Heterocycles with Nitrogen (N)

4,6-Diiodo-2-methylpyrimidine is a compound that can be synthesized by the palladium-catalyzed desilylation of 2-methylpyrimidines. This chemical can be used in organic synthesis as a substrate for the palladium-catalyzed Suzuki reaction or Heck reaction to form 4,6-diiodo-1,3,5-triazine derivatives. The product has been shown to have antiinflammatory effects.

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5,6-Dimethylpyrazin-2-amine is an analgesic and antiinflammatory agent. It has been shown to inhibit prostaglandin synthesis by inhibiting the cyclooxygenase activity of COX-1 and COX-2 enzymes. Furthermore, 5,6-dimethylpyrazin-2-amine has been shown to enhance the antiinflammatory activity of indomethacin in carrageenan rat paw edema experiments. 5,6-Dimethylpyrazin-2-amine has also been shown to have a high affinity for COX enzyme assays and is an excellent candidate for research into new drugs that have antiinflammatory properties.

Applications 2,4,6-Tris(pentadecafluoroheptyl)-1,3,5-triazine (CAS# 21674-38-4) is an s-triazine derivative (T773008) and is used as a reference standard in mass spectroscopy for m/z ratios between 600-1600. References Aczel, T.; et al.: Anal. Chem., 40, 1917 (1968);

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

N-[4-(4,4-Bis(4-fluorophenyl)butyl)-3-carbamoyl-2,6-dichlorophenyl]piperazine-1 acetamide dihydrochloride (CAS: 91403-89-8) is a conjugate that is used to treat inflammatory bowel disease. It is an inhibitor of the enzyme fatty acid synthase, which converts acetyl coenzyme A and malonyl coenzyme A into fatty acids. N-[4-(4,4-Bis(4-fluorophenyl)butyl)-3-carbamoyl-2,6-dichlorophenyl]piperazine-1 acetamide dihydrochloride has been shown to be effective in the treatment of cancer and colitis.