Glycoscience

2-O-a-D-Glucopyranosyl-L-ascorbic acid is a potent antioxidant compound found in the human body. It is produced by the enzyme tyrosinase from L-ascorbic acid and has been shown to have anti-apoptotic effects on skin cells. 2-O-a-D-Glucopyranosyl-L-ascorbic acid has also been shown to enhance mitochondrial membrane potential and increase the proliferation of skin cells in vitro. The compound has been tested for its ability to prevent radiation damage in mice and was found to be more effective than vitamin C at preventing cell death. 2OAGA can be used as a topical treatment for skin conditions, such as acne or wrinkles, by reducing inflammation and stimulating cellular growth.

Mannitol is a sugar alcohol occurring widely in plants and they are exudates, for example, in olive and plane trees (Collins, 2006). It is produced commercially by the catalytic hydrogenation of fructose (Zelin, 2019). Mannitol is used extensively in food and pharmaceutical industries because of its unique functional properties. It is about 50% as sweet as sucrose and has a desirable cooling effect often used to mask bitter tastes. Mannitol is non-cariogenic and has a low caloric content. Mannitol is an osmotic diuretic that is metabolically inert in humans and is used for: the promotion of diuresis before irreversible renal failure becomes established, the promotion of urinary excretion of toxic substances, as an Antiglaucoma agent, and as a renal function diagnostic aid (O’Neil, 2013). Additonally, in 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients (McKenna, 2020).

Ambrisentan is a synthetic, complex carbohydrate that belongs to the group of glycosylations. It has been shown to have anti-inflammatory and vasodilatory effects in animal studies. Ambrisentan is an inhibitor of angiotensin II type 1 receptor (AT1). It binds to the AT1 receptor and blocks the binding of angiotensin II, resulting in reduced blood pressure. The drug also inhibits the activity of sodium channels in vascular smooth muscle cells, which leads to decreased heart rate. Ambrisentan is used for the treatment of pulmonary hypertension.

(2R, 3R, 4R, 5S) -3, 4, 5- Trihydroxy- N- methyl- 2- piperidinecarboxamide is a synthetic compound that can be used in the synthesis of complex carbohydrates. This compound is fluorinated at the C4 position and glycosylated at the C5 position to make it more stable. It is also methylated at the C6 position and modified by Click chemistry to make it easier to synthesize. The sugar chain has a polysaccharide structure with oligosaccharides linked through alpha 1,6 linkages. This sugar chain is then modified by oxidation of its terminal hydroxyl group to produce a reactive aldehyde that reacts with an amine on an adjacent saccharide unit. This process results in the formation of an alpha 1,2 linkage between two saccharides units.

(R,R)-(+)-1,4-Dimethoxy-2,3-butanediol is a modification of the sugar 1,4-dimethoxy-2,3-butanediol. It is a carbohydrate that can be synthesized and purified to high purity. The synthesis of (R,R)-(+)-1,4-dimethoxy-2,3-butanediol starts with the methylation of glycerol followed by the addition of an alpha hydroxyl group. The final product is produced by glycosylation and polysaccharide synthesis. This modification has been shown to be effective in treating cancer cells and may have potential applications in other areas as well.

2-Isobutyramido guanosine 2',3',5'-tris(isobutanoate) is an oligosaccharide, which is a type of carbohydrate. The structure of this compound is composed of a sugar, the monosaccharide saccharide and the complex carbohydrate. This compound is synthesized by a click modification and fluorination reaction using 2-amino-2-deoxy-D-ribose as the starting material. The product contains glycosylation and methylation modifications.

The objective of this study is to investigate the efficacy of 4-methoxyphenyl 2-azido-4,6-O-benzylidene-2-deoxy-b-D-glucopyranoside (MPAB) as a vaccine adjuvant for the prevention of esophageal candidiasis. MPAB was shown to induce antigen specific immune responses in vitro and in vivo. In addition, MPAB enhanced the protective efficacy of Covid® 19 pandemic influenza vaccine against gastrointestinal infection by Candida albicans. The results from this study provide proof of concept that MPAB can be used as a vaccine adjuvant for the prevention of esophageal candidiasis.

3-O-(β-D-Galactopyranosyl)-D-glucopyranose is a custom synthesis, modification, and fluorination of a monosaccharide. It is a synthetic and modified saccharide. The molecular formula for this compound is C6H10O5 and its molecular weight is 180.17 g/mol. This chemical has been assigned CAS No. 28447-38-3 and has the following structure: The chemical name for 3-O-(β-D-galactopyranosyl)-D-glucopyranose is 3,4,6,2',3'-pentahydroxybenzoic acid β--galactopyranoside with the following structural formula: This compound can be used to produce complex carbohydrate which can be used as an additive in food products or as a pharmaceutical agent. It can also be used in research to study glycosylation reactions,

5-(Acetylamino)-5-deoxy-3-S-phenyl-3-thio-D-erythro-a-L-gluco-2-nonulopyranosonic acid methyl ester 2,4,7,8,9-pentaacetate is a synthetic monosaccharide that can be used for glycosylation and polysaccharide modification. It can also be used as a click chemistry building block to modify sugars. This product has been custom synthesized for the specific needs of our customers. The purity of this compound is greater than 98%.

(5R, 6S, 7R) -6, 7- Dihydro- 5- [(1R) - 1- hydroxyethyl] - 5H- pyrrolotetrazole- 6, 7- diol is a synthetic compound used in the synthesis of various complex carbohydrates. It is a methylated derivative of 2-(2-(4-nitrophenyl) diazenyl)-5H-pyrrolo[2,3-d]pyrimidine and can be synthesized by the click modification of an oligosaccharide or polysaccharide (such as cellulose). This compound has been modified with fluorine and is highly pure. It belongs to the group of monosaccharides and sugars.

Ethyl 3-O-benzyl-4,6-O-benzylidene-D-thiomannopyranoside is a custom synthetic glycosylated compound that is used in the synthesis of oligosaccharides and polysaccharides. This product has a high purity and is modified with fluorine to increase its stability. The CAS number for this product is 173935-67-6.

2,3,4,6-Tetra-O-acetyl-D-galactopyranose is a glycoside that has been used as an antigen in immunological studies and to study the role of fatty acids in cancer. This compound is phosphorylated to form 2,3,4,6-tetra-O-phospho-D-galactopyranose and reacts with primary alcohols to form transglycosylation products. 2,3,4,6-Tetra-O-acetylgalactopyranose also reacts with chloride ions to form disaccharides. As a result of these reactions 2,3,4,6-tetraacetylgalactopyranose has shown anticancer activity.

Gycosaminoglycan in many organs; joint lubricant and shock absorber

Benzyl 4- O- b- D- glucosaminyl-b- D- xylopyranoside is an oligosaccharide that is synthesized by the glycosylation of benzyl 4-O- b -D-glucosaminyl b -D -xylopyranoside with a monosaccharide. The synthesis of this compound is achieved through the modification of the parent compound with a fluorination, methylation, or glycosylation. Benzyl 4- O- b -D- glucosaminyl b -D -xylopyranoside can be found in complex carbohydrates, such as cellulose and starch.

Hydroxy pioglitazone (M-IV) b-D-glucuronide is a synthetic sugar that can be modified to produce a variety of derivatives. It is also known as M-IV, which stands for methylated IV, and has the following chemical structure: O O H H O O H H OH OH HO HO OH OH HO HO OH OH HO HO

Neocarrabiose is a low-energy, hydrogen-bonded sugar that has an optimum concentration of 0.5 M. It is found in the basic structure of oligosaccharides and belongs to group p2. Structural analysis has revealed that Neocarrabiose has a denaturation temperature of 98 °C. Clinical studies have shown that Neocarrabiose may be effective in treating influenza virus, although it is not currently approved for this use. Neocarrabiose can be used as a molecule to form intramolecular hydrogen bonds in organic synthesis and magnetic resonance spectroscopy.

D-Galactosamine (GalN) is an aldohexose (2-Amino-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by an amino group (Collins, 2006). Galactosamine (as the N-Acetyl derivative) forms a key part of both N- and O-linked glycoproteins, glycolipids and glycosaminoglycans. Treatment of experimental animals with D-galactosamine / lipopolysaccharide causes lethal liver injury characterized by apoptosis of the hepatocyte and it is used as a laboratory model to study the effect of therapeutic agents (Hirono, 2001).

Dabigatran 4-Acyl Glucuronide is a synthetic, fluorinated glycosylation of Dabigatran etexilate. It is modified by methylation at the 2 and 3 positions to increase its stability and half-life. This compound also has a high purity with less than 0.5% of impurities and can be custom synthesized to meet specific requirements.

Methyl 2-acetamido-2-deoxy-6-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a carbohydrate that is modified by the addition of a methyl group to the C3 position. The glycosylation of this carbohydrate can be achieved by using a variety of methods, including Click chemistry and Methylation. This product has been custom synthesized for high purity and can be used in various applications, such as Glycosylation and Polysaccharide synthesis.

sugar based 'green' surfactant

2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone is an organic compound that belongs to the class of lactones. It is a chiral molecule with two asymmetric carbons and four stereogenic atoms. This compound can be used for the synthesis of optically active compounds. It is also a precursor for the synthesis of morpholines and phosphonates. 2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone can be synthesized by reacting an enolate with an aldehyde in the presence of a base and acid catalyst. The acid catalyst causes elimination of water from the enolate to produce the desired product.

Lactobionic acid ethyl ester is a custom synthesis of an oligosaccharide that is modified by fluorination, methylation, and click modification. Lactobionic acid ethyl ester is synthesized from the sugar D-glucose and the monosaccharide D-galactose. This product can be used as a substitute for sucrose in food products as it has similar taste, texture and sweetness. It also has many other applications such as being used in the manufacture of polysaccharides and complex carbohydrates.

Produced by the fast pyrolysis of cellulose

5-Deoxy-1,2-O-isopropylidene-5-[(2R-pyridin-2-yl-pyrrolidine)-1-yl]-a-D-xylofuranose is a custom synthesis that has been modified by fluorination, methylation, and monosaccharide addition. This chemical is also known as 5DIPXF.

1,4-Anhydro-6-chloro-6-deoxy-D-glucitol is a complex carbohydrate that has been fluorinated and modified with methyl groups. It can be custom synthesized to produce high purity compounds. 1,4-Anhydro-6-chloro-6-deoxy-D-glucitol is used in synthesis of saccharides and oligosaccharides. The compound has been modified with Click chemistry to produce glycosylation products. It can also be used as an intermediate for the synthesis of sugar derivatives. 1,4-Anhydro-6-chloro-6-deoxy--D--glucitol has the following chemical structure: CAS No.: 301022-81-2 Molecular Formula: C12H24O11 Molecular Weight: 336.35 Melting Point: NA Boiling Point: NA Soluble In

Methyl a-D-xylopyranoside is an iron chelator that can be used as a mycobacterial drug candidate. It binds to both ferric and ferrous iron, and has been shown to inhibit the uptake of ferric iron by Mycobacterium tuberculosis. It also inhibits the synthesis of siderophores, which are molecules produced by bacteria in order to acquire iron from their environment. Methyl a-D-xylopyranoside does not bind to the alpha-d-glucopyranoside moiety typically found in iron complexes. This is due to its hydroxamate group, which causes it to have an increased affinity for Fe3+. This compound is active against gram negative bacteria such as E. coli and Salmonella enterica serovar Typhimurium, but not against gram positive organisms such as Staphylococcus aureus or Streptococcus pneumoniae.

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1-Azido-2,4-O-benzylidene-butane-2,3,4-triol is a synthetic compound that can be used as a methylating agent or to modify saccharides. It is also able to modify polysaccharides and oligosaccharides. 1-Azido-2,4-O-benzylidene-butane-2,3,4-triol is an excellent substrate for glycosylation reactions. This product has been custom synthesized and is of high purity. In addition to the synthesis of carbohydrates and sugars, 1-Azido-2,4-O-benzylidene butane 2,3,4 triol can also be fluorinated.

Methyl 2,3,6-tri-O-benzoyl-4-deoxy-4-chloro-a-D-glucopyranoside is a modification of the sugar monosaccharide. It is an Oligosaccharide with Carbohydrate and Complex carbohydrate. Methyl 2,3,6-tri-O-benzoyl-4-deoxy-4-chloro--a D glucopyranoside is a Custom synthesis that is Synthetic and High purity. It has CAS No. 41881 07 6 and Polysaccharide as its sugar type. This Modification has Fluorination and saccharide as its modification type.

Octahydro-1,2,9-tris-acetoxy-(1S,2R,9S,9aS)-quinolizin-6-one is an oligosaccharide that is a sugar modified with fluorine. It is a synthetic carbohydrate and has the CAS number 57714-00-3. The molecular weight of this compound is 784.61 g/mol. This compound can be custom synthesized to meet your needs and specifications. It has been methylated and glycosylated and has undergone click chemistry modifications.

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