Alcohols

Docosahexaenoyl ethanolamide is a cyclase inhibitor that has been shown to have anorexigenic effects in mice. This compound inhibits the synthesis of pro-inflammatory cytokines and chemokines, which may be due to its ability to block toll-like receptor signaling pathways. Docosahexaenoyl ethanolamide also has been shown to increase the activity of PPARα, which regulates lipid and glucose metabolism. The physiological function of docosahexaenoyl ethanolamide is not well understood and further research is needed.

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2-Trifluoromethyl-4-chloroquinoline is a heterocyclic compound that belongs to the group of quinolines. It has insulin-like growth factor activity and is an antimalarial drug. 2-Trifluoromethyl-4-chloroquinoline has been shown to inhibit cancer cell proliferation by binding to receptor tyrosine kinases, which are found in cancer cells. The mechanism of action for this drug may be due to its ability to interfere with the tyrosine kinase domain of the receptors, thereby blocking the phosphorylation of receptor tyrosine residues. The aromatic ring system in 2-Trifluoromethyl-4-chloroquinoline can also bind colchicine, a chemotherapeutic agent that inhibits mitosis and DNA synthesis in eukaryotic cells.

Isobornylcyclohexanol is an organic acid that can be used as a viscosity-increasing agent in aqueous compositions, such as detergent compositions. It is typically used in the form of its sodium salt. Isobornylcyclohexanol has been shown to have a particle size between 5 and 10 micrometers when prepared with cyclohexanol and fatty acids. The vaporizing point of this organic acid is approximately 140 degrees Celsius. When heated, it decomposes into cyclohexanone, carbon dioxide, water vapor, and hydrogen chloride. This product has a hydroxyl group and two hydrocarbon chains (i.e., divalent hydrocarbons). The molecular formula for isobornylcyclohexanol is C10H20O2.

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Impurity Trimetazidine EP impurity D Applications 2,3,4-Trimethoxybenzyl Alcohol is a trimethoxylated aromatic alcohol. 2,3,4-Trimethoxybenzyl Alcohol is an impurity of the anti-anginal drug Trimetazidine (T795610). References Medenica, M.B. et al.: J. Chrom. Sci., 46, 430 (2008);

3,4,5,6-Tetrabromophenolsulfonephthalein is a colorless organic compound that is used in the medical field as an indicator of renal function. It is used to measure the glomerular filtration rate and determine if the kidneys are functioning properly. 3,4,5,6-Tetrabromophenolsulfonephthalein binds to fatty acids in the bloodstream and is absorbed by cells. The chemical structure of this molecule causes it to be taken up by cells with a high rate of lipid content such as those found in the liver and kidney. This uptake can be visualized using a spectrophotometer or microscope. 3,4,5,6-Tetrabromophenolsulfonephthalein inhibits fatty acid uptake into cells through an unknown mechanism.

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1-Methyl-7-nitro-1,2,3,4-tetrahydro quinoline is an ionic liquid that is soluble in carbonate and dimethyl carbonate at optimum concentrations. It is used as a solvent for alkylation reactions catalyzed by ionic liquids. 1-Methyl-7-nitro-1,2,3,4-tetrahydro quinoline can be prepared by nitrating methyl 7 nitrobenzoate with nitric acid in the presence of acetic acid and heating the mixture to produce 1 methyl 7 nitro 1,2,3,4 tetrahydroquinoline. This reaction requires a catalyst such as oxalic acid or zinc chloride.

Applications 1-Nonadecanol (cas# 1454-84-8) is a useful research chemical.

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