Hydrocarbon Building Blocks

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Used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Brightening agent used for copper electroplating

(1-Methylpiperidin-4-yl)methanol is a potent inhibitor of the kinases vegfr-2 and vesicular glutamate transporter 2 (vglut2). It is also active against human tumor xenografts. The inhibitory activity was determined to be due to its ability to bind and covalently modify tyrosine residues in the kinase domain. The inhibitory potency of (1-Methylpiperidin-4-yl)methanol was found to be constant, regardless of oxygenation status. This suggests that the inhibition is not due to the binding of oxygenated metabolites. In vitro experiments showed that it inhibits cellular proliferation by blocking protein synthesis and arresting cells at G1 phase. This drug has potential as an antitumor agent because it inhibits tumor growth without affecting normal tissue or causing significant toxicity in animal models.

2,2-Difluoroethanol is a chemical compound with the molecular formula C2H4F2O. It is a colorless liquid that has a distinctive odor and is highly flammable. 2,2-Difluoroethanol reacts in an electrophilic substitution reaction to replace chlorine atoms with hydrogen atoms from the ethyl formate molecule. This reaction can be described by the following equation: CH3COOC2H5 + Cl → CH3COOC2H5Cl The activation energy for this reaction is 17.6 kcal/mol and it requires a strong acid catalyst such as phosphorus pentachloride to proceed. The mechanism of the reaction has not been definitively determined, but it may involve an intramolecular hydrogen bond between the hydroxyl group of one ethyl formate molecule and the chlorine atom of another ethyl formate molecule. The yield of this product depends on many factors including temperature, pressure,

N-octane is mainly used as a solvent, fuel and as one of the standard values in octane rating scale. It is also used to prevent uneven burning of fuel in internal-combustion engines. Further, it acts as an antiknock agent for high compression engine fuels, lacquer diluents, blowing agent for foam rubber. In addition, it is used in rocket propellants and in azeotropic distillations. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2,3-Dichloro-1-propanol is a metabolic byproduct of chlorinated solvents. It has been shown to be toxic to mitochondria and can cause mitochondrial membrane potential disruption in rat liver cells. The chemical reacts with fatty acids to form a reactive carbonyl group that can react with the hydrogen bond of membrane phospholipids. This reaction disrupts the structure of the lipid bilayer, leading to mitochondrial degeneration. 2,3-Dichloro-1-propanol also reacts with glutathione and carbonic anhydrase, which leads to the formation of reactive intermediates that react with DNA or proteins. These reactions are responsible for the observed toxicity effects in animals.

4-Fluoro-1-butanol is a gaseous protonated fluorine compound. The proton is transferred from the hydrogen to the fluorine, resulting in an intramolecular hydrogen bond. 4-Fluoro-1-butanol has been shown to undergo conformational changes due to the substituent effects of other atoms on its molecules. This molecule has been shown to be able to orient itself in different ways, depending on the experimental parameters and conditions that are used. 4-Fluoro-1-butanol has also been shown to have a strong hydrogen bond with other molecules such as water, which may be due to its ability to form a stable H···O hydrogen bond with a strong donor atom (fluorine).

2,2-Dimethyl-1,3-dinitropropane is a skeleton that has been shown to react as a carbanion. It is an intermediate in the reaction mechanism of cyclopenta[b]pyridines with amines. The tautomeric form of this skeleton is 2,2-dimethyl-1,3-diazirine. This skeleton also catalyses the nitroalkane to nitrite ion reaction and stabilizes the synthons involved in the synthesis of cyclopentane rings.

Putrescine is a polyamine plant growth regulator affecting the synthesis of macromolecules. Promotes adventitious root formation. Precursor of spermidine.