Nitro

Applications 4-Nitrobenzonitrile (cas# 619-72-7) is a useful research chemical.

4-Nitrophenylhydrazine hydrochloride is an organic compound that belongs to the class of hydrazines. It is a colorless solid that has a melting point of 202-204 °C. 4-Nitrophenylhydrazine hydrochloride is used in the synthesis of other compounds, such as trifluoroacetic acid and nucleophilic compounds. The chemical structure can be analyzed using nuclear magnetic resonance (NMR) spectroscopy, which shows that this compound contains amines and nitro groups. 4-Nitrophenylhydrazine hydrochloride is also soluble in water due to its acidic nature. This compound reacts with bases and alcohols to form salts, such as monosodium salt.

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3-Fluoro-4-nitroanisole is a regiospecific synthesised compound that binds to albumin in the human serum. It has been shown to be an endogenous metabolite of 3-fluoro-4-nitrophenol, which is a potent inhibitor of cellular and blood assays for amines. The binding affinity for albumin was about 100 times higher than for other amines such as histamine or tyramine. 3-Fluoro-4-nitroanisole also has a high affinity for anions, with a pKb value of 8.7, which makes it suitable as an anion receptor in applications such as the determination of anion concentration in water samples. This fluoroquinonoid is also used as a fluorescent probe for nucleophilic reactions and can be used to detect nucleophiles in organic solvents by adding it to the reaction mixture.

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6-Methoxy-3-nitroquinoline (6MNQ) is a quinoline that is an enolization catalyst. It reacts with various molecules to form a variety of products, including enediyne compounds, bridgehead compounds, and dynemicin compounds. 6MNQ is not reactive with alkenes or alkynes because its electron density is too low for such reactions. 6MNQ has been used in the synthesis of quinolines and other heterocycles.

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Methyl 3-methyl-2-nitrobenzoate is a chiral, catalytic, and magnetic additive. It is used in the production of alkyl chlorides, cinnolines, and cyclic compounds. Methyl 3-methyl-2-nitrobenzoate can be used as a diagnostic for chloride ions or chlorine gas in water. It also has an important application in wastewater treatment by removing organics from wastewater effluent. Methyl 3-methyl-2-nitrobenzoate can be synthesized from allylic oxidation of methyl benzoate with sodium hypochlorite in the presence of copper sulfate catalyst. The reaction proceeds through an addition-elimination mechanism to produce the desired product and copper(II) chloride as a byproduct. The process occurs on a mesoporous material to increase surface area for the reaction to proceed more quickly and efficiently.

2-Nitro-N1-phenylbenzene-1,4-diamine is a synthetic colorant that is used in the production of dyes, paints, and rubber products. It has been shown to be metabolized by microorganisms and can be detected by spectrometric analysis. 2-Nitro-N1-phenylbenzene-1,4-diamine is also a good indicator for sulfate and basicity.

4-Nitro-1,2,5-oxadiazol-3-amine is a molecule that has been shown to be an inhibitor of the epidermal growth factor receptor (EGFR). The optimal reaction conditions for this molecule were determined by crystallography. These results were confirmed by prognosis assays and the determination of tautomers. This molecule may be used in diagnosis and as a potential treatment for cancer. 4-Nitro-1,2,5-oxadiazol-3-amine binds to the EGFR at a site different from that of erlotinib, an inhibitor currently used in the clinic. This binding leads to inhibition of protein synthesis and cell division by preventing the activation of downstream signal transduction pathways. The molecule also inhibits tumor cell proliferation and induces apoptosis by preventing the production of nitric oxide (NO) and reactive oxygen species (ROS).

3-(5-Fluoro-2,4-dinitroanilino)-2,2,5,5,-tetramethyl-1-pyrrolidinyloxy (FDNP) is a fluorescent molecule that has been used to study the orientation and dynamics of chemical species in muscle fibers. FDNP is a bimodal fluorescent probe that can be excited with laser light at 532 nm or 355 nm. The fluorescence emitted by FDNP varies depending on the orientation of the fluorophore in relation to the excitation light. Using a combination of biochemical, biophysical and computational studies, it was found that FDNP binds to actin and myosin filaments in muscle fibers.

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4-Chloro-3-nitro-5-sulfamoylbenzoic acid is a chemical compound that belongs to the group of speciality chemicals. It is a versatile building block for the synthesis of complex compounds. 4-Chloro-3-nitro-5-sulfamoylbenzoic acid has high quality and can be used as reagents in research or as a building block for the synthesis of new molecules.

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3-Nitropicolinaldehyde is a nitro compound that is prepared by the reaction of aminopyridine, sulfide, and chloride in the presence of hydrosulfite. This reaction is catalyzed by palladium. 3-Nitropicolinaldehyde can be converted to 3-nitrocatechol and then to 2-amino-3-nitrophenol. The cross-coupling method used in this synthetic process provides a high yield and easy demethylation of nitro groups to form vinylic groups. This compound has been shown to undergo a number of reactions with thiosemicarbazide and sodium sulfide.

2,6-Dimethoxy-3-nitrobenzoic acid is an aromatic compound that has been shown to have a molecular weight of 136.2 g/mol. It is extracted from the leaves of "Nepeta cataria" and can be found in many other plants as well. This compound has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis. The mode of action for this compound is not yet known, but it may be due to its ability to form hydrogen bonds with the ribosomes and inhibit nucleotide binding sites on the ribosome surface.

Trans-2,5-dimethoxy-4'-nitrostilbene is a molecule that belongs to the class of polycyclic aromatic compounds. It is used as a versatile building block in organic synthesis, and is also an intermediate for the production of other compounds. Trans-2,5-dimethoxy-4'-nitrostilbene has been shown to be effective in the preparation of various pharmaceuticals such as diazepam and chloramphenicol. It is also used in research chemicals and speciality chemicals. The structure of trans-2,5-dimethoxy-4'-nitrostilbene can be described as a bicyclic compound with two phenyl rings joined by an oxygen bridge. Trans-2,5-dimethoxy-4'-nitrostilbene has CAS No. 552938 4 and molecular weight of 268.81 g/mol.

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N-Nitroso-di-n-butylamine is a nitrosamine that is a product of wastewater treatment. It has been shown to inhibit mitochondrial function and induce liver lesions in rats at high doses. N-Nitroso-di-n-butylamine is structurally similar to the natural substrate ribose, which leads to inhibition of xanthine oxidase, an enzyme involved in purine metabolism. The structural analysis revealed the presence of reactive sites that are susceptible to attack by nucleophiles, such as hydroxyl radicals or hydrogen peroxide. This indicates that N-Nitroso-di-n-butylamine may be a precursor for other carcinogenic compounds. NADH is reduced by NADH dehydrogenase (complex I) in mitochondria to produce NAD+, which subsequently donates electrons to the electron transport chain and generates ATP. The ability of NNDB to inhibit complex I activity was assessed using hl60

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1-Methyl-2-(4-fluorophenyl)-5-nitro-1H-imidazole (1MFNP) is a drug that has been used to treat amoebiasis. It is a quinolone derivative that inhibits the growth of trophozoites by binding to DNA and RNA, thereby inhibiting protein synthesis. 1MFNP also reduces diarrhoea by interfering with the production of fluid in the intestines. The drug has been shown to be effective in clinical studies for the treatment of amoebiasis, although it does not work as well as quinine.

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4-Chloro-3-nitrophenacylbromide is a synthetic compound that has been shown to be effective against cancer cells in vitro. In the presence of light, this substance emits a bright green fluorescence, which is useful for imaging. The synthesis of 4-Chloro-3-nitrophenacylbromide can be achieved by solid phase methods and chemosynthesis. Spirocyclic amines are used as building blocks for the synthesis of this product. This process leads to functionalization strategies with high levels of chirality and drug development.

O-4-Nitrobenzylhydroxylamine hydrochloride (NOH) is a monoclonal antibody that reacts with tissue culture cells and immobilizes them. NOH is used as a diagnostic reagent to detect growth factor β in the human body. This agent has been shown to be effective at inhibiting the growth of certain types of cancer cells in vitro, including those that are resistant to other treatments. NOH also shows potent inhibitory activity towards the dna mutations that lead to the development of cancer. The compound may also have effects on biological function.

4-Nitro-1H-indazole is a chemical compound that has been shown to have anticancer activity. It induces apoptosis in human ovarian carcinoma cells and inhibits the growth of other cancer cells. The apoptotic activity of 4-nitro-1H-indazole is due to its ability to bind to the mineralocorticoid receptor and form a ternary complex with hydrogen bond. This binding prevents the formation of a hydrogen bond between the receptor and DNA, which would normally inhibit apoptosis. 4-Nitro-1H-indazole also has antiinflammatory properties because it blocks prostaglandin synthesis by inhibiting cyclooxygenase 2 (COX2) enzyme activity.

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4-Fluoro-4-nitro-2,5-cyclohexadien-1-one (4FCH) is a dienone that can be prepared by nitration of 4-(nitro)phenol. It is also produced when acetates are heated with nitric acid in the presence of metallic catalysts. The reaction is exothermic and can be carried out at temperatures below 100°C. 4FCH isomerizes to 2,5-dihydrobenzoquinone on heating and reacts with nitrous acid to form 3,4,5,6-tetranitrobenzoquinone (TNBQ).

Bis(fluoroethyl)nitrosourea (BFENU) is a compound that can be used as a diagnostic or therapeutic agent. It is a modification of fluorodeoxyuridine, which is an anticancer drug. BFENU inhibits the production of messenger RNA and DNA in cancer cells. BFENU binds to the guanine base in DNA, which prevents formation of purines and pyrimidines, leading to cell death by lack of nucleic acid precursors for replication. BFENU also has antitumor activity against leukemia cells in vivo. The mechanism of action for this drug is not well understood but may involve base formation with cellular components such as proteins and nucleic acids.

Benzyl4-(benzyloxy)-5-methoxy-2-nitrobenzoate is a potent inhibitor of platelet-derived growth factor (PDGF) receptor phosphorylation. It has been shown to inhibit the proliferation of cultured human platelets stimulated with PDGF and to reduce carotid artery thrombus formation in mice. The compound also inhibits the binding of PDGF to its receptors, which leads to decreased activation of downstream signalling pathways that are involved in cell proliferation and survival. Benzyl4-(benzyloxy)-5-methoxy-2-nitrobenzoate has been shown to have a synergistic effect with methoxyethoxy and ethoxyethoxy, two other inhibitors of PDGF receptor phosphorylation.

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5-Nitrothiophene-2-carboxaldehyde (5NT) is a chemical compound that belongs to the class of dihedral molecules. It is commonly used as an antimicrobial agent and has been shown to have amoebicidal activity in tissue culture. 5NT also inhibits cell growth and proliferation in certain bacteria, such as Staphylococcus aureus strains, by interfering with DNA replication and protein synthesis. Although 5NT is not active against other types of bacteria, it has been shown to be effective against MRSA in laboratory studies. The biological properties of 5NT are still being studied.

2-Nitrophenethylamine is a prodrug that is metabolized to 2-nitrophenol after oral administration. This compound has been studied for its potential therapeutic use in conditions such as cancer, diabetes, and hypertension. 2-Nitrophenethylamine is a benzyl amine with two functional groups, the carboxymethoxy and the azide. The carboxymethoxy group is used for the staudinger reduction of azides to form secondary amines, which are subsequently reduced by hydrogenation to yield 2-nitrophenol. The azide group can be used as an electrophile in the synthesis of heterocycles. The pharmacokinetics of this drug have been studied in rats and dogs; it has shown low bioavailability when administered orally but high bioavailability following intravenous injection.

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4-Chloro-3-nitrocinnamic acid is a useful building block that can be used to synthesize many organic compounds. This compound is a raw material for pharmaceuticals and other organic chemicals. 4-Chloro-3-nitrocinnamic acid is also a versatile building block that can be used as a starting material to synthesize complex compounds such as cis,cis,trans-1,2,5,6,-tetrahydro-4-(methylthio)pyrimidine.

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Difluoro-Dinitromethane (DFDM) is a colorless, crystalline solid that is soluble in aromatic solvents. It has been shown to be an effective solvent for the fluorination of chloro-substituted aromatic compounds. DFDM can also be used as a nucleophile in nitro-substitution reactions. The shift of the frequency of the DFDM molecule from 0.5 to 1.5 GHz is due to a change in the electron distribution between electrons and orbitals. This shift can be used to calculate the parameters for this molecule and its reaction with other molecules or solutes.

5-Nitro-1H-imidazole-2-carboxylic acid (5NIC) is a white to light yellow crystalline powder that is soluble in water and alcohol. It has been used as an intermediate for the synthesis of sulfamethoxazole, metronidazole, and nitroimidazoles. 5NIC is also used as a reagent for the preparation of amides. The compound can be synthesized by reacting diethanolamine with phosphorous oxychloride to form 1,2-dichloropropane, which reacts with nitric acid to produce 5NIC. 5NIC has been shown to be effective against histomoniasis and amoebiasis in chickens. In addition, it can inhibit the growth of Mycobacterium tuberculosis, Mycobacterium avium complex, and Staphylococcus aureus.

4-Nitro benzenebutanoic acid is a synthetic molecule that has not been extensively studied in biological systems. It is a calcium-binding molecule and may be used to study the mechanisms of calcium binding. 4-Nitrobenzenebutanoic acid has also shown some bifunctional activity and is used as a substrate in pharmacokinetic studies. The synthesis of this compound can be achieved by reacting azobenzene with butyric acid in the presence of an amine and inulin. This reaction produces nitrobenzenebutanoic acid, which undergoes hydrolysis to yield 4-nitrobenzenebutanoic acid.

Applications Toxic to some wild and domestic birds and mice. Molluscicidal activity Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References De Abreu, F. et al.; Bioorg. Med. Chem. 9, 659 (2001); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 14, 111 (1985); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 12, 355 (1983)

3-Amino-4-nitropyridine is a nucleophilic amine that can be used to synthesize 3-amino-4-nitropyridines. 3-Amino-4-nitropyridine has been shown to react with chlorides and nitro compounds to form 3,4-dichloropyridines and 3,5-dinitropyridines, respectively. The reaction of 3-amino-4-nitropyridine with methoxyamine forms 4-(3′,5′)-aminopyrimidinium methoxide. This product has been shown to be a stoichiometric reagent in the formation of substituted piperidines from methoxyamine and nitroethane.

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Applications 6-​Amino-​5-​nitrochromen-​2-​one is a reagent used in the synthesis of pyranopyridinediones. References Khan, M. et al.: J. Pure App. Sci., 22, 37 (2004);

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Benzoyl-L-tyrosine p-nitroanilide (BTPNA) is used as a substrate to identify, differentiate and characterize serine carboxypeptidase(s) and various proteases.

7-Hydroxy-3-(4-nitrophenyl)-2H-chromen-2-one is a planar, coplanar, and asymmetric molecule that contains a benzene ring and a coumarin ring. It has been synthesized in the lab by reacting 4-nitrophenol with 3,5-dihydroxyphenylacetic acid in the presence of sodium hydroxide. The molecule was crystallized using x-ray diffraction and found to be dihedral. 7-Hydroxy-3-(4-nitrophenyl)-2H-chromen-2-one shows hydrogen bonding interactions between its phenolic groups and the neighboring -NH group of the coumarin ring.

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Applications A more base-stable alternative to Ellman’s reagent for the quantification of thiol contents and enzymatic assays under basic pH conditions. . It reacts with free thiols similar to Ellman’s reagent but has dramatically improved stability under alkaline conditions, making it an excellent alternative to Ellman’s reagent. References Zhang, H., et al.: Bioorg. Chem., 26, 356 (1998), Chen, Y., et al.: Biochem., 43, 11491 (2004),

2-Nitro-5-(trifluoromethyl)aniline is a synthetic molecule with structural activity. It is a bioisostere of the antimalarial drug albendazole, and has been shown to have antimalarial activity against plasmodium falciparum in vitro. The drug also shows antiprotozoal properties against giardia, vaginalis, and trichomonas. 2-Nitro-5-(trifluoromethyl)aniline is not active on plasmodium species. This drug may be used as an alternative to metronidazole or trichomonas vaginalis for the treatment of trichomoniasis.

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6-Chloro-2-nitrotoluene is a synthetic organic compound that has been identified in environmental samples as a reaction product of chlorine and organic compounds. It has been shown to induce root formation in plants, which is related to its ability to inhibit the formation of chlorinated hydrocarbons. 6-Chloro-2-nitrotoluene can be produced by reacting nitrogen atoms with zirconium at high temperatures and low pressures, requiring an activation energy of 50 kcal/mol.