6-membered Rings

Applications 9-(2-(Benzyloxy)ethyl)-2-((2-(benzyloxy)ethyl)amino)-1H-purin-6-(9H)-one is an intermediate used in the synthesis of 9-(2-Hydroxyethyl)guanine (H942035), which is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor. References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);

Applications Deoxybenzoin Oxime (cas# 26306-06-9) is a compound useful in organic synthesis.

Applications Methyl 4-amino-2,3,5,6-tetrafluorobenzoate (cas# 715-37-7) is a useful research chemical.

Applications 2,4-Dihydroxy-5-((4-sulfophenyl)diazenyl)benzoic Acid is an intermediate in the synthesis of Acid Orange 24 (A189835), which is used in trickling biofilters for wastewater treatment. Acid Orange 24 is used in suncare compositions. It also serves as a raw material for cosmetics. Mutagenicity test for dye compositions in cosmetics. References Garzon-Zuniga, M. A., et al.: Water Environ. Res., 83, 107 (2011); Anon.: IP.com Journal, 11, 5 (2011); Muzzall, J. M., et al.: Mutat. Res., Genet. Toxicol. Testing, 67, 1 (1979)

Applications 5-(3,4-Dichlorophenyl)-2-furoic acid is a reactant in the preparation of dantrolene (D185000) which has a potential to treat vascular dysfunction. References Ellis, K.O., et al.: J. Pharm. Sci., 69, 327 (1980); Harrison, G.G., et al.: Brit. J. Anaesth., 60, 279 (1988); Murasawa, S., et al.: Bioorg. Med. Chem., 20, 6384 (2012);

Applications N-Phenyl 2-Bromo-5-Fluorobenzamide (cas# 949443-48-5) is a useful research chemical.

Applications A redox buffer that increases the folding rate of disulfide-containing proteins realative to traditional buffers such as glutathione and glutathione-disulfide. A useful synthetic intermediate for the preparation of novel antiinflammatory agents. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Gough, J.D., et al.: JACS, 124 (15), 3885 (2002)

Applications Bis(4-allyloxyphenyl)sulfone (cas# 41481-63-4) is a useful research chemical.

Applications N-Benzylethanolamine is used in the synthesis of imidazoles as potent calcitonin (CGRP) antagonists. Also it aids in the preparation of benzofused hydroxamix acids, as useful fragments for the synthesis of histone deacetylase inhibitors. References Tora, G. et al.: Bioorg. Med. Chem. Lett., 23, 5684 (2013); Marastoni, E. et al.: Bioorg. Med. Chem. Lett., 23, 4091 (2013);

Applications A benzoic acid derivative used in the preparation of potent, selective, orally bioavailable matrix metalloproteinase inhibitors. References Wada, C. et al.: J. Med. Chem., 45, 219 (2002)

Applications 1-[2-Hydroxy-4,6-bis(ethoxymethoxy)phenyl]ethanone (cas# 128837-25-2) is a compound useful in organic synthesis.

Applications 1-(3,5-Bis(benzyloxy)phenyl)pentan-2-ol is an intermediate for the synthesis of 2''-Hydroxycannabidiol (H824820), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 2''-Hydroxycannabidiol can be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol. References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)