Organoboranes

Please enquire for more information about 5'-m-Terphenylboronic Acid (contains varying amounts of Anhydride) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4,4,5,5-Tetramethyl-2-(2-(methylsulfonyl)phenyl)-1,3,2-dioxaborolane including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3,4-Bis(2-methylpropyloxy)benzeneboronicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page

B-[4-(2-Bromoacetyl)-3-fluorophenyl]boronic acid is a boron compound that is used in organic synthesis. It reacts with Grignard reagents to produce Grignard reagents. The carbonyl group is susceptible to nucleophilic attack and can be used as a source of bromine. This chemical has been used in the synthesis of ethanediol, which is an important precursor for polymers, plastics, and pharmaceuticals.

Please enquire for more information about 4-Fluoro-2-Methylphenylboronic Acid Pinacol Ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Bromotrimethylsilane is an inhibitor of the enzyme hydroxyl methyl transferases. It binds to the penicillin-binding protein and inhibits the activity of this enzyme, which is involved in the synthesis of bacterial cell walls. Bromotrimethylsilane has been shown to be active against murine sarcoma virus and other viruses as well as bacterial growth. This compound has also been shown to inhibit the growth of several types of cancer cells, including leukemia cells from mice.

Please enquire for more information about 4-Chloro-3-(ethylcarbamoyl)phenylboronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Crisaborole is a topical antimicrobial peptide that was approved by the FDA in 2017 for the treatment of mild to moderate atopic dermatitis and eczema. It belongs to a class of drugs called small-molecule inhibitors of phosphodiesterase 4 (PDE4). PDE4 is an enzyme that hydrolyzes cyclic adenosine monophosphate (cAMP) and thereby reduces the levels of cAMP in cells. Crisaborole binds to the PDE4 enzyme and blocks its activity, leading to an increase in the level of cAMP. This increased concentration of cAMP leads to suppression of inflammation, which is a major symptom associated with skin diseases such as dermatitis and eczema. Crisaborole has shown low toxicity in vivo studies on human volunteers. In a study involving administration of crisaborole at doses up to 300 mg/day for 14 days, adverse events were reported by 3% patients, with no serious adverse