Glycoscience

D-Maltose 1-phosphate dipotassium salt is a disaccharide that can be used in the synthesis of oligosaccharides and polysaccharides. It is also an excellent candidate for further modification.

Repaglinide is a drug that belongs to the class of drugs called meglitinides. It is used in the treatment of type 2 diabetes mellitus and has been shown to lower blood sugar levels. Repaglinide is metabolized to repaglinide acyl-D-glucuronide, its active form, by esterases in the liver. The majority of this metabolite is excreted in urine as an acyl glucuronide. A small amount of this metabolite is excreted into bile and undergoes enterohepatic circulation, resulting in reabsorption and conjugation with glucuronic acid. This process results in a decrease in the amount of repaglinide acyl-D-glucuronide that circulates through the body and prolongs its activity.

Methyl 1,2,3,4-tetra-O-acetyl-a-L-idopyranuronate is a carbohydrate standard that belongs to the group of L-iduronic acid derivatives. Methyl 1,2,3,4-tetra-O-acetyl-a-L-idopyranuronate is commonly used in the synthesis of glycosides and glycoconjugates. Its fluorescence properties make it useful for labeling and detection purposes in biochemical assays. This compound can also serve as a substrate for enzymes involved in carbohydrate metabolism. Overall, Methyl 1,2,3,4-tetra-O-acetyl-a-L-idopyranuronate is an essential tool for researchers in the field of glycobiology and biochemistry.

2-Acetamido-1,3-di-O-acetyl-2-deoxy-D-glucopyranose is a synthetic sugar that is used in the synthesis of complex carbohydrates. It has been shown to be an effective fluorinating agent for glycosylations and can be methylated or click modified. 2-Acetamido-1,3-di-O-acetyl-2-deoxy-D-glucopyranose has high purity and can be custom synthesized to order.

1-Amino-1,5-dideoxy-L-erythro-2-pentulose is a glycoconjugate that contains an amino sugar. It is also a complex carbohydrate that is methylated and fluorinated. 1-Amino-1,5-dideoxy-L-erythro-2-pentulose is a polysaccharide made up of saccharides and oligosaccharides. The saccharides in this compound are modified with the addition of sugars (e.g., glycosylation). This product has been custom synthesized to order and can be ordered as a high purity product.

α,β-Trehalose is a carbohydrate that is found in many organisms and has been shown to have biochemical properties such as energy metabolism, enzyme activities, and x-ray diffraction data. Trehalose has a phase transition temperature of around 98°C, which makes it an ideal sugar for food preservation. Trehalose can also be used as a sugar substitute with the same sweetness level as sucrose. The chemical stability of trehalose allows it to be used as a preservative in food and beverages. Trehalose has been shown to be nontoxic in animal studies with doses up to 2000 mg/kg body weight. It also has an optimum pH of 7 and is stable at high temperatures.

3,4-Di-O-acetyl-L-arabinal is a synthetic compound that belongs to the class of monofluorides. It has been synthesized from l-arabinose by a stereoselective process, with triflic acid as the catalyst and propargylation as the key step. The synthetic pathway starts from an acid hydrolysis of L-arabinose to yield 3,4-di-O-acetyl-L-arabinonic acid. This acid is then converted to 3,4 diacetyl L arabinonic acid with acetic anhydride and acetic acid in the presence of triethylamine. The final product is then obtained by reacting this intermediate with 1 equivalent of sodium fluoride in tetrahydrofuran (THF) using catalytic reduction with sodium borohydride at 0 °C. The major advantage of this synthetic process is that it provides two stereoisomers: (

2-Amino-2-deoxy-D-ribose hydrochloride is a synthetic sugar that can be used to produce oligosaccharides and polysaccharides. It has been shown to have high purity and to be custom synthesized as per requirements. This sugar can also be modified with fluorination, methylation, or click modification.

3,4,6-Tri-O-benzyl-D-glucal is a benzyl protected, 2,3 unsaturated glucal used as a chiral intermediate. The C2-C3 double bond of the pyranose ring can be modified via a variety of reactions including: hydrogenation, oxidation, hydroxylation, and aminohydroxylation, to generate structural complexity. 3,4,6-Tri-O-benzyl-D-glucal also minimizes tedious protecting-group strategies required for fully oxygenated sugars. The products of 2,3 unsaturated glycosides as chiral intermediates have played a role in the synthesis of many biologically active compounds, such as, nucleosides and modified sugar derivatives.

Flavanone rhamnoglucoside is a specialized flavonoid compound, which is derived from various natural sources such as fruits, vegetables, and certain medicinal plants. It functions primarily as an antioxidant by scavenging free radicals, thereby protecting cells from oxidative stress. Additionally, it exhibits anti-inflammatory properties by modulating pathways involved in inflammation, such as NF-kB and COX-2. This compound is of interest in pharmacological research due to its potential therapeutic benefits. It is explored for applications in treating conditions associated with oxidative stress and inflammation, such as cardiovascular diseases, diabetes, and neurodegenerative disorders. Flavanone rhamnoglucoside is also investigated for its potential in enhancing skin health and protecting against UV-induced damage. Its multifaceted role in biological systems makes it a subject of considerable interest in the development of new therapeutic strategies and nutraceutical products.

The tetrasaccharide 1,2-ethanediol is a synthetic compound that is used in pharmaceuticals and as an intermediate for other compounds. This product is a high purity custom synthesis that can be used for methylation or glycosylation reactions. The CAS number for this product is 615-86-1.

a-L-Galactose-1-phosphate dipotassium salt is an oligosaccharide that can be prepared by the methylation of a galactose molecule. It is a synthetic compound that has been shown to have antiviral properties. The modification of the sugar structure with fluorine atoms increases the stability of the molecule and prevents its degradation. This product is soluble in water and can be used as a pharmaceutical intermediate for other compounds.

Isosaccharinic acid is a bacterial strain that produces isosaccharinic acid as its main fatty acid. The thermodynamic data for the reaction mechanism of the conversion of glucose to isosaccharinic acid has been determined. Isosaccharinic acid formation is catalyzed by an enzyme called glycosyl-glycerate dehydrogenase, which converts glycerate to 3-hydroxypropanoic acid and then to 3-oxopropanoate before it undergoes decarboxylation and reduction to form isosaccharinic acid. Radionuclides such as TcO4 are used in chemical ionization mass spectrometry for the detection of this compound in samples. Neutral pH, high activation energies, and low binding constants are all factors that affect the stability of this molecule.

6-Azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide that is CAS No. 65371-16-6. It is a sugar or Carbohydrate and complex carbohydrate.

3,6-Di-O-triisopropylsilyl-D-galactal is a synthetic sugar that is used as a reagent for glycosylation. It has been shown to react with the aldehyde group of an alcohol to form an acetal. The product can be hydrolyzed under acidic conditions to release the desired sugar product. 3,6-Di-O-triisopropylsilyl-D-galactal is soluble in water and ethanol and has CAS number 201053-37-4.

N-Acetyl-9-O-(N-acetyl-a-neuraminosyl)-neuraminic acid is a synthetic, fluorinated monosaccharide that is used in the synthesis of glycosides and polysaccharides. It can be custom synthesized to any desired purity. This chemical has many modifications, including methylation, esterification, and glycosylation. The CAS number for this product is 96425-77-3.

Applications Carbon 13 labelled analogue of N-Acetylneuraminic acid (A187000). References Methods Enzymol., 5, 391 (1962), Biochemistry, 18, 2086 (1979)