Aldehydes

1-Ethyl-3,5-dimethyl-1H-pyrazole-4-carbaldehyde (EDC) is a hydrazine derivative that is used in the manufacture of dyes and pharmaceuticals. It can be prepared by the reaction of benzidine with ethylenediamine or a primary amine. EDC is an important intermediate for the production of many drugs, such as levodopa, methyldopa, and carbidopa. It is also used to make dyes for textiles and paper. EDC has been shown to have carcinogenic effects on animal studies.

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3,5-Dibromobenzaldehyde is an analytical reagent that has been used as a chemosensor. The compound was synthesized by the reaction of benzaldehyde with bromine and potassium hydroxide (KOH). 3,5-Dibromobenzaldehyde has a skeleton consisting of three phenyl groups and two aldehyde groups. The compound also contains two active methylene groups and two vinylene groups. 3,5-Dibromobenzaldehyde can be detected by fluorescence probe or low energy electron diffraction. This chemical is an effective antibacterial agent with an LD50 value of 1.6 milligrams per kilogram in rats.

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3-(4-Fluorophenyl)-1H-pyrazole-4-carboxaldehyde is a cyclic acetal that can be synthesized by condensation of acetone and diazaphenanthrene. It has been extracted from the flowers of Acacia verna.

3-Chloro-2,3-bis(4-methoxyphenyl)acrylaldehyde (3CBA) is a molecule with growth factor β that can be used to stimulate the growth of cells in culture. 3CBA has been shown to induce morphogenetic protein activity and inhibit cancerous cell growth in vitro. It also induces patterning of cells, leading to normalization of differentiation and proliferation. 3CBA has been shown to block the activity of β-catenin and may have the ability to reduce the risk for aneurysms by inhibiting bone morphogenetic protein activity. 3CBA also has potential as a treatment for osteoporosis due to its ability to stimulate bone formation.

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