Amides

Please enquire for more information about Amyloid P Component (33-38) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Met-enkephalin is a potent opioid that binds to mu, delta and kappa receptors in the brain. It is synthesized from Phe-enkephalin by removal of the C-terminal amino acid Phe. Met-enkephalin is a peptide that can be reversibly converted between two forms, A and B, by removing and adding a hydrogen ion. The A form has an active carboxyl group while the B form has an inactive carboxyl group. Met-enkephalin is synthesized by solid phase synthesis on a resin that is regenerated in neutral ph buffer. This drug has been shown to inhibit ATP levels in Caco-2 cells and decrease dopamine release in vitro. It also inhibits receptor binding experiments on rat brains and reversibly inhibits the binding of enkephalins to their receptors at different pH values. Met-enkephalin's conformational properties are determined using molecular modeling software, which predicts its three dimensional

5-(1-Aziridinyl)-2,4-dinitrobenzamide (AZA) is an immunomodulator that activates the immune system. AZA is a hydroxylated form of the parent compound aziridine, and it is known to be an agonist of the transcription-polymerase chain reaction and an inhibitor of the transcription-elongation step. AZA has been shown to have chemopreventive effects in cutaneous lesions and carcinoma cell lines. It also inhibits prostate cancer cells by inducing apoptosis. AZA may be used as a cancer gene therapy agent for squamous carcinoma or as a treatment for other forms of cancer.

Please enquire for more information about 4-(4-Amino-1H-pyrazol-1-yl)butanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Chloro-N-(2,3,5,6-tetrafluorophenyl)propanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Piperazine-1-sulfonic acid, dimethylamide is a potent inhibitor of the enzyme dehydrogenase that has been shown to normalize blood glucose levels in diabetic rats. It is also an inhibitor of sorbitol dehydrogenase and has been shown to alleviate diabetic neuropathy in rats by inhibiting the production of reactive oxygen species. The active site of piperazine-1-sulfonic acid, dimethylamide contains a catalytic cysteine residue that is essential for its activity. This compound belongs to the family of inhibitors which are competitive inhibitors with respect to their substrate, sorbitol.