Halogenated Compounds

Applications 4-CHLORO-3-NITROANISOLE (cas# 10298-80-3) is a useful research chemical.

Applications Octafluoro-4,4'-biphenol (cas# 2200-70-6) is a useful research chemical.

Applications 2-Chlorotetrahydro-2-oxo-2H-1,3,2-oxazaphosphorin is an intermediate in the synthesis of N-Dides(2-chloroethyl) N-(2-Hydroxyethyl),N-(2-ethoxyethyl) Cyclophosphamide (C984610) which is a derivative of Cyclophosphamide Monohydrate (C988580), a known human carcinogen that is widely used in cancer chemotherapy because it can cross-link DNA causing strand breakage and mutation. References Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999)

Applications 2-Fluoro-3-nitrobenzoic Acid is used in preparation of bifunctional Heterocycles and their use in targeted degrdn. of RAF polypeptides. References Crew, Andrew P., et al.: U.S. Pat. Appl. Publ., (2020);

Applications 1-Bromodecane-10,10,10-d3 (CAS# 284474-47-1) is a useful isotopically labeled research compound.

Applications 3-(4-Chlorophenyl)propan-1-ol is used in preparation of 2-Oxo-2H-chromene-3-carboxylic Acid Amide derivatives as Aldo-Keto reductase inhibitors. References Toyooka, N., et al.: Jpn. Kokai Tokkyo Koho, (2018);

Applications N-​[4-​Cyano-​3-​(trifluoromethyl)​phenyl]​-​2-​hydroxy-​2-​methylpropanamide is a useful research chemical.

Applications 2,5-Bis(2,2,2-trifluoroethoxy)-1,4-benzenedicarboxylic Acid is used in the synthesis of new fluorinated ethers of aromatic acids and diesters. References Ritter, J. C., et al.: From PCT Int. Appl. (2011), WO 2011028852 A2 20110310

Applications 1-Bromohexane-5,5,6,6,6-d5 is a useful isotopically labeled compound of 1-Bromohexane (B683950)

Applications 5-Chloro-3-[(methylamino)sulfonyl]-2-thiophenecarboxylic Acid is an intermediate in preparation of Lornoxicam. References Fan, W., et al.: Zhon. Yiy. Gon. Zaz., 33, 365-366 (2002);