Glycoscience

2-O-a-D-Glucopyranosyl-L-ascorbic acid is a potent antioxidant compound found in the human body. It is produced by the enzyme tyrosinase from L-ascorbic acid and has been shown to have anti-apoptotic effects on skin cells. 2-O-a-D-Glucopyranosyl-L-ascorbic acid has also been shown to enhance mitochondrial membrane potential and increase the proliferation of skin cells in vitro. The compound has been tested for its ability to prevent radiation damage in mice and was found to be more effective than vitamin C at preventing cell death. 2OAGA can be used as a topical treatment for skin conditions, such as acne or wrinkles, by reducing inflammation and stimulating cellular growth.

Mannitol is a sugar alcohol occurring widely in plants and they are exudates, for example, in olive and plane trees (Collins, 2006). It is produced commercially by the catalytic hydrogenation of fructose (Zelin, 2019). Mannitol is used extensively in food and pharmaceutical industries because of its unique functional properties. It is about 50% as sweet as sucrose and has a desirable cooling effect often used to mask bitter tastes. Mannitol is non-cariogenic and has a low caloric content. Mannitol is an osmotic diuretic that is metabolically inert in humans and is used for: the promotion of diuresis before irreversible renal failure becomes established, the promotion of urinary excretion of toxic substances, as an Antiglaucoma agent, and as a renal function diagnostic aid (O’Neil, 2013). Additonally, in 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients (McKenna, 2020).

Ambrisentan is a synthetic, complex carbohydrate that belongs to the group of glycosylations. It has been shown to have anti-inflammatory and vasodilatory effects in animal studies. Ambrisentan is an inhibitor of angiotensin II type 1 receptor (AT1). It binds to the AT1 receptor and blocks the binding of angiotensin II, resulting in reduced blood pressure. The drug also inhibits the activity of sodium channels in vascular smooth muscle cells, which leads to decreased heart rate. Ambrisentan is used for the treatment of pulmonary hypertension.

(2R, 3R, 4R, 5S) -3, 4, 5- Trihydroxy- N- methyl- 2- piperidinecarboxamide is a synthetic compound that can be used in the synthesis of complex carbohydrates. This compound is fluorinated at the C4 position and glycosylated at the C5 position to make it more stable. It is also methylated at the C6 position and modified by Click chemistry to make it easier to synthesize. The sugar chain has a polysaccharide structure with oligosaccharides linked through alpha 1,6 linkages. This sugar chain is then modified by oxidation of its terminal hydroxyl group to produce a reactive aldehyde that reacts with an amine on an adjacent saccharide unit. This process results in the formation of an alpha 1,2 linkage between two saccharides units.

(R,R)-(+)-1,4-Dimethoxy-2,3-butanediol is a modification of the sugar 1,4-dimethoxy-2,3-butanediol. It is a carbohydrate that can be synthesized and purified to high purity. The synthesis of (R,R)-(+)-1,4-dimethoxy-2,3-butanediol starts with the methylation of glycerol followed by the addition of an alpha hydroxyl group. The final product is produced by glycosylation and polysaccharide synthesis. This modification has been shown to be effective in treating cancer cells and may have potential applications in other areas as well.

2-Isobutyramido guanosine 2',3',5'-tris(isobutanoate) is an oligosaccharide, which is a type of carbohydrate. The structure of this compound is composed of a sugar, the monosaccharide saccharide and the complex carbohydrate. This compound is synthesized by a click modification and fluorination reaction using 2-amino-2-deoxy-D-ribose as the starting material. The product contains glycosylation and methylation modifications.

The objective of this study is to investigate the efficacy of 4-methoxyphenyl 2-azido-4,6-O-benzylidene-2-deoxy-b-D-glucopyranoside (MPAB) as a vaccine adjuvant for the prevention of esophageal candidiasis. MPAB was shown to induce antigen specific immune responses in vitro and in vivo. In addition, MPAB enhanced the protective efficacy of Covid® 19 pandemic influenza vaccine against gastrointestinal infection by Candida albicans. The results from this study provide proof of concept that MPAB can be used as a vaccine adjuvant for the prevention of esophageal candidiasis.

3-O-(β-D-Galactopyranosyl)-D-glucopyranose is a custom synthesis, modification, and fluorination of a monosaccharide. It is a synthetic and modified saccharide. The molecular formula for this compound is C6H10O5 and its molecular weight is 180.17 g/mol. This chemical has been assigned CAS No. 28447-38-3 and has the following structure: The chemical name for 3-O-(β-D-galactopyranosyl)-D-glucopyranose is 3,4,6,2',3'-pentahydroxybenzoic acid β--galactopyranoside with the following structural formula: This compound can be used to produce complex carbohydrate which can be used as an additive in food products or as a pharmaceutical agent. It can also be used in research to study glycosylation reactions,

5-(Acetylamino)-5-deoxy-3-S-phenyl-3-thio-D-erythro-a-L-gluco-2-nonulopyranosonic acid methyl ester 2,4,7,8,9-pentaacetate is a synthetic monosaccharide that can be used for glycosylation and polysaccharide modification. It can also be used as a click chemistry building block to modify sugars. This product has been custom synthesized for the specific needs of our customers. The purity of this compound is greater than 98%.

(5R, 6S, 7R) -6, 7- Dihydro- 5- [(1R) - 1- hydroxyethyl] - 5H- pyrrolotetrazole- 6, 7- diol is a synthetic compound used in the synthesis of various complex carbohydrates. It is a methylated derivative of 2-(2-(4-nitrophenyl) diazenyl)-5H-pyrrolo[2,3-d]pyrimidine and can be synthesized by the click modification of an oligosaccharide or polysaccharide (such as cellulose). This compound has been modified with fluorine and is highly pure. It belongs to the group of monosaccharides and sugars.

Ethyl 3-O-benzyl-4,6-O-benzylidene-D-thiomannopyranoside is a custom synthetic glycosylated compound that is used in the synthesis of oligosaccharides and polysaccharides. This product has a high purity and is modified with fluorine to increase its stability. The CAS number for this product is 173935-67-6.

2,3,4,6-Tetra-O-acetyl-D-galactopyranose is a glycoside that has been used as an antigen in immunological studies and to study the role of fatty acids in cancer. This compound is phosphorylated to form 2,3,4,6-tetra-O-phospho-D-galactopyranose and reacts with primary alcohols to form transglycosylation products. 2,3,4,6-Tetra-O-acetylgalactopyranose also reacts with chloride ions to form disaccharides. As a result of these reactions 2,3,4,6-tetraacetylgalactopyranose has shown anticancer activity.

Gycosaminoglycan in many organs; joint lubricant and shock absorber

Benzyl 4- O- b- D- glucosaminyl-b- D- xylopyranoside is an oligosaccharide that is synthesized by the glycosylation of benzyl 4-O- b -D-glucosaminyl b -D -xylopyranoside with a monosaccharide. The synthesis of this compound is achieved through the modification of the parent compound with a fluorination, methylation, or glycosylation. Benzyl 4- O- b -D- glucosaminyl b -D -xylopyranoside can be found in complex carbohydrates, such as cellulose and starch.

Hydroxy pioglitazone (M-IV) b-D-glucuronide is a synthetic sugar that can be modified to produce a variety of derivatives. It is also known as M-IV, which stands for methylated IV, and has the following chemical structure: O O H H O O H H OH OH HO HO OH OH HO HO OH OH HO HO

Neocarrabiose is a low-energy, hydrogen-bonded sugar that has an optimum concentration of 0.5 M. It is found in the basic structure of oligosaccharides and belongs to group p2. Structural analysis has revealed that Neocarrabiose has a denaturation temperature of 98 °C. Clinical studies have shown that Neocarrabiose may be effective in treating influenza virus, although it is not currently approved for this use. Neocarrabiose can be used as a molecule to form intramolecular hydrogen bonds in organic synthesis and magnetic resonance spectroscopy.

D-Galactosamine (GalN) is an aldohexose (2-Amino-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by an amino group (Collins, 2006). Galactosamine (as the N-Acetyl derivative) forms a key part of both N- and O-linked glycoproteins, glycolipids and glycosaminoglycans. Treatment of experimental animals with D-galactosamine / lipopolysaccharide causes lethal liver injury characterized by apoptosis of the hepatocyte and it is used as a laboratory model to study the effect of therapeutic agents (Hirono, 2001).

Dabigatran 4-Acyl Glucuronide is a synthetic, fluorinated glycosylation of Dabigatran etexilate. It is modified by methylation at the 2 and 3 positions to increase its stability and half-life. This compound also has a high purity with less than 0.5% of impurities and can be custom synthesized to meet specific requirements.

Methyl 2-acetamido-2-deoxy-6-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a carbohydrate that is modified by the addition of a methyl group to the C3 position. The glycosylation of this carbohydrate can be achieved by using a variety of methods, including Click chemistry and Methylation. This product has been custom synthesized for high purity and can be used in various applications, such as Glycosylation and Polysaccharide synthesis.

sugar based 'green' surfactant

2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone is an organic compound that belongs to the class of lactones. It is a chiral molecule with two asymmetric carbons and four stereogenic atoms. This compound can be used for the synthesis of optically active compounds. It is also a precursor for the synthesis of morpholines and phosphonates. 2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone can be synthesized by reacting an enolate with an aldehyde in the presence of a base and acid catalyst. The acid catalyst causes elimination of water from the enolate to produce the desired product.

Lactobionic acid ethyl ester is a custom synthesis of an oligosaccharide that is modified by fluorination, methylation, and click modification. Lactobionic acid ethyl ester is synthesized from the sugar D-glucose and the monosaccharide D-galactose. This product can be used as a substitute for sucrose in food products as it has similar taste, texture and sweetness. It also has many other applications such as being used in the manufacture of polysaccharides and complex carbohydrates.

Produced by the fast pyrolysis of cellulose

5-Deoxy-1,2-O-isopropylidene-5-[(2R-pyridin-2-yl-pyrrolidine)-1-yl]-a-D-xylofuranose is a custom synthesis that has been modified by fluorination, methylation, and monosaccharide addition. This chemical is also known as 5DIPXF.

1,4-Anhydro-6-chloro-6-deoxy-D-glucitol is a complex carbohydrate that has been fluorinated and modified with methyl groups. It can be custom synthesized to produce high purity compounds. 1,4-Anhydro-6-chloro-6-deoxy-D-glucitol is used in synthesis of saccharides and oligosaccharides. The compound has been modified with Click chemistry to produce glycosylation products. It can also be used as an intermediate for the synthesis of sugar derivatives. 1,4-Anhydro-6-chloro-6-deoxy--D--glucitol has the following chemical structure: CAS No.: 301022-81-2 Molecular Formula: C12H24O11 Molecular Weight: 336.35 Melting Point: NA Boiling Point: NA Soluble In

Methyl a-D-xylopyranoside is an iron chelator that can be used as a mycobacterial drug candidate. It binds to both ferric and ferrous iron, and has been shown to inhibit the uptake of ferric iron by Mycobacterium tuberculosis. It also inhibits the synthesis of siderophores, which are molecules produced by bacteria in order to acquire iron from their environment. Methyl a-D-xylopyranoside does not bind to the alpha-d-glucopyranoside moiety typically found in iron complexes. This is due to its hydroxamate group, which causes it to have an increased affinity for Fe3+. This compound is active against gram negative bacteria such as E. coli and Salmonella enterica serovar Typhimurium, but not against gram positive organisms such as Staphylococcus aureus or Streptococcus pneumoniae.

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1-Azido-2,4-O-benzylidene-butane-2,3,4-triol is a synthetic compound that can be used as a methylating agent or to modify saccharides. It is also able to modify polysaccharides and oligosaccharides. 1-Azido-2,4-O-benzylidene-butane-2,3,4-triol is an excellent substrate for glycosylation reactions. This product has been custom synthesized and is of high purity. In addition to the synthesis of carbohydrates and sugars, 1-Azido-2,4-O-benzylidene butane 2,3,4 triol can also be fluorinated.

Methyl 2,3,6-tri-O-benzoyl-4-deoxy-4-chloro-a-D-glucopyranoside is a modification of the sugar monosaccharide. It is an Oligosaccharide with Carbohydrate and Complex carbohydrate. Methyl 2,3,6-tri-O-benzoyl-4-deoxy-4-chloro--a D glucopyranoside is a Custom synthesis that is Synthetic and High purity. It has CAS No. 41881 07 6 and Polysaccharide as its sugar type. This Modification has Fluorination and saccharide as its modification type.

Octahydro-1,2,9-tris-acetoxy-(1S,2R,9S,9aS)-quinolizin-6-one is an oligosaccharide that is a sugar modified with fluorine. It is a synthetic carbohydrate and has the CAS number 57714-00-3. The molecular weight of this compound is 784.61 g/mol. This compound can be custom synthesized to meet your needs and specifications. It has been methylated and glycosylated and has undergone click chemistry modifications.

Please enquire for more information about 2,5-Anhydro-D-mannofuranose oxime including the price, delivery time and more detailed product information at the technical inquiry form on this page

Methyl D-galactofuranoside is a derivative of galactose that is used as an intermediate in the synthesis of other carbohydrates. It can be obtained by trimethylation of methyl galactopyranoside, or by the stepwise reaction of hydrogen fluoride with 1,2-dihydroxyacetone. The product yields are largely dependent on the stereoisomeric form of the starting material. Methyl D-galactofuranoside crystallizes in a monoclinic form and can be synthesized from glucose.

Please enquire for more information about 3,6’-Disinapoyl sucrose including the price, delivery time and more detailed product information at the technical inquiry form on this page

C3-Benzyl-6-O-tert-butyldimethylsilyl-2-deoxy-2-phthalimido-b-D-glucopyranoside is a synthetic glycosylation agent that converts carbohydrates to sugar derivatives. It is a fluorinated sugar with a benzyl group and can be used in the synthesis of complex polysaccharides and saccharides. C3BzTBDMSG has been shown to have high purity, which makes it an ideal choice for Click chemistry and modification.

a-D-Galactosyl-mannotriose is an mannose heavy oligomer

1,2,3,4-Tetra-O-pivaloyl-6-O-trityl-b-D-glucopyranose is a trityl derivative of glucose that can be used as a diagnostic agent for the assessment of cancer. When labeled with radioactive iodine, 1,2,3,4-Tetra-O-pivaloyl-6-O-trityl-b-D-glucopyranose has been shown to accumulate in bile and esophageal cancer cells. Magnetic resonance imaging (MRI) was used to evaluate the distribution of 1,2,3,4 tetra O pivaloyl 6 O trityl b D glucopyranose in patients with cirrhosis. The results suggest that this compound can be used as an indicator for the diagnosis of liver disease.

4-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-L-fucopyranose is a synthetic oligosaccharide that is synthesized from the sugar 4-O-(2,3,4,6 tetraacetyl) fucose. It can be used as a substrate for glycosylation reactions and may also be used to modify other compounds. This product can be fluorinated or methylated and has a CAS number. The purity of this product is high with no detectable impurities.

6-O-Benzyl-1-(-)-carboxymenthyl-2,3:4,5-di-O-cyclohexylidene-L-myo-inositol is a synthetic oligosaccharide with the chemical formula C9H14FNO5. It is a monosaccharide composed of a single sugar unit, inositol, which has been modified with benzyl groups on the 6th and 1st positions of the inositol ring. This compound is used as an intermediate in the synthesis of other saccharides.

D-[UL-13C6,15N]Glucosamine HCl is a complex carbohydrate that can be custom synthesized to order. It is a synthetic sugar that has been modified by Click chemistry. The synthesis of this product requires the use of fluorination and glycosylation reactions. This product can be used in a variety of applications including methylation, modification, or oligosaccharide synthesis. D-[UL-13C6,15N]Glucosamine HCl is also known as glucosamine hydrochloride and has CAS number 1088-96-4.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Man-1 N-glycan is a synthetic oligosaccharide with a sugar chain that is terminated by an alpha-D-mannose. It is synthesized using the Click reaction and modified with fluorine. This product can be used in glycosylation, or the addition of sugar chains to proteins or lipids. Man-1 N-Glycan has high purity and can be custom synthesized to order.

High mannose oligosaccharide found in urine of mannosidosis patients

Please enquire for more information about Methyl 3-O-(2-acetamido-2-deoxy-b-D-galactopyranosyl)-a-D-galactopyranoside including the price, delivery time and more detailed product information at the technical inquiry form on this page

Lambda-Carrageenan is a non-gelling sulphated galactan extracted from red seaweed (typically Gigartina stellata and Chondrus crispus). The structure of all carrageenans consists of a strictly alternating masked repeating unit of 1,3-linked α-D-galactose and 1,4-linked β-D-galactose. λ-Carrageenan has the α-linked unit 2-6-disulphated and the β-linked unit is 2-sulphated. The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.

Resource for the synthesis of Clofarabine and other bioactive arabinosides

Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cut-off molecular weights are produced commercially for this and other applications. A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.

Used to treat duodenal ulcers, GERD, stress ulcers; acid buffer; cytoprotective

Ondansetron 6-D-glucuronide is a modified form of the active drug, ondansetron. It is a mixture of two isomers: (2S,3R)-2-(4-methoxybenzoyl) 3-hydroxy-1,6-diphenylhexane and (2S,3S)-2-(4-methoxybenzoyl) 3-hydroxy-1,6-diphenylhexane. Ondansetron 6-D-glucuronide is used as an antiemetic in the prevention of nausea and vomiting caused by cancer chemotherapy and radiation therapy. This compound is custom synthesized for high purity and efficacy in preventing nausea and vomiting. Ondansetron 6D glucuronide binds to the serotonin 5HT3 receptor on the nerve cells in the gastrointestinal tract and brain that control vomiting.

Please enquire for more information about 4-Amino-4-deoxy-D-glucopyranose including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-Deoxy-1-nitro-L-galactitol is a compound that has been shown to inhibit serine protease and glutaminyl cyclase activity. It is commonly used in laboratory settings as a potassium substitute in media formulations. This compound belongs to the class of monosaccharides known as glutaminyl derivatives. It has been studied for its potential as an inhibitor of nafamostat, a serine protease inhibitor used in the treatment of pancreatitis and disseminated intravascular coagulation (DIC). Additionally, 1-Deoxy-1-nitro-L-galactitol has been investigated for its potential as a disinfectant and as an adrenergic receptor agonist. Preliminary studies have also suggested antiviral properties against certain viruses. Further research is needed to fully understand the potential applications of this compound.

2,3,4-Tri-O-acetyl-alpha-L-fucopyranosyl bromide is a methylated alpha-L-fucopyranosyl bromide that is used as a glycosylation reagent for the synthesis of complex carbohydrates. It is also used in Click chemistry and has been shown to be an effective and selective glycosylation agent. 2,3,4-Tri-O-acetyl-alpha-L-fucopyranosyl bromide is available at high purity and can be custom synthesized to your specifications. This compound has CAS number 16741-27-8 and is listed on the FDA Inactive Ingredient Database (IID).

(1R) -1- [(2S, 3R) - 3- Hydroxy- 1- ((4-methoxyphenyl)methyl) - 2- azetidinyl] -1, 2- ethanediol is a sugar compound that can be methylated and modified to make other compounds. The compound's CAS number is 440636-00-0. This product is a carbohydrate that can be used as a modification for saccharides and polysaccharides. It can also be used as a glycosylation agent or an Oligosaccharide. This product is available in high purity and custom synthesis with the desired modifications.

Hybrid Glycan, 2-AB labelled is a custom synthesis of a high purity glycosylation product. This synthetic oligosaccharide includes saccharides that are labelled with 2-AB. The modification is Click chemistry and provides a method for attaching the label to the sugar molecule. This product is not found in nature or existing in cells or organisms. It is used as a research tool in immunology, cell biology, and structural biology applications.

N6-Benzyladenine-3-glucoside is a carbohydrate that is modified with a click chemistry reaction. It is synthesized from D-mannose and 6-benzylaminopurine and has been glycosylated with 2,3,4,6-tetra-O-acetyl glucosamine. N6-Benzyladenine-3-glucoside is an important component of the bacterial cell wall. The compound consists of a single sugar chain and is fluorinated at the C2 position.

Cyanomethyl 2,3,4,6-tetra-O-acetyl-b-D-thiogalactopyranoside is an important reagent for the synthesis of glycosides and oligosaccharides. This substance has been used to synthesize a variety of modified saccharides, such as methylated sugars and fluorinated saccharides. It also has been applied to the synthesis of complex carbohydrates with the click modification.

L-Glycero-D-manno heptose peracetate is a custom make to order saccharide.

1-OAcetyl-2-O-benzoyl-3-O-tert-butyldiphenylsilyl-L-threofuranose is a modification of the carbohydrate. It is an oligosaccharide that has been synthesized by custom synthesis. It is an artificial monosaccharide type with a methyl group at C1 and a tertiary butyldiphenylsilyl group at C2. The CAS number for this compound is 1971879-01-2, and it has been fluorinated. This compound belongs to the saccharide class, which includes sugars and polysaccharides.

8-Methoxycarbonyloctanoyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside is a carbohydrate which is synthesized by the reaction of 8-methoxycarbonyloctanoic acid and D-galactose. It is an oligosaccharide that has been modified with fluorine on the C2 position of the sugar ring. This product can be used as an analytical reagent for saccharides and carbohydrates.

Used for structural and conformational studies and as enzyme substrates

Please enquire for more information about Fructosazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

This compound is a custom synthesis for Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide and saccharide. It has CAS No. and Polysaccharide as Carbohydrate. The molecular weight of this compound is

Phenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a custom synthesis of the sugar phenyl 2-acetamido-3,4,6-tri-O-acetyl--2 deoxy--b D glucopyranoside. It is a modification of the monosaccharide and glycosylation. This synthetic compound has a CAS number of 1308921 9 and is used as an intermediate in the production of saccharides. Phenyl 2 acetamido 3,4,6 tri O acetyl 2 deoxy b D glucopyranoside is also classified as an oligosaccharide or complex carbohydrate.