Aldehydes

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4-Chlorophenyl)acetaldehyde (4CPA) is an aldehyde that has been shown to have inhibitory effects on the oxidation of leukocytes. 4CPA forms a chlorinated acetal with hydrochloric acid, which reacts with styrene and naphthalene to form a decaborane linker. The reaction yield for this reaction is dependent on the concentration of reactants. The mechanism for the formation of 4CPA from chloroform involves a nucleophilic substitution reaction in which the chlorine atom acts as a nucleophile and attacks the electrophilic carbonyl carbon atom in chloroform. Structural studies show that 4CPA can be considered as two molecules of hydrogen chloride bound to an acetal molecule, which may explain its inhibitory activity against peroxide.

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N-Methyl-N-hydroxyethyl-4-aminobenzaldehyde (NHABA) is a bathochromic molecule that absorbs light at wavelengths of 400 to 500 nm. It is reactive and reacts with metal cations to form chromophores. NHABA has been shown to be a fluorescent probe for the detection of tyrosinase and autophagy in human serum. It also has inhibitory properties against tyrosinase, which may be due to its ability to inhibit the formation of melanin. NHABA is used as an analytical chemistry reagent for the determination of ammonia, nitrite, and nitrate ions in water samples. This molecule can also be used as a chemosensor for the detection of phenolic compounds in water samples.

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4-Methoxy-3-(trifluoromethyl)benzaldehyde is a fine chemical that can be used as a building block for pharmaceuticals and other organic compounds. It is also used in research for the synthesis of complex compounds. This chemical has been reported to be a useful intermediate or scaffold for organic syntheses. 4-Methoxy-3-(trifluoromethyl)benzaldehyde is soluble in water and ethanol, and insoluble in ether. It has a melting point of 140°C, boiling point of 249°C, density 1.096 g/cm³, and refractive index (20°C) 1.567.

4-Benzyloxy-2,6-dimethoxybenzaldehyde is a trypsin inhibitor. It has been shown to inhibit the activity of proteases, such as chymotrypsin and trypsin, by forming a covalent bond with the enzyme's active site serine residue. This inhibition blocks the cleavage of peptides at the carboxyl terminus. 4-Benzyloxy-2,6-dimethoxybenzaldehyde has been validated in different biological systems and has been used to study protein modifications and proteomics.

2-Chloro-7-methoxy-quinoline-3-carbaldehyde is a quinoline derivative that has been shown to have antiinflammatory activity in animal models of inflammatory diseases. 2CQA has been shown to bind to the CB2 receptor, which is one of the endocannabinoid receptors. The binding of 2CQA to the CB2 receptor can inhibit inflammation by inhibiting fatty acid production and reducing the production of proinflammatory cytokines that are responsible for inflammation. This drug also has potential as an analgesic agent in cancer pain management, as well as being useful in treating autoimmune diseases such as rheumatoid arthritis and pancreatitis. 2CQA is synthesized by reacting chloroacetyl chloride with 3-hydroxybenzoic acid (3HB). This reaction produces a carbonyl group at the position adjacent to the carbonyl group on the aromatic ring, which is then reduced with magnesium oxide.

3-Bromo-5-fluorobenzaldehyde is an intermediate in the synthesis of a variety of pharmaceuticals. It is used to manufacture drugs that have affinity for muscarinic receptors. In addition, 3-bromo-5-fluorobenzaldehyde can be used to synthesize drugs with affinity for nicotinic acetylcholine receptors, which are found in the autonomic nervous system. 3-Bromo-5-fluorobenzaldehyde is inexpensively made by chlorinating benzaldehyde and then reacting it with hydrogen fluoride. The synthesis has been optimized for high yield and purity by developing a method that produces impurities that are easily removed from the product. This process also provides an easy way to quantitatively measure drug substances and their binding affinities.

1,2-Dihydroacenaphthylene-5-carbaldehyde is a porphyrin that is water soluble and can be used to inhibit singlet oxygen. It has been shown to have an inhibitory concentration of 10 μM in cells. This compound has also been shown to have anticancer activity against breast cancer cells. The quantum yield of this compound is 0.02, which allows it to be used as a photosensitizer for photodynamic therapy (PDT). 1,2-Dihydroacenaphthylene-5-carbaldehyde has also been shown to kill cancer cells by inhibiting the production of reactive oxygen species (ROS) and DNA damage.

Z-Phe-Tyr-aldehyde is a natural compound that inhibits the activity of cathepsin, an enzyme associated with cancer and bowel disease. The compound also inhibits the expression of covid-19, which is a protein that regulates cell death. Z-Phe-Tyr-aldehyde has been shown to cause caspase-independent cell death in human leukemia cells. This compound also blocks the TLR4 receptor, which is thought to play a role in infectious diseases such as SARS and Covid-2. It has been found to inhibit protein synthesis in bacteria, which may be due to its ability to inhibit ribosomal function.

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2-Hydroxy-6-methoxybenzaldehyde is a molecule that can form hydrogen bonds with other molecules. FT-IR spectroscopy has shown that this compound has a copper complex and an acidic proton, which may be due to intramolecular hydrogen bonding interactions. The compound also has been shown to have potent inhibitory activity against cellular growth and cancer cells in vitro. 2-Hydroxy-6-methoxybenzaldehyde is a metal chelator and can therefore bind to metals such as iron and copper. It is genotoxic, which means it damages DNA by causing DNA strand breaks or crosslinks, leading to cell death. This chemical may also cause genetic mutations through the formation of tautomers that make DNA replication difficult. Gel chromatography shows that 2HMB has a low molecular weight (MW) and high solubility.

3,6-Dichloropicolinaldehyde is a chemical compound that is obtained by reduction of 3,6-dichlorobenzonitrile with sodium borohydride in the presence of water. It has been shown to undergo electrochemical reactions at the potentials and parameters investigated in this study. The cyclic voltammetry of 3,6-DCA shows that it has an acidic character due to its electron-donating carboxylate group. Reduction of 3,6-DCA gives rise to a molecule with two half-reactions: one involving the transfer of an electron from a water molecule to the anion and another involving the transfer of hydrogen atoms from the anion to a water molecule.

3,4-Bis(methoxymethoxy)benzaldehyde is an alkaloid that can be found in the leaves of plants such as Piper aduncum and Micranthus coleoides. It has been shown to contain a skeleton consisting of piperidine and methoxy groups. 3,4-Bis(methoxymethoxy)benzaldehyde has been found to have anti-inflammatory properties and may act as a natural flavonoid.

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2,4-Dimethoxybenzaldehyde is a synthetic compound that has been shown to have activity against pancreatic lipase. It has been suggested as a potential drug for the treatment of metabolic disorders such as obesity or diabetes. 2,4-Dimethoxybenzaldehyde can be synthesized by reacting ethyl diazoacetate with an aldehyde in the presence of ammonium acetate. This chemical can also be used to produce ethyl esters and compounds belonging to the group of phlorotannins. 2,4-Dimethoxybenzaldehyde has been shown to have antioxidative activity and inhibitory effects on pancreatic lipase.

4-Fluorobenzaldehyde oxime is a phenylhydrazine derivative that reacts with an aromatic amine to form a ternary complex. The reaction time for this process is short, and the yield of the product is high. 4-Fluorobenzaldehyde oxime also reacts with an aromatic amine to form an ion-pair. It can react with acidic hydrogen donors such as peracids and it also has high hydrogen bonding interactions. 4-Fluorobenzaldehyde oxime is used in pharmacological agents as well as other chemical reactions, including halogenation.

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