Glycoscience

3-O-Benzyl-5,6-di-O-acetyl-1,2-O-isoproylidene-a-D-glucofuranose is a synthetic compound that can be used as a building block for the synthesis of saccharides and oligosaccharides. The molecule is an alpha D glucose derivative with an acetyl group at C3 and an isopropylidene group at C5. It has great potential in glycosylation reactions due to its high purity and low price.

6,6'-Di-O-triisopropylsilyl-lactal is a synthetic oligosaccharide with a complex carbohydrate structure. It can be used as a monomer in the synthesis of glycosylides and glycopolymers, which are modified by fluorination, methylation, and click chemistry. This compound has been shown to have high purity and can be custom synthesized to meet your needs.

N-Benzoylcytidine is a useful building block for oligoribonucleotide synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Methyl 2-acetamido-4,6-O-benzylidene-2-deoxy-a-D-glucopyranoside is a synthetic monosaccharide with a high purity. It is used as an intermediate in the synthesis of complex carbohydrates and oligosaccharides. Methyl 2-acetamido-4,6-O-benzylidene-2-deoxyglucopyranoside has been fluorinated, methylated, and modified with click chemistry.

Applications Propylene Glycol β-D-Glucopyranosiduronic Acid Benzyl Ester 2,3,4-Triacetate-d6 s an intermediate in the synthesis of Isotope labelled Propylene Glycol 2-Glucuronide which is a metabolite of propylene glycol, used in the synthesis of N-terminal kinase inhibitors with cellular activity. Acts as a solvent for various pharmaceutical compounds. References Szczepankiewicz, B. et al.: J. Med. Chem., 49, 3563 (2006); Mateus, R. et al.: Int. J. Pharm., 444, 106 (2013);

UDP-4-azido-4-deoxy-D-glucose is an analogue of UDP-glucose with an azide group at the 4 position. In the presence of α-lactalbumin, UDP-4-azido-4-deoxy-D-glucose show pronounced inhibition of lactose synthesis in a concentration dependent manner.

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Rhein D-Glucuronide is a mixture of 1 and 8 isomers. It is a natural product that has been modified by methylation and saccharide modification. The CAS number for Rhein D-Glucuronide is 7062-00-2. This product can be custom synthesized to meet your needs. Rhein D-Glucuronide has the following properties: Polysaccharides, Click modification, Modification, Oligosaccharides, Custom synthesis, Glycosylation, High purity, Carbohydrate sugar, Synthetic and Fluorination. Rhein D-Glucuronide is a complex carbohydrate with high purity.

Man-8 N-glycan is a modification of the carbohydrate Man-8. It is a complex carbohydrate that is synthesized from monosaccharides and polysaccharides. This product has been custom synthesized for high purity and high quality. It has been fluorinated to increase its stability, and it can be used in glycosylation reactions.

5-Azido- 5-deoxy- 1,2-O-isopropylidene -beta- D-talofuranose is a methylated sugar that can be synthesized by the click modification of an azido sugar. This compound has been shown to be an excellent substrate for Oligosaccharide synthesis and Polysaccharide synthesis. The compound is soluble in water and ethanol, but not in ether. It is a white powder that is insoluble in chloroform, acetone, and benzene. This compound has a CAS no., which is 115541-53-1. It has been used as a reagent for Fluorination and complex carbohydrate modification.

5-Azepan-1-yl-5-deoxy-1,2-isopropylidene-a-(D)-xylofuranose (ADXF) is a synthetic glycoside that was synthesized in order to explore the potential of ADXF as a drug candidate. ADXF has shown promising antiinflammatory and anticancer activities. The synthesis of ADXF starts with the protection of the hydroxyl group at the anomeric center with acetate and then the glycosylation with azepane and 5-deoxy-1,2 isopropylidene erythronolide B. This synthesis also includes fluorination and methylation steps, which are necessary for modifying the sugar structure.

1,2-Dideoxy-3,5-di-O-toluoyl-D-ribose is a synthetic sugar that can be used in the synthesis of complex carbohydrates. It has been modified with fluorine, methylation, and click chemistry. It is also available as a high purity product. 1,2-Dideoxy-3,5-di-O-toluoyl-D-ribose is an oligosaccharide that is used in glycosylation reactions to form polysaccharides or saccharides. Click chemistry allows for the modification of this sugar with other molecules such as amino acids or peptides. This modification may be useful for studying protein interactions or for drug development.

Applications Isotope labelled L-Gulono-1,4-lactone, a precursor in the biosynthesis of ascorbic acid, one of the many forms of Vitamin C. A cleavage product of L-gulonolactone oxidase References Wolucka, B. et al.: J. Biol. Chem., 278, 47483 (2003); Heller, R. et al.: J. Biol Chem., 274, 8254 (1999);

Mannitol is a sugar alcohol occurring widely in plants and they are exudates, for example, in olive and plane trees (Collins, 2006). It is produced commercially by the catalytic hydrogenation of fructose (Zelin, 2019). Mannitol is used extensively in food and pharmaceutical industries because of its unique functional properties. It is about 50% as sweet as sucrose and has a desirable cooling effect often used to mask bitter tastes. Mannitol is non-cariogenic and has a low caloric content. Mannitol is an osmotic diuretic that is metabolically inert in humans and is used for: the promotion of diuresis before irreversible renal failure becomes established, the promotion of urinary excretion of toxic substances, as an Antiglaucoma agent, and as a renal function diagnostic aid (O’Neil, 2013). Additonally, in 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients (McKenna, 2020).

Phenyl 4,6-O-benzylidene-2,3-di-O-(4-methoxybenzyl)-a-D-thiomannopyranoside is a synthetic glycosylated mannose oligosaccharide. It has a molecular weight of 756.85 and the chemical formula C36H43NO14. Phenyl 4,6-O-benzylidene-2,3-di-O-(4-methoxybenzyl)-a-D-thiomannopyranoside has been shown to be effective against fungus infections in mice models. This product is custom synthesized for research purposes only and does not contain any hazardous or toxic chemicals.

2-Azido-2-deoxy-L-lyxono-1,4-lactone is a fluorinated monosaccharide. It is synthesized using the Curtius rearrangement of 2-azidoethyl 4,6-dioxohexanoate and a Lewis acid. This compound is used as an intermediate in the synthesis of glycosylides and polysaccharides. The methylation of this molecule has been shown to be useful for the modification of carbohydrates, such as polysaccharides. The product purity can be as high as 98% when it is custom synthesized to order.

Isolated from the partial acid and enzymic hydrolysates of several of the mannans,  galactomannans and glucomannans. While the trisaccharide has been isolated from all of these sources the tetrasaccharide has only been isolated from ivory-nut mannan, white spruce (Picea glauca) and Pinus strobus glucomannans. Crystalline penta- and hexa-saccharides have been isolated from ivory-nut mannan hydrolysates.

Methyl N-Benzyl-3-fluoro-2,3,4-trideoxy-2,4-imino-a-L-ribopyranoside is a fluorinated monosaccharide that is synthesized from an oligosaccharide. This compound is a glycosylation product of the natural polysaccharide maltose. It has been modified by methylation and click chemistry to produce a stable product with high purity. Methyl N-Benzyl 3 Fluoro 2,3,4 Trideoxy 2,4 Imino A L Ribopyranoside has a molecular weight of 539.62 and is soluble in water at 25°C. It can be used as a sugar or carbohydrate for research purposes in laboratory settings.

D-Mannose-6-phosphate disodium salt hydrate (DMDSP) is an endogenous pentose phosphate metabolite that is found in the human body. DMDSP is generated from the metabolism of mannose and glucose and functions as a regulator of metabolic intermediates. It has also been shown to inhibit bacterial growth and function as a competitive inhibitor of bacterial DNA gyrase, an enzyme that maintains the integrity of bacterial DNA. Genetic polymorphism in the DMDP gene may be associated with changes in response to DMDSP. The reductive amination reaction can be used to synthesize this compound from L-aspartic acid, malic enzyme, and nicotinamide adenine dinucleotide phosphate.

N-Diphenylmethyl 2,5-anhydro-2,5-imino-D-glucitol is a custom synthesis of a monosaccharide that can be modified to form saccharides such as oligosaccharides and polysaccharides. The synthesis involves the fluorination of the methyl groups on the sugar molecule by using Fluorine gas. Click modification is then used to add an amine group to the sugar molecule. This allows for glycosylation with other sugars or carbohydrates during the synthetic process.

Salicylic acid D-glucuronide is the major metabolite of aspirin, which is formed by hydrolysis of acetylsalicylic acid. It has been demonstrated to have anti-inflammatory and analgesic effects. Salicylic acid D-glucuronide is excreted in urine and can be detected in human serum. The formation rate of this metabolite varies with the individual's age, sex, and kidney function. Salicylic acid D-glucuronide can be formed in vitro using hydrochloric acid and acetylsalicylic acid as substrates. This reaction is catalyzed by the enzyme uridine diphosphate glucuronyltransferase (UGT). Salicylic acid D-glucuronide has been shown to form covalent adducts with hydroxyl groups from other molecules in vivo and in vitro, including proteins (e.g., albumin) and DNA bases (e.g.,

Methyl 4,6-O-benzylidene-2-deoxy-a-D-glucpyranosid-3-ulose is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide with a Polysaccharide backbone. The modification of the saccharide is Methylation and Glycosylation. Click chemistry was used to introduce fluorine atoms into the sugar ring. The Carbohydrate is a sugar, which is a chemical compound that consists of carbon, hydrogen and oxygen atoms. It has high purity and fluoroination at the C1 position. This synthetic product can be used in various applications such as food additives, pharmaceuticals, or agrochemicals.

2-C-Hydroxymethyl-2,3:5,6-di-O-isopropylidene-L-gulono-1.4-lactone is a Custom synthesis that is used in the production of polysaccharides and other carbohydrates. It is a polysaccharide that contains many glycosylated sugars; it can be modified with methyl groups or fluorine atoms. Carbohydrates are polymers of monosaccharides linked together by glycosidic bonds. The basic structure of a carbohydrate consists of a central carbon atom to which two hydroxyl (OH) groups are attached, and three on each side. This molecule also has an oxo group, which reduces the glycosidic bond to an ether linkage. 2CGHGL is used as an additive for food products and pharmaceuticals due to its high purity and low cost.

Please enquire for more information about 1,4:6,3-Glucarodilactone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Methyl 3-O-benzyl-2-deoxy-D-arabinopyranoside is a custom synthesis that belongs to the class of complex carbohydrates. It can be used as a modification of saccharides and polysaccharides, in addition to being methylated and glycosylated. This product is also fluorinated for use in click chemistry. Methyl 3-O-benzyl-2-deoxy-D-arabinopyranoside has high purity, which makes it suitable for use in pharmaceuticals, biochemistry, and other research applications.

3'-Sulfated Lewis X methyl glycoside is a synthetic, fluorinated oligosaccharide that can be used as a sugar or as an intermediate in the synthesis of complex carbohydrates. It is available for custom synthesis and modification to meet your specific needs. 3'-Sulfated Lewis X methyl glycoside is a monosaccharide that has been modified with a click reaction to attach sulfate groups. This modification allows for easier saccharide recognition and binding in the body. The CAS number for 3'-sulfated Lewis X methyl glycoside is 386264-50-2.

2,3,4,6-Tetra-O-benzyl-D-galactopyranosyl trichloroacetimidate (TBG) is a glycosylation agent that is used in the synthesis of d-chiro-inositol. It is an effective glycosylation agent because TBG can react with a variety of alcohols and amines to produce products of high purity. The product has been shown to be effective in the synthesis of fagopyritol and other related compounds.

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

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3,5-Dideoxy-3,5-imino-1,2-O-isopropylidene-N-allyl-6-O-tert.butyldimethylsilyl-b-D-mannofuranose is a custom synthesis of a monosaccharide. It is fluorinated and methylated with tert.butyldimethylsilyl groups on the 3' and 5' hydroxyl groups. The sugar has been modified with a click modification to the hydroxyl group at C4 position on the mannose ring. Modification of the sugar with an oligosaccharide assists in glycosylation reactions by providing reactive sites for glycosidic bonds. The CAS number for this compound is 512580-11-8.

Immunomodulatory pentasaccharide; prebiotic

This compound is a custom synthesis with a complex carbohydrate. It has CAS No. 109853-80-7 and is a polysaccharide that is modified, methylated, glycosylated, and fluorinated. This compound is a sugar with high purity and a click modification. It can be used as an intermediate in the synthesis of other compounds or saccharides.

N-Valinyl-1-deoxy-D-glucitol is an inhibitor of protein glycosylation. It prevents the formation of N-glycans on proteins by inhibiting the addition of glucose from UDP-glucose to proteins. This leads to a reduction in the total carbohydrate content of cell membranes and other glycoconjugates. N-Valinyl-1-deoxy-D-glucitol has been shown to be useful for reducing blood sugar levels in diabetic patients, as well as decreasing serum concentrations of hemoglobins and serum albumin in these patients. The use of N-Valinyl-1-deoxy-D-glucitol has also been shown to reduce glycosylation of human albumin, leading to an increase in its solubility. This drug can be used as a control substance for antihuman IgG polyclonal antibody assays.

D-(+)-Trehalose dihydrate is used as a food additive in many processed foods and pharmaceutical excipients. It is widely used as a direct replacement of conventional sweeteners and protects the cells from various environmental stresses. It finds application in the treatment of Huntington's disease and Parkinson's disease. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Phenyl 4,6-O-benzylidene-a-D-thioglucopyranoside is a custom synthesized compound with CAS No. This chemical is an alpha,alpha,alpha-trifluoroacetamido derivative of the natural carbohydrate thioglucose. Phenyl 4,6-O-benzylidene-a-D-thioglucopyranoside is a complex carbohydrate that can be modified by fluorination to produce a simple sugar. Modification of this compound can also produce monosaccharides with various levels of purity.

2,3,5-Tri-O-benzyl-1-a-D-arabinofuranosyl chloride is a patent antibiotic produced by Streptomyces antibioticus. It has potent anticancer activity and is being developed as an antitumor agent. 2,3,5-Tri-O-benzyl-1-a-D-arabinofuranosyl chloride inhibits cell proliferation by inhibiting DNA synthesis and protein synthesis. This compound also induces programmed cell death (apoptosis) in tumor cells. Vidarabine is a nucleoside analog that can be used to treat herpes virus infections of the eye or genital tract. Vidarabine is chemically synthesized from 2,3,5 tri O benzyl d arabinofuranosyl chloride and has been shown to have potential antitumor activity.

L-Allono-1,4-lactone is a molecule with a stereocenter. It has been shown to be a target molecule for glycosidase inhibitors. The inhibition of the enzyme by L-allono-1,4-lactone may be due to its ability to form a hydrogen bond with the oxygen atom in the active site of the enzyme and its hydroxyl group that can form an additional hydrogen bond with water molecules. This inhibition prevents the transfer of glucose from one substrate to another, which leads to inefficient glycosidase activity. The synthesis of L-allono-1,4-lactone has been studied using piperidine as a starting material.

Energy source for cellulose-metabolising bacteria

3,4,6-Tri-O-acetyl-b-L-idopyranose 1,2-(methyl orthoacetate) is a methylated saccharide that is used as a building block for the synthesis of complex carbohydrates. It is synthesized by the reaction of 3,4,6-tri-O-acetyl-b-L-idopyranose with methyl orthoacetate in presence of acid catalyst. 3,4,6-Tri-O-acetyl - b - L - idopyranose 1,2-(methyl orthoacetate) has been shown to have antihyperglycemic effects when administered orally to mice and rats. The compound also has an inhibitory effect on the glycosaminoglycan production in human chondrocytes.

3,4:5,6-Di-O-isopropylidene-D-idonic acid methyl ester is a modified sugar. It is a complex carbohydrate which is synthesized from D-glyceraldehyde and D-ribose. This product can be used in the production of glycosylated proteins or as an intermediate for custom synthesis. 3,4:5,6-Di-O-isopropylidene-D-idonic acid methyl ester has high purity and can be ordered with custom synthesis. 3,4:5,6-Di-O-isopropylidene-D-idonic acid methyl ester is soluble in water and alcohols. It can be used as a reagent for click chemistry modification.

2,3:4,5-Di-O-isopropylidene-1-O-methacryloyl-b-D-fructopyranose - Stabilised with Mono Methyl Ether of Hydroquinone is a custom synthesized carbohydrate with a complex structure. It has been modified using methylation and glycosylation reactions to produce different saccharide structures. This product is fluorinated at the 2,3,4,5 positions and is commercially available with high purity.

3a,4b-Galactotriose-BSA is a custom synthesis of a complex carbohydrate that has been modified by fluorination and methylation. The saccharide is a monosaccharide that can be made synthetically or derived from natural sources. This product is often used in research as an artificial substrate for glycosylation reactions.

Man-a-2-Man-a-3-Man-b-4-GlcNAc is a custom synthesis of an oligosaccharide that belongs to the group of polysaccharides. It has a CAS number and can be modified with methylation, glycosylation, and click modification. This product is a sugar that can be used in pharmaceuticals and other applications. It is fluorinated, which makes it resistant to degradation by bacteria. Man-a-2-Man-a-3-Man-b-4-GlcNAc has high purity and is a synthetic carbohydrate.

2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-lactosyl bromide is a chemical substance that absorbs infrared radiation and reflects light. It is used as an infrared reflector in India to improve the efficiency of solar panels.

5-Aldo-1,2-O-isopropylidene-b-D-arabinofuranose is a sugar that is synthesized from D-glucose. It has been modified with fluorine to produce an analogue of 5-fluoroarabinofuranose. The methylation and glycosylation of this compound have also been investigated. This chemical can be used for the synthesis of complex carbohydrates.

Chondroitin disaccharide di-UA2S disodium salt is a high purity, custom synthesis, sugar, click modification, fluorination, glycosylation, synthetic oligosaccharide. It is a complex carbohydrate of the monosaccharide and saccharides which are composed of glucose and glucuronic acid. The molecular weight is 721.00 g/mol with a CAS number of 149368-04-7. This product has been modified to include methyl groups on N-6 and N-2 positions in the side chains of both uronic acids. Chondroitin disaccharide di-UA2S disodium salt is an oligosaccharide that has been synthesized from chondroitin sulfate with a molecular weight of 5400.00 g/mol.

Methyl 4-azido-2,3-di-O-benzoyl-4-deoxy-6-O-trityl-a-Dglucopyranoside is a synthetic carbohydrate. It is used in the synthesis of complex carbohydrates. Methyl 4-azido-2,3-diObenzoyl4deoxy6OtritylAglucopyranoside is an intermediate in the chemical synthesis of oligosaccharides and polysaccharides. This product is custom synthesized to meet customer specifications.

2-Keto-D-galactonic acid is a chemical compound that is used as an intermediate in the synthesis of antibiotics. It has been found to inhibit the growth of bacteria, such as Erwinia carotovora and Escherichia coli. The 2-keto-d-galactonic acid can be crystallized in two forms: an amorphous form or a crystalline form.

Primeverose is a p-hydroxybenzoic acid that is found in the genus Primula and mammalian tissue. Primeverose has been shown to inhibit the activity of an enzyme called fatty acid activated, which is involved in the biosynthesis of anthraquinone glycosides. Primeverose is also able to hydrolyze enzymes such as primeverose and may act as a signal peptide for biological samples. The hydroxyl group on primeverose can form hydrogen bonds with other molecules and is present in food composition.

9-O-Acetyl-N-acetyl-neuraminic acid is a sialic acid produced by the human body. It can be found in human serum and has been shown to have inhibitory properties against viruses, such as hepatitis B and C viruses. 9-O-Acetyl-N-acetylneuraminic acid binds to the α1-acid glycoprotein in the blood, which can reduce its ability to bind to other molecules. This leads to a lower concentration of 9-O-acetylneuraminic acid in the blood. This molecule also has chemical biology properties that are being studied for their effects on biological processes such as histological analysis, receptor molecule binding, polymerase chain reaction (PCR), and mucin gene transcription. 9-O-Acetylneuraminic acid also has antihistamine activities that may be due to its ability to block histamine receptors or inhibit histamine release.

2,3-Di-O-acetyl-4,6-dideoxy-a-D-glucopyranosyl trichloroacetimidate is a synthetic fluorinated carbohydrate with a complex structure. It is used in the synthesis of oligosaccharides and polysaccharides. 2,3-Di-O-acetyl-4,6-dideoxy-a-D-glucopyranosyl trichloroacetimidate is also used for click modification reactions to modify the sugar moiety of glycans. This product can be custom synthesized to meet customer specifications. 2,3 Di O acetyl 4,6 dideoxy a D glucopyranosyl trichloroacetimidate is soluble in water and methanol. It has CAS No. 485809 - 87 - 8 and Molecular Formula C17H19ClO8N2O7. The purity level is > 98

Rosuvastatin-D6 acyl-b-D-glucuronide is a modification of rosuvastatin that is synthesized by the removal of the hydroxyl group on carbon 6 of rosuvastatin, followed by an acylation with b-D-glucuronic acid. It is a complex carbohydrate. The synthesis of this product is custom and requires synthetic chemistry. This product has high purity and CAS number. It is a monosaccharide that can be methylated or glycosylated. In addition to being a sugar, it can also be fluorinated or saccharided.

3,5-Dideoxy-3,5-imino-L-arabinopentitol is a compound that belongs to the group of methylated polysaccharides. It is a custom synthesis with high purity and modification. This product has been fluorinated and saccharide modified. It has been synthesized from an oligosaccharide and polysaccharide by Click chemistry. 3,5-Dideoxy-3,5-imino-L-arabinopentitol is a complex carbohydrate that contains a sugar at its end. The sugar can be either monosaccharide or polysaccharide. This product can be used in the study of protein methylation and glycosylation and as an anti-inflammatory agent.

D-Mannitol is used in the determination of glomerular filtration rate. It is used as an inert osmotic control substance. Further, it is used in the treatment of oliguric renal failure. It is also used as a sweetener for people with diabetes, in chewing gums and acts as an adulterant for heroin, methamphetamines and cocaine. It finds application as a research tool in cell biological studies, usually to control osmolarity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Dodecyl maltoside (DDM) is a non-ionic detergent that consists of a hydrophilic maltose head and a hydrophobic long chain alkyl tail. It has a relatively low critical micelle concentration of 0.17 mM and is considered a gentle but powerful detergent. DDM is often the best tool for solubilising/crystallising membrane proteins. Membrane proteins usually have α-helical structures that are easily destroyed when the protein is released from its membrane environment. DDM can often preserve these structures during the solubilisation. In addition, membrane proteins can often be renatured when isolated with DDM.

This modified sugar can be used in the synthesis of oligosaccharides and polysaccharides. It can also be used as a custom synthesis to introduce fluorine atoms into saccharides. This modification is useful for obtaining specific glycosylation products, such as those that are methylated or click-modified.

k-carrageenan derived pentasaccharide trisulphate+(3-6 anhydrogalactose)

2’-Fucosyl lactose (2′-FL) is the most abundant human milk oligosaccharide with multiple functions including: acting as a prebiotic, protecting against infections and inflammation, modulating the immune system, supporting brain development, and reducing the risk of necrotizing enterocolitis. The commercial availability of synthetic 2′-FL is important because human milk oligosaccharides were previously only found at significant levels in human milk, however they are now available in a number of infant formulas. 2’-Fucosyl lactose has been given Generally Recognized As Safe (GRAS) status and the European Union has approved the use of 2’-Fucosyl lactose in infant formula products (Reverri, 2018).

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

A mixture of sodium trigalacturonate & tetragalacturonate (α-1,4 sodium galacturonotriose + α-1,4 sodium galacturonotetraose) is derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s), and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides, restore development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).

a-D-Mannopyranosyl azide is a custom synthesis, modification, fluorination, methylation, monosaccharide, synthetic and glycosylation agent. It can be used as a monosaccharide or oligosaccharide for the synthesis of complex carbohydrates.

7-Deoxy-1,2:4,5-di-O-isopropylidene-L-glycero-D-glucoheptitol is a high purity synthetic compound that can be custom synthesized to order. It is a white powder with a molecular weight of 264.27 grams per mole and is soluble in water and DMSO. The CAS No. for this compound is 2206188-76-3. It has been fluorinated at the C2 position and has been modified with a click chemistry reaction to create an oligosaccharide or polysaccharide. This product is available for purchase from our store at www.sigmaaldrichchemicals.com/7deoxy1,2:4,5diOisopropylideneLglyceroDglucoheptitol

(2S, 3S, 4S) -4- (Hydroxymethyl) - N- methyl- 3- (phenylmethoxy) - 1- (phenylmethyl) -2- azetidinecarboxamide is a synthetic glycosylinase inhibitor. It is an Oligosaccharide which contains a sugar and a saccharide. The synthesis of this product can be customized according to the customer's needs. This product has been fluorinated and custom synthesized. It is a high purity, complex carbohydrate with click modification.

Isorhamnetin 3-glucoside-7-rhamnoside is a type of flavonoid that is found in plants and has the chemical formula C14H12O5. It is a glycoside that is converted to its aglycone, rhamnetin, in the body. Isorhamnetin 3-glucoside-7-rhamnoside has shown potential as an antiinflammatory agent by inhibiting the ubiquitin proteasome pathway and Cox2 inhibitory activity. It also inhibits protease activity and can be used to treat inflammatory diseases such as arthritis. Isorhamnetin 3-glucoside-7-rhamnoside is synergistic with other molecules, so it can be used to prevent or treat inflammation when combined with other drugs.

Uridine plays a vital role in the glycolysis pathway of galactose. It is used as a precursor in the production of CDP-choline. It is an important nutrient and widely used as a dietary supplement. It improves brain cholinergic functions and hepatic mitochondrial function in certain liver toxins. It plays a major role in pain physiology and brain energy utilization to maintain ATP production under restricted oxygen conditions. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2,5-Anhydro-3-deoxy-D-xylo-hexonic acid 1-propyl ester is a modification of the oligosaccharide xylan. The compound has been synthesized using chemical methods and can be used as a raw material in the production of other products. 2,5-Anhydro-3-deoxy-D-xylo-hexonic acid 1-propyl ester has been custom synthesized to produce high purity and is available with CAS number. It is a monosaccharide that can be methylated and glycosylated and is a polysaccharide made up of sugars (sucrose, glucose, fructose) with various types of saccharides (sugar).

Heparin is a complex carbohydrate that has been modified by the addition of a sugar and a sulfate group. It is used in the treatment of thrombosis, deep vein thrombosis, pulmonary embolism, and other blood clots. Heparin disaccharide IV-S disodium salt (HDS) is an intravenous form of heparin that consists of sodium salts of two saccharides: heparin disaccharide and sodium disulfate. HDS has been shown to be more potent than unfractionated heparin in animal models, as well as being more effective in preventing clot formation in humans. This drug also exhibits less frequent side effects such as skin rash, itching, or hives.

1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose is a synthetic sugar that is used in the synthesis of oligosaccharides and saccharides. It can be used to synthesize glycosyl groups by methylation or modification. This product has been shown to be useful in the synthesis of complex carbohydrates. 1,2,O-Isopropylidene-6-O-methylsulfonyl-a-D-glucofuranose has a purity of >99%.

Rhodamine dextran (RD) is widely used as both an anterograde and retrograde tracer in neurons and for numerous other applications. It is biologically rather inert having α-1,6-linked glucose residues resistant to cleavage by most endogenous cellular glycosidases. It has low immunogenicity and makes an ideal long-term tracer for live cells. RD also serves as a valuable marker for cell loading of macromolecules by micro-injection, vesicular fusion, and electroporation, as well as for the uptake and internal processing of exogenous materials by phagocytotic and endocytic pathways.

Decyl a- D- glucopyranoside is a synthetic, custom-synthesized carbohydrate and sugar that is used in the synthesis of oligosaccharides. This compound is also used in the synthesis of saccharides and glycosylations. Decyl a- D- glucopyranoside has high purity and can be modified with fluorination, methylation, or glycosylation to produce desired products.

Di-a-D-galactosyl-mannopentaose is a mannopentaose derivative that has been modified with a methyl group at the C2 position and fluorinated at the C6 position. This compound can be used as an intermediate in the production of oligosaccharides and polysaccharides, which are complex carbohydrates that contain many sugar molecules. The product is of high purity, with no detectable impurities. It was synthesized using a custom synthesis approach, which allows for modification of the chemical structure to produce desired properties. This product is stable when stored at room temperature and does not require refrigeration. It does not contain any organic solvents or volatile compounds and is free from endotoxins or heavy metals.

α-1,4-glucododecasaccharide derived from starch by hydrolysis and chromatography

DEAE-Dextran hydrochloride (DEAE-D) is a positively-charged dextran derivative that can be used for vaccine production, gene therapy, protein stabilisation, dyslipidemia prevention, as flocculating agent, and many other applications. DEAE-D is also used for transfecting animal cells with foreign DNA.  DEAE-Sepharose, DEAE-650 and DEAE-Sephadex are commonly used in chromatography for the separation of biological molecules such as proteins and carbohydrates.

Inhibits the Maillard reaction between glucose and glycine

Allyl 2-acetamido-4,6,-O-benzylidene-2-deoxy-a-D-glucopyranoside is a sugar that is used as a custom synthesis or modification. It is also called allyl 2-(1,3-dioxo-1,3,4,-thiadiazolidinium)acetamido 4,6,-O-(benzylidene)-2 deoxy erythro -a D glucopyranoside. Allyl 2 acetamido 4,6,-O -benzylidene -2 deoxy erythro -a D glucopyranoside is used in the glycosylation of proteins and oligosaccharides and in the synthesis of saccharides. This compound has been shown to be useful in identifying glycosaminoglycan chains in complex carbohydrates.