Heterocycles with Oxygen (O)

Applications Used in the preparation of antifungal agents. References Del Poeta, M. et al.; Antimicrob. Agents Ch., 42, 2495 (1998)

2,3-Dihydro-6-methylthieno[2,3-c]furan is a synthetic compound that belongs to the group of n-propyl compounds. It is synthesized by the introduction of an acid in a tetrahydrothiophene ring. The synthesis can be done with or without the presence of nitrate ions. It also has two hydroxyl groups and four methyl groups. When synthesized with nitrate ions, impurities such as ethylbenzene, acetophenone, and propylene oxide may be formed. 2,3-Dihydro-6-methylthieno[2,3-c]furan is an analog of 2,5-dimethylthiophene and is used as a solvent in organic chemistry.

5-Cyano-1-benzofuran-2-ylboronic acid is an antibacterial agent that can be used to treat bacterial infections. One of the mechanisms by which this drug prevents bacterial growth is by binding to the enzyme Dihydrofolate reductase, which plays a role in DNA synthesis and replication. The compound also has a spectrum of activity against Gram positive and Gram negative bacteria. It is active against Bacillus anthracis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Yersinia pestis, Enterobacter cloacae, Salmonella typhi and Shigella dysenteriae. This agent is also capable of inhibiting the growth of Mycobacterium tuberculosis and Mycobacterium avium complex.

2,3,5-Trimethylfuran is a biofuel that has been shown to react with glyoxal in an optimal reaction. This compound is also used in clinical chemistry for the determination of paratuberculosis. A 2,3,5-Trimethylfuran profile can be generated by gas chromatography coupled with mass spectrometry and provides diagnostic information about this chemical. The activation energy for the reaction of 2,3,5-trimethylfuran with glyoxal is

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Stability Air Sensitive, Unstable in DMSO Applications 2,2-DIMETHYL-2,3-DIHYDRO-1-BENZOFURAN-5-THIOL (cas# 1248920-72-0) is a useful research chemical.

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Ethyl 3-aminobenzofuran-2-carboxylate is a decarboxylated pyridine derivative that has been shown to react with an aldoxime to form an unsymmetrical aldehyde. This reaction is catalyzed by acid and alkaline hydrolysis. It is also able to form benzothiophenes and benzofurans through the same reaction. Ethyl 3-aminobenzofuran-2-carboxylate can be used in the synthesis of many other organic compounds, including phenacyl, carboxylic acids, pyridines, and aryl halides.

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2,5-Dichlorofuran is an organic compound that is a non-polar and colorless liquid. It is used as a solvent for chemical reactions and in the production of other chemicals. 2,5-Dichlorofuran has been found to be expressed in women, but not in men. It has also been shown to play a role in gastrulation and placodes formation during early development. In adulthood, it can be used as an unrealistic thermally induced dithiolates that reacts with sulfide or trigeminal expansion. The dipole of this molecule is oriented towards the sulfide group due to its negative charge.

cis-Tetrahydrofuran-2,5-diyl)dimethanol is a catheter that has been shown to be damaging to tissue and amines. It can also be used as a chemotherapeutic agent. cis-Tetrahydrofuran-2,5-diyl)dimethanol is injected into the cerebrospinal fluid of rats and the optical properties are measured. This drug is eliminated through the kidneys and not in the liver or brain tissue. cis-Tetrahydrofuran-2,5-diyl)dimethanol is alkylated by dimethylamine to form an active metabolite that can cross the blood brain barrier more easily than its parent compound.

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