Ethers

Applications Tetramethoxymethane has application within an electrolyte solution for the use of rechargeable lithium batteries. It has also been used as a reactant in the synthesis of novel anti-HIV-1 compounds. References Cadger, T.G. et al.: Proc. Electrochem. Soc., 88, 699 (1988); Kazmierski, W.M. et al.: J. Med. Chem., 54, 3756 (2011);

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3-Methoxyacrylic acid methyl ester is a synthetic monocarboxylic acid. It is used in the metathesis reactions of organic chemistry and can be synthesized by reacting hydrogen chloride with ethyl formate, propionate, or chloroformates. It is also used to produce other organic compounds. This compound has been shown to act as an inhibitor of the formation of reactive oxygen species and may be useful in the treatment of inflammatory conditions such as arthritis.

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N-Hydroxy-4-methoxybenzamide is a protonated form of hydroxybenzamide. It is used as an inhibitor of reductase that catalyzes the conversion of 3-hydroxybenzoic acid to 2,4-dihydroxyphenylacetic acid in the biosynthesis of ribonucleotides. N-Hydroxy-4-methoxybenzamide has been shown to inhibit leukemia cells in mice and inhibits the growth of mammalian cells. This compound also has a stereoselective mechanism of action, which means that it only affects one enantiomer (R or S) of the substrate. The biological activity is not fully understood, but may be due to its ability to form an anion with a negative charge.

3,5-Dichloro-2,6-dimethoxybenzoic acid (3,5-DCMB) is a drug that binds to the dopamine transporter. It is used as a radioligand in studies of the pharmacological and biochemical properties of the dopamine transporter. 3,5-DCMB has also been shown to bind to plasma proteins and membranes with an affinity that depends on its physicochemical properties. The drug has been used clinically in the treatment of Parkinson's disease, but it is not active against other diseases such as depression or schizophrenia. 3,5-DCMB is one of two enantiomers of dichloroethylbenzoic acid; it is an ethylene transport inhibitor and can be converted into ethylene oxide via reduction by alcohol dehydrogenase.

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2-Formyl-6-methoxypyridine is a synthetic serine protease inhibitor. It binds to the active site of serine proteases and inhibits their activity by blocking the catalytic triad (Ser, His, Asp). 2-Formyl-6-methoxypyridine has been shown to inhibit the release of inflammatory mediators in mast cells. This drug also inhibits cardiovascular diseases through its ability to reduce cholesterol levels and atherosclerotic plaque formation. The supramolecular complex between 2-formyl-6-methoxypyridine and ruthenium can be used as a fluorescent probe for electrochemical studies. 2-Formyl-6-methoxypyridine has a red shift in its emission spectrum when bound to ruthenium.

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