Enzyme, Peptide and Protein Related Compounds

Please enquire for more information about Big Endothelin-1 fragment (22-38) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Morantel citrate is a drug that belongs to the class of anthelmintics. It works by inhibiting the membrane system in nematodes, which leads to paralysis and death. Morantel citrate has been shown to be effective against Ostertagia ostertagi, Ancylostoma caninum, and Uncinaria stenocephala. Morantel citrate is not active against nematode species that are resistant to anthelmintics (e.g., Ascaris suum). The oral dose of morantel citrate for cattle is 0.5-1 mg/kg and for sheep 1-2 mg/kg body weight. This drug is poorly absorbed from the gastrointestinal tract and only about 10% of the dose reaches systemic circulation. Morantel citrate is metabolized in the liver by cytochrome P450 enzymes and excreted in urine as metabolites or unchanged drug.

Please enquire for more information about N-alpha-Acetyl-L-lysine 7-amido-4-methylcoumarin acetate salt hemihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (Asp56)-pTH (1-84) (rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Orexin A (human) TFA is a high quality reagent that can be used as an intermediate in the synthesis of complex compounds, useful for research and development. It has many potential uses, including as a fine chemical, speciality chemical and reaction component. Orexin A (human) TFA is a versatile building block with many applications, such as being a useful scaffold or building block in reactions where it can be used in the synthesis of other compounds. It is also a valuable research chemical that can be used to study orexin receptors and their ligands.

Please enquire for more information about Tyr-alpha-CGRP (23-37) (mouse, rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Trifluoroacetate salt

Resveratrol is a natural phenylpropanoid of the family of stilbenoids and is present in red wines and certain foods. Resveratrol has been deeply studied for its antioxidant, anti-inflammatory and antimicrobial properties. In Vero cells, resveratrol at 50 ÎŒM has shown to have the ability to inhibit SARS-CoV-2 replication by 98% when added after infection. Featured reference paper: Rossi et al, 2021; Yang et al, 2021.

Please enquire for more information about Band 3 Protein (824-829) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about RFRP-3 (rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-HT2A serotonin receptor antagonist

4-Butanoyloxybenzenediazonium Tetrafluoroborate is a fluoroborate that has discriminative properties. It is used in the determination of butyrylcholinesterase activity and to study the environment of the active site. 4-Butanoyloxybenzenediazonium Tetrafluoroborate reacts with propidium to form an affinity label, which can be detected by measuring fluorescence intensity. The binding site on acetylcholinesterase is positioned at the side of the enzyme opposite to the substrate (a quaternary ammonium salt). Inactivation occurs when pH levels are too high or too low. This inhibitor also binds to a region on the enzyme other than its active site, which prevents acetylcholine from binding and hydrolyzing choline esters.

Potassium (bromomethyl)trifluoroborate is a boronic acid compound that has been used as an amide coupling agent. It is a potassium salt of the trifluoroborate ion, which can be produced by reacting methyltriphenylborane with potassium bromide. Potassium (bromomethyl)trifluoroborate is used in cross-coupling reactions to form amides from primary amines and aryl chlorides. The functional groups on the molecule include carboxylic acid, alcohol, ester, ether, and chloride. Potassium (bromomethyl)trifluoroborate can be synthesized from the reaction of kallikrein with chlorides or amines.

Please enquire for more information about VIP sulfoxide (human, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Caffeine citrate is a low-dose caffeine product that has been shown to increase locomotor activity in rats. Caffeine citrate is an ester of caffeine and citric acid. It inhibits the enzyme that breaks down acetylcholine, which may lead to an increase in brain functions. Caffeine citrate is used as a treatment for apnea in pediatric patients, and it has also been shown to prevent bacterial translocation and reduce liver impairment caused by certain drugs. The therapeutic effect of caffeine citrate may be due to its ability to inhibit mitochondrial membrane potential, or its effects on basic proteins such as sodium citrate, or both.

Erythromycinacistrate is a macrolide antibiotic, which is derived from the bacterium *Saccharopolyspora erythraea*. Its mode of action involves binding to the 50S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis. This action effectively halts bacterial growth and replication, making it particularly effective against a wide range of Gram-positive and some Gram-negative bacteria. The primary uses and applications of Erythromycinacistrate involve the treatment of various bacterial infections such as respiratory tract infections, skin infections, and sexually transmitted infections, including those caused by *Mycoplasma* and *Chlamydia* species. Due to its mechanism of disrupting bacterial protein synthesis, it is often employed in clinical settings where alternative antibiotics are ineffective or contraindicated. Understanding its molecular interactions and synthesis pathways can provide insights into antibiotic resistance mechanisms and aid in the development of new antibacterial strategies.

Please enquire for more information about Acetyl-ACTH (4-24) (human, bovine, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Benzhydrylpiperazine hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Endothelin-1 (ET-1) is a peptide that is produced by the endothelium. ET-1 is involved in numerous biological processes, including vasoconstriction, inflammation, and cell proliferation. Endothelin-1 (human ET-1) acetate salt H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-(Glu)-Cys-(Val)-Tyr-(Phe)-Cys-(His)-Leu -Asp(-Ile)-Ile(-Trp)) acetate salt is a recombinant protein that has been shown to significantly upregulate the production of endothelin in primary pulmonary hypertension. It also plays an important role in bowel disease, where it may be involved in the development of chronic inflammatory bowel disease.

Please enquire for more information about Leptin (138-167) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about MCH-Gene-Overprinted-Polypeptide-14 (rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Methyl 2-hydroxyisobutyrate (MHIBA) is a compound that is found in nature. It has been synthetically produced by reacting formamide with dibutyltin oxide. The reaction of MHIBA with magnesium leads to the formation of a lamellar phase, which is an ordered structure composed of layers of molecules. The mass spectrometric analysis of this compound reveals the presence of a hydroxy group and an acetaldehyde group, as well as a hydrogen bond between the two. The dehydration reaction time for this molecule is between 3 and 5 minutes at 100 degrees Celsius.

Diethylcarbamazine citrate is an anthelmintic drug that is used to treat helminth infections. It inhibits the growth of nematodes by binding to the polymerase chain and inhibiting protein synthesis. Diethylcarbamazine citrate has been shown to be effective in treating bowel disease, which may be due to its ability to inhibit inhibitor molecules. This drug also has low potency for a number of bacterial species, such as Escherichia coli, Klebsiella pneumoniae, and Bacillus cereus, making it a good choice for use in vitro assays. Diethylcarbamazine citrate has a pyrazole ring in its structure that can be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase or conjugated with glucuronic acid.

Amylin is a peptide hormone that belongs to the group of hormones that include insulin and glucagon. Amylin has been shown to have an anti-diabetic effect in diabetic patients by stimulating insulin secretion and improving insulin sensitivity. Amylin inhibits protein aggregation, which may be due to its ability to form hydrogen bonds with other amyloid protein molecules. The structural biology of amylin has been studied using NMR spectroscopy and silver ions. This molecule has a sequence of H-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser, with a molecular weight of 3,726 Da.

Acetate salt

Please enquire for more information about (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Potassium [(4-phenylaminomethyl)phenyl]trifluoroborate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Annexin A1 (1-11) is a peptide that is part of the annexin family. It is involved in the degranulation of cells and inhibits inflammation by inhibiting the production of pro-inflammatory cytokines. Annexin A1 (1-11) has been shown to be an anti-inflammatory compound as it binds to phospholipids on the surface of neutrophils, leading to inhibition of their chemotaxis and phagocytosis. This peptide also interacts with other annexins and prevents apoptosis by blocking caspase activity. Finally, it has been found that annexin A1 (1-11) can promote the healing of wounds in mice by accelerating reepithelialization and reducing scar formation. The concentration required for these effects are nanomolar concentrations.

Please enquire for more information about Z-D-aspartic acid beta-tert-butyl ester hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Sulfo-N-succinimidyl 4-maleimidobutyrate sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Trifluoroacetate salt

1-Butyl-1-methylpyrrolidinium tetrafluoroborate is an organic solvent that can be used as a hydrogen bond donor. It has been shown to have a kinetic inhibitory effect on the growth of adiponitrile in acidic environments. This compound also has the ability to form hydrogen bonds with protonated carboxylic acids, which are abundant in fatty acids, and their salts. This property makes 1BMPBF highly effective for inhibiting the growth of bacteria in high salt environments. 1BMPBF has been observed to exhibit potentiodynamic polarization, which is an electrochemical technique that can be used to measure the activity of an electrode.

Inhibitor of protein synthesis; aminocyclitol class

4-Isopropyl-4'-methyldiphenyliodonium tetrakis(pentafluorophenyl)borate (DMP-BF4) is a diode that can be used in solar cells. It is a reactive molecule that initiates polymerization reactions and also functions as an irradiation source for polymerizing silicones, polyolefins, and oxetane. DMP-BF4 has shown to be an efficient initiator for cationic polymerization of diethylene glycol methyl ether methacrylate (DEGMA).

Glycyl-L-Glutamine is a dietary supplement that provides the body with glutamine. It is a naturally occurring amino acid and is involved in protein synthesis, antibody production, and cell growth. Glycyl-L-Glutamine has been shown to inhibit bacterial translocation by maintaining physiological levels of glutamine in the body. The drug also stimulates IL-2 receptor expression and upregulates T cells, which are important for immune function. Glycyl-L-Glutamine has been shown to have a hypotensive effect on systolic pressure in mice. This may be due to its ability to maintain mitochondrial membrane potential and promote energy metabolism. Glycyl-L-Glutamine also binds to peptide hormones such as insulin, glucagon, and somatostatin and can be used as an analytical method for detecting these hormones.

5-Chloro-1-methylimidazole nitrate (5C1MN) is a synthetic chemical that has been used as an intermediate in the synthesis of other chemicals. 5C1MN is made by reacting methylamine with nitric acid in acetone solution. The reaction proceeds via two steps: first, cyclization to form the nitrosoiminoacetate followed by nitration to produce 5C1MN. Nitration is an important step because it converts the amine groups into reactive nitro groups. The product, 5C1MN, is a white crystalline solid that can be used as a precursor for other compounds.

Please enquire for more information about (Phe1,Ser2,Tyr6)-PAR-1 (1-6) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Biogenic polyamine; NMDA glutamate receptor agonist/antagonist

HIV Protease Substrate VIII is a peptide that belongs to the HIV protease family. It is an active site residue of the HIV protease and has been shown to be essential for catalysis. The substrate binds to the aspartyl-proline termini, which are critical in preventing spontaneous hydrolysis of the amide bond. This peptide has also been used as an active analog to study HIV protease activity and as a model for developing new drugs with improved specificity and stability.

Please enquire for more information about Potassium9-(2,3-dimethyl-2-butoxy)-9-boratabicyclo[3.3.1]nonane including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Acetyl-(Cys(Acm)33·42)-EGF (33-42) amide (mouse) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Lithium difluoro(oxalato)borate is an electron-microscopic corrosion inhibitor that belongs to the class of ester compounds. It is a solid compound that has been shown to be efficacious against oxidation products. The efficiency of this compound is dependent on the concentration and purity of lithium difluoro(oxalato)borate and the type of metal, such as steel or aluminum. Lithium difluoro(oxalato)borate can be used in rechargeable batteries, due to its transport properties, high salt tolerance, and low self-discharge rate. This compound has been shown to have functional groups that are capable of interacting with hydrogen fluoride in an organic solution.

Please enquire for more information about Melanin Concentrating Hormone, salmon MCH, salmon including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Biotinyl-BNP-32 (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page