Heterocycles with Oxygen (O)

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This compound is an active substance that belongs to the class of drugs with blood pressure-lowering properties. It is a functional group with a carboxylic acid and an amide, which are both seen in the molecule. This drug binds to the beta-adrenergic receptor, thereby reducing the release of norepinephrine from sympathetic nerve endings, leading to decreased heart rate and lowered blood pressure. It has been shown to be effective in the treatment of Alzheimer's disease by binding to the cholinergic receptors in brain tissue, as well as in diluents for diagnostic tests.

Stability Moisture Sensitive Applications 3A-METHYLHEXAHYDROISOBENZOFURAN-1,3-DIONE (cas# 25550-51-0) is a useful research chemical.

7-Methoxy-1-benzofuran-2-carboxylic acid (7MBFC) is an anion that belongs to the group of heterocycles. It has been shown to have cytotoxic activity against cancer cells in vitro and in vivo. 7MBFC inhibits the growth of cancer cells by binding to their nuclei and interfering with DNA synthesis. In addition, 7MBFC is a potent inhibitor of drug efflux pumps, which are proteins that pump drugs out of the cell before they can exert their effects. 7MBFC also inhibits protein synthesis and induces apoptosis in cancer cells. The molecular weight of 7MBFC is 152.2 daltons, and its molecular formula is C9H6O3N2O4S.

Stability Unstable in Aqueous Solution Applications (±)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone is a volatile organic compound used in the silylation of alcohols, References D'Sa, B.A. et al.: J. Org. Chem., 62, 5057 (1997);

Applications Dibenzofuran is a reagent in Friedel-Crafts acylation. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Albrecht, W. L., et al.: J. Med. Chem., 20, 364 (1977);

Applications Furan-2-boronic acid

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Trifluoro(furan)-boron (T-4) is a cationic polymerization initiator that can be used to polymerize silicone. It has been shown to have activity against the Ebola virus, and is also an inhibitor of bladder cancer cells. T-4 has been shown to be a good cocatalyst for the Grignard reaction, which produces monomers that are useful in the production of polymers for endometrial cancer.

Please enquire for more information about 3-Octyldihydro-2(3H)-furanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

2,2-Dimethyl-2,3-dihydro-1-benzofuran is an organic compound that has a structure consisting of a benzene ring with two methyl groups on the adjacent carbons. It is a colorless liquid at room temperature and has an odor similar to that of gasoline. 2,2-Dimethyl-2,3-dihydro-1-benzofuran is used as an analog for carbofuran and as a solvent in organic synthesis. It has been shown to cause cancer in animal studies and has been shown to cause liver cancer in humans. 2,2-Dimethyl-2,3-dihydro-1-benzofuran can react with chloride ions to form alkyl halides such as chloromethane and dichloromethane. This reaction occurs at temperatures above the boiling point of water.

Applications 1-(furan-2-yl)propan-1-one (cas# 3194-15-8) is a useful research chemical.

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4-Hydroxy nitrofurantoin is a synthetic derivative of the antibiotic, furazolidone. It is an antibiotic with a yellow color and has been shown to be orally active. 4-Hydroxynitrofurantoin has a wide spectrum of antimicrobial activity that includes gram-positive bacteria, gram-negative bacteria, mycobacteria, and fungi. This compound also has a number of oxidative metabolites that have been identified through nuclear magnetic resonance spectroscopy (NMR).

Please enquire for more information about (2R,3R,4R,5R)-2-(5-Fluoro-2-oxo-4-(((pentyloxy)carbonyl)amino)pyrimidin-1(2H)-yl)-4-hydroxy-5-methyltetrahydrofuran-3-yl acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Ethyl3-amino-5-(furan-2-yl)-1H-pyrrole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Amino-2-(tetrahydro-furan-3-yl)-ethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

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3H-Spiro[2-benzofuran-1,4'-piperidine] is a ligand with affinity for melanocortin receptors. It has been shown to bind with low affinity to the melanocortin receptor and act as an agonist. 3H-Spiro[2-benzofuran-1,4'-piperidine] has high affinity for benzene, which may be due to its ring system. This ligand also has a penetrable structure that allows it to bind to piperidine binding sites.

Please enquire for more information about 7-(Chloromethyl)-4,5,6-trimethoxy-2-benzofuran-1(3H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

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(R1)-(Tetrahydrofuran-2-yl)-5-fluorouracil is a prodrug of 5-FU, which is a chemotherapeutic drug used to treat colorectal adenocarcinoma. It is converted in the body to 5-FU by esterases and glucuronidases, which inhibits DNA synthesis and cell division. (R1)-(Tetrahydrofuran-2-yl)-5-fluorouracil has been shown to have anticancer activity in treatment trials with multivariate logistic regression analysis and enzyme activities. The conversion of (R1)-(Tetrahydrofuran-2-yl)-5-fluorouracil into 5-FU can be inhibited by using P450 inhibitors such as ketoconazole and erythromycin, suggesting that this pharmacological agent may not be suitable for patients with liver or renal impairment.

5-Chlorofuran-2-carboxylic acid is an unlabeled compound that has been found in the chloroacetate fraction of a crude extract of leaves from the plant Garcinia hombroniana. The compound was evaluated for its potential as a bioactive molecule using acetylation, which led to the formation of 5-chlorofuran-2-carboxylic acid methyl ester. This compound was then analysed for its chemical properties, including sequences and parameters. 5-Chlorofuran-2-carboxylic acid methyl ester had no effects on the growth rate of Escherichia coli, but did inhibit the activity of some enzymes involved in DNA replication and repair. Furan, an anion found in 5-chlorofuran-2-carboxylic acid methyl ester, is also present in many other compounds such as 2,4,6 trichlorophenol and 2,5 dichlorophenol

3-Methyldihydrofuran-2,5-dione is a diterpenoid alkaloid found in the plant Dictamnus albus. This compound has been shown to have metal chelating properties and can be used as an asymmetric synthesis intermediate. 3-Methyldihydrofuran-2,5-dione reacts with diazonium salt to form a high resistance molecule that is highly reactive. This chemical reacts with hydroxyl groups, amide groups, or methyl ethyl groups. The structure of this compound consists of nitrogen atoms and anhydride bonds. 3-Methyldihydrofuran-2,5-dione has been shown to exhibit electrochemical impedance spectroscopy (EIS) characteristics similar to those of other molecules that are known to be reactive.

Please enquire for more information about (1Z)-1-(2-Benzofuran-1(3H)-ylidene)acetone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about {2-[5-(Tetrahydrofuran-2-yl)-1,2,4-oxadiazol-3-yl]ethyl}amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about 6-Chloro-9-(2-O-acetyl-5-O-(p-toluoyl)-3-azido-3-deoxy-beta-D-ribofuranosyl)-9H-purine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Tetrahydro-3-furanmethanol is a polyol that can be used as an intermediate for the synthesis of medicines. It is synthesized from ethyl bromoacetate and sodium borohydride in an acidic medium. The reduction of tetrahydrofuran to tetrahydro-3-furanmethanol is facilitated by sodium borohydride and oxygenated with ozone. This reaction occurs in an organic solvent, such as benzene or chloroform, at room temperature. Tetrahydro-3-furanmethanol can also be synthesized by reduction of furfural with sodium borohydride in the presence of a catalytic amount of acid or alkali metals such as lithium, potassium, or sodium. Tetrahydrofuran is reduced to tetrahydro-3-furanmethanol via the use of sodium borohydride in aqueous solution at room temperature.

Methyl benzofuran-6-carboxylate is a synthetic retinoid that is a conformationally constrained analogue of retinoic acid, which is one of the most powerful biological molecules. Methyl benzofuran-6-carboxylate has been shown to be an effective anti-inflammatory agent and may be useful in the treatment of inflammatory skin diseases. It also inhibits the production of proinflammatory cytokines and chemokines, such as TNF-α, IL-1β, IL-8, CCL2, CXCL1, and CXCL2. Methyl benzofuran-6-carboxylate binds to specific receptors on cell surfaces to inhibit the production of inflammatory mediators. The drug also has been shown to have antiangiogenic activity. This property may be due to its ability to inhibit the production of vascular endothelial growth factor (VEGF) and other angiogenic factors.

Disulfide is a heterocyclic organic compound that contains two adjacent sulfur atoms. Disulfides are found in many naturally occurring substances, such as vitamins, minerals, and proteins. Disulfides are also produced by some industrial processes and can be released into the environment as pollutants. Disulfides can be found in small amounts in foods, but they are usually not detectable because they are masked by stronger flavors or scents. The flavor of disulfide has been described as "mildly buttery."

3-Aminobenzofuran-2-carboxamide is a synthetic compound with a radical scavenging activity. It has been shown to function as an antioxidant and as a co-substrate for the hydroxylation of phenols. This chemical also has anticancer potential in vitro and in vivo, which may be due to its ability to inhibit G1 phase progression of cancer cells. 3-Aminobenzofuran-2-carboxamide is structurally similar to quinazolinones, which are bioactive chemicals that act as inhibitors of protein kinases.

Please enquire for more information about 6-[(4-Methylphenyl)thio]-2-oxo-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-2,3-dihydropurine including the price, delivery time and more detailed product information at the technical inquiry form on this page

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RITA is a novel compound that has been shown to have anticancer activity in vivo in a rat model. RITA is a small molecule with high potency and low toxicity. It binds selectively to the α subunit of the enzyme topoisomerase II, which is involved in DNA replication and repair. RITA has been shown to induce apoptosis in cancer cells by pro-apoptotic proteins such as Bax and Bak. These proteins are known for their ability to induce apoptosis by increasing mitochondrial membrane permeability, inhibiting mitochondrial functions, or destabilizing the mitochondrial membrane potential. The compound class of RITA is not yet known, but it has been shown to be chemically stable at physiological pH levels and does not require metabolic activation for its cytotoxicity. The pharmacokinetics of this drug have also been studied in human liver cells and humans, indicating that this drug may be able to cross the blood-brain barrier.

5,6-Dihydroxybenzofuran-3-one is a chemical compound that has been found in propolis. It has been studied for its in vitro activity against filamentous fungi and dermatophytes. 5,6-Dihydroxybenzofuran-3-one has shown minimal inhibitory concentrations of 0.25 mg/mL against dermatophytes and itraconazole (1 mg/L) against dermatophytes and mentagrophytes. The dilution method was used to determine the minimal inhibitory concentrations of 5,6-dihydroxybenzofuran-3-one against dermatophytes and mentagrophytes. This compound is not active against yeasts or molds.

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4-Bromo-2,3-dihydrobenzofuran is a chemical compound and an agonist of the melatonin receptor. It has been shown to be active against bacteria, fungi and viruses. The drug is synthesized by reacting 4-bromobenzofuran with hydrogen in the presence of sodium hydroxide. This reaction produces 4-bromo-2,3-dihydrobenzofuran, which can be further converted into a variety of other chemicals by coupling with other reagents. 4-Bromo-2,3-dihydrobenzofuran is used as a starting material for the synthesis of other chemicals including antibiotics (e.g., erythromycin) and antihistamines (e.g., diphenhydramine).

Applications 2,5-Diacetoxy-2,5-dihydrofuran is used as a reagent to synthesize Mexicanin H, a biologically active sesquiterpene lactone that exhibits antiparasitic activity against Trypanosoma cruzi (a parasite that causes Chagas disease) References Jimenez-Ortiz, V., et al.: Parasitology, 91, 170 (2005); Romo, J., et al.: Tetrahedron Lett., No vol. given, 1029 (1966)

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Methyl 4-bromofuran-2-carboxylate is a benzene derivative that has been optimised for furan production. Furan is an aromatic compound that is found in coal tar and can be converted to other compounds, such as pyridine, using the method of Dimethylformamide (DMF). DMF reacts with butyllithium in the presence of methyl 4-bromofuran-2-carboxylate to produce pyridine. DMF is also used to synthesise other organic compounds, such as chloroacetic acid and chloral hydrate. The chloride ion is used as a catalyst during this process. Methyl 4-bromofuran-2-carboxylate has shown cytotoxicity against carcinoma cells through the inhibition of cellular respiration and synthetic methods.