Heterocycles with Nitrogen (N)

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1-Cyclopentylpiperidine is a white crystalline solid that is soluble in organic solvents. Its chemical formula is C5H11N. 1-Cyclopentylpiperidine belongs to the group of piperidines, which are compounds that contain a five-membered ring consisting of four carbon atoms and one nitrogen atom. The methyl groups on the compound's side chain can be converted to other functional groups by adding a methyl group or removing one. The product can be used as a catalyst for reactions involving amines, formamide, and formic acid with excellent selectivity. 1-Cyclopentylpiperidine has an atmospheric pressure boiling point of 613°C at 0.1 mmHg and a vapor pressure of 2 × 10−4 torr at 25°C.

1-Cyclopropylpiperidin-4-one is a prodrug that is converted to 1-cyclopropylpiperidin-4-ol in vivo. It has been shown to be effective against acute lung injury by inhibiting the production of inflammatory cytokines such as tumor necrosis factor-α (TNF-α). The deuterium isotope effect on protonation and amine reactivity has been investigated using aldehydes and an allylamine. This analog has also shown functionalities for enzyme preparations, which may be due to its ability to bind with proteins containing functional groups such as thiols, hydroxides, carboxylic acids, or alcohols.

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Imidazole-4-carboxaldehyde is a 4-formyl derivative of imidazole used in the preparation of C17,20-lyase inhibitor for the treatment of androgen-dependent prostate cancer. It is also used in the synthesis of other biologically active compounds such as antimalarial drugs, fabrication of colorimetric chemosensor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

5-Iodo-2,4-dimethoxypyrimidine is a chemical compound that can be used as a ligand for palladium. It is selective for alcohols and carbinols. The compound has been shown to catalyze the desilylation of organic halides and oxidized alcohols with high yields. 5-Iodo-2,4-dimethoxypyrimidine can also be used in the synthesis of carbohydrates and vinyl acetate. The yield of dehydrohalogenated products was found to be high when 5-iodo-2,4-dimethoxypyrimidine was used as a catalyst.

2-(Methylthio)pyrazine is an antibacterial agent that binds to the target site, which is an enzyme called DNA gyrase. 2-(Methylthio)pyrazine inhibits the growth of bacteria by causing a break in the DNA strand and prevents it from replicating. The inhibitory activity of 2-(methylthio)pyrazine has been shown in a number of bacterial strains, including Enterobacter aerogenes, Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Staphylococcus aureus and Salmonella enterica. The reaction solution was prepared by adding 0.1 mL of ligand (2-(methylthio)pyrazine), 0.5 mL of reaction solution (buffer solution), and 1 mL of nitrogen gas to a test tube with 5 mL of water at room temperature for 5 minutes. The linear regression analysis showed a positive correlation between concentration and inhibition rate.

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5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidine-7-thione is a research chemical with a complex molecular structure. It has been extensively studied for its potential applications in various fields. This compound has shown interactions with different substances such as l-arabinose, chondroitin sulfate, fatty acids, d-xylose, glutamate, cordyceps, methanol, histidine, d-tagatose, and e. cloacae. The compound exhibits inhibitory effects on certain enzymes and has been investigated as a potential inhibitor for various biological processes. It shows promise as an inhibitor of coumarin derivatives. Due to its unique structure and diverse interactions with different substances, this research chemical holds great potential for further exploration in the fields of biochemistry and pharmaceuticals.

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4-tert-Butoxycarbonylaminopiperidine-1,4-dicarboxylic acid monobenzyl ester is a synthetic compound that has been shown to have antibacterial activity. It is insoluble in water and slightly soluble in chloroform. This compound does not show any significant spectrum of activity against fungi, but is active against Gram-positive bacteria. The antibacterial activity of this compound may be due to its acidic nature and ability to form sulfoxides when it reacts with sulfur.

5-Bromo-2-phenylpyridine is an ancillary that has been used as a trimethyl to react with azobenzene, picolinic acid, and other electrophiles. It is also used in the Grignard reaction and cross-coupling reactions. 5-Bromo-2-phenylpyridine can be used to synthesize certain heterocycles such as pyrimidines, pyrazines, quinolones, and imidazoles. This compound reacts with halides in a photophysical reaction solution to produce the corresponding bromide or chloride. The efficiency of this transformation depends on the nature of both the substrate and the halogen.

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[(2R,3S,5R)-2-(Acetyloxymethyl)-5-[5-Fluoro-3-(3-Methylbenzoyl)-2,4-Dioxopyrimidin-1-Yl]Oxolan-3-Yl] Acetate is a prodrug that has been shown to be effective against cancer cells in vitro and in vivo. It is converted by deacetylation into the active form of the drug, [(2R,3S,5R)-2-(Acetyloxymethyl)-5-[5-Fluoro-3-(3-Methylbenzoyl)-2,4-Dioxopyrimidin-1-Yl]Oxolan]-3-Yl] Acetic Acid (TZPPA), which inhibits thymidine synthesis. TZPPA has been shown to be more potent than peplomycin for the treatment of muc