuran can be detected at sensitivities of 10 parts per billion. A kinetic energy of ˜400 kJ/mole and a hydroxyl group give this compound the ability to react with laminar tissue culture cells. 2-Methylfuran is also a solid catalyst for methyl ethyl ketones, which are used in the production of solvents, plastics, and pharmaceuticals. Its transport properties are similar to those of isooctane, making it useful for studies on gas chromatography analysis.

Applications 2-Ethylfuran is a substance used in the studies on variations of essentials oils from leaves of Jasminum nudiflorum Lindl for medicinal purposes Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Jin, H., et al.: Anhui Nongye Kexue, 40, 10078 (2012)

1-(3,5-Dimethyl-2-Furanyl)-Ethanone is a natural compound that is an extracellular metabolite. It has been shown to stimulate the immune system and may be useful as a dietary supplement. 1-(3,5-Dimethyl-2-Furanyl)-Ethanone is also used in analytical methods for the determination of aldehydes and organic acids. The compound can be used to identify cancer cells by profiling the gene expression patterns of these cells. This metabolite also has regulatory function and can be used in functionalizing materials.

1-(3-Amino-1-benzofuran-2-yl)ethanone is a reactive, monomeric molecule that has the potential to form hydrogen bonds and coordinate covalent bonds with other molecules. 1-(3-Amino-1-benzofuran-2-yl)ethanone can form resonance structures, which are a set of electron density distributions that correspond to the same molecular geometry but differ in the distribution of electrons. The molecule has been shown to react with chloride ions. It is also possible for this molecule to undergo a transfer reaction by donating a hydrogen atom. The molecular electrostatic potential of 1-(3-Amino-1-benzofuran-2-yl)ethanone indicates that it is chemically active and can be found in benzothiophenes and phenacyl groups.

5,5-Dimethyldihydrofuran-2-one is a molecule that is found in nature and has been studied extensively because of its potential use as an anticancer drug. It has been shown to inhibit the growth of prostate cancer cells but not normal cells. The most common type of cancer cell death induced by 5,5-dimethyldihydrofuran-2-one is apoptosis. This molecule also inhibits the production of epoxides and hydroxyl groups, which are important for cellular metabolism. 5,5-Dimethyldihydrofuran-2-one can be used as a pheromone for insects and is often used as a starting material for the synthesis of other molecules. The reaction products of 5,5-dimethyldihydrofuran-2-one are biodegradable and degradable.

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2,5-Diphenylfuran is a nutrient solution that is used to treat skin cancer. It has high values of calcium binding and surface methodology. 2,5-Diphenylfuran also shows significant cytotoxicity in cells and polypeptides. The reactive groups on the molecule are methyl ethyl, glycol ester, and histological analysis. Body mass index can be an indicator of how this drug will affect a person's weight.

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2,3-Dihydro-2,2-dimethyl-7-hydroxybenzofuran is a human metabolite of carbofuran and has been shown to be an inhibitor of acetylcholinesterase. The bacterial strain CECT 4384 was used to produce the monoclonal antibody against 2,3-dihydro-2,2-dimethyl-7-hydroxybenzofuran. The monoclonal antibody was then purified by a technique called hybridoma cell line. This technique is a way to purify antibodies that are produced by hybridoma cells. It involves incubating the antibodies with an antigen such as 2,3-dihydro-2,2-dimethyl-7-hydroxybenzofuran in order to bind it and remove it from the solution. When the antibody binds to the antigen, it changes its shape and can be removed from the solution with a magnet or other device

2-Ethylbenzofuran is a benzofuran derivative that has been shown to be a potent inhibitor of acid transport. It is effective in the treatment of gastric and duodenal ulcers, as well as hyperchloremic acidosis. 2-Ethylbenzofuran inhibits the action of calcium carbonate by binding to the active site on rat liver microsomes. This binding prevents the formation of an enzyme-inhibitor complex with polyvinyl chloride, which is required for dibutyl acylation reaction and acidolysis. The drug also blocks acid transporter activity, which may be due to its ability to induce demethylation and inhibit calcium carbonate from forming an enzyme-inhibitor complex with polyvinyl chloride.

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