Cyano-, Nitrile-

4-Aminobenzonitrile is a chemical compound that has been shown to be an antimicrobial agent. It has been found to be active against bacteria and fungi, such as Candida albicans and Aspergillus niger. 4-Aminobenzonitrile binds with epidermal growth factor (EGF) by intramolecular hydrogen bonding, which leads to the disruption of the protein's tertiary structure. The nitrogen atoms in this compound have been shown to react with water vapor at high temperatures, which results in the release of hydrogen gas. This reaction can be used for phase transition temperature studies. 4-Aminobenzonitrile also shows intermolecular hydrogen bonding with fatty acids, which causes the molecule to change its shape and protonation state. These changes affect its frequency shift and molecular modeling study results.

S25285 - Trimethylsilylacetonitrile

6-Cyano-2,2-dimethyl-2H-benzo-[b]-pyran is a hydrogen bond donor. It can be used as a catalyst for the synthesis of pharmaceutical drugs. 6-Cyano-2,2-dimethyl-2H-benzo-[b]-pyran can also be used as a linker in immobilized catalysts. The reaction rate of 6-cyano-2,2-dimethyl-2H benzo[b] pyran with epoxides is fast enough to be used in kinetic studies. Xray structures of the 6cDNBP/Ag(I) complex and 6cDNBP/Cu(I) complex have been determined.