Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Products of "Antiparasitics"
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DHFR-IN-20
DHFR-IN-20 (Compound LA1) is an inhibitor of dihydrofolate reductase (DHFR) targeting the malignant strains of the malaria parasite. It exhibits inhibition constants (Kis) of 0.16 nM, 0.30 nM, and 6.6 nM for PfDHFR-WT, PfDHFR-QM, and HsDHFR, respectively. Additionally, DHFR-IN-20 demonstrates antimalarial activity, with IC50 values of 1.4 nM against parasites carrying the wild-type (TM4/8.2) PfDHFR enzyme and 1.6 μM against those with the quadruple mutation (V1/S)PfDHFR.Color and Shape:Odour SolidBenzeneacetonitrile, 2,6-dichloro-α-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-
CAS:Formula:C17H9Cl3N4O2Purity:98%Color and Shape:SolidMolecular weight:407.637967-Chloro-3-iodo Hydroxychloroquine
CAS:Controlled ProductFormula:C18H25ClIN3OColor and Shape:NeatMolecular weight:461.77DHFR-IN-3
CAS:DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.Formula:C8H7BrN4Purity:99.59% - 99.61%Color and Shape:SolidMolecular weight:239.07LN002
CAS:LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Formula:C22H15N7Color and Shape:SolidMolecular weight:377.40Antileishmanial agent-19
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L.Formula:C22H18N4O3Purity:98%Color and Shape:SolidMolecular weight:386.4DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Formula:C21H24Cl2N6O2SPurity:97.8% - 99.76%Color and Shape:SolidMolecular weight:495.43Ref: TM-T27135
1mg96.00€5mg279.00€10mg420.00€25mg682.00€50mg947.00€100mg1,301.00€200mg1,738.00€1mL*10mM (DMSO)305.00€Primaquine diphosphate
CAS:Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties.Formula:C15H21N3O·2H3PO4Purity:98.06% - 99.73%Color and Shape:Orange PowderMolecular weight:455.34Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Formula:C17H16F6N2OPurity:99.97%Color and Shape:SolidMolecular weight:378.31Ref: TM-T0860L
1mg70.00€5mg154.00€10mg225.00€25mg376.00€50mg538.00€100mg755.00€200mg1,017.00€1mL*10mM (DMSO)160.00€3-Chloro-N-(3-methoxyphenyl)propanamide
CAS:Controlled ProductApplications 3-Chloro-N-(3-methoxyphenyl)propanamide acts as an inhibitor towards DOXP-reductoisomerase (DXR), a primary target for antimalarial drugs. References Bodill, T. et al.: Bioorg. Med. Chem., 21, 4332 (2013);Formula:C10H12ClNO2Color and Shape:NeatMolecular weight:213.66Niclosamide
CAS:Formula:C13H8Cl2N2O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:327.12Rafoxanide, Vetranal
CAS:Formula:C19H11Cl2I2NO3Purity:99%Color and Shape:SolidMolecular weight:626.0105Metronidazole acetic acid
CAS:Metronidazole acetic acid, a mutagenic metabolite of an antibiotic, targets protozoa and anaerobic bacteria.Formula:C6H7N3O4Purity:98%Color and Shape:SolidMolecular weight:185.1375Didesethyl Chloroquine Hydroxyacetamide
CAS:Controlled ProductApplications An intermediate in the preparation of Cletoquine Oxalate It is a COVID19-related research product.Formula:C16H20ClN3O2Color and Shape:NeatMolecular weight:321.80SDZ285428
CAS:SDZ285428 is a CYP24A1 inhibitor.Formula:C24H20ClN3OPurity:97.51%Color and Shape:SolidMolecular weight:401.89Ref: TM-T4188
2mg37.00€5mg52.00€10mg90.00€25mg170.00€50mg255.00€100mg375.00€200mg533.00€1mL*10mM (DMSO)58.00€1-Piperazinecarboxamide, N,N-diethyl-4-methyl-
CAS:Formula:C10H21N3OPurity:97%Color and Shape:SolidMolecular weight:199.29324000000003Rafoxanide
CAS:Anthelmintic; anti-parasiticFormula:C19H11Cl2I2NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:626.01 g/molMorantel tartrate
CAS:Morantel tartrate (CP-12009-18 tartrate) is an antinematodal agent used mainly for livestock.Formula:C16H22N2O6SPurity:99.86%Color and Shape:White Or Pale Yellow Crystalline PowderMolecular weight:370.42Modoflaner
CAS:Modoflaner is an antiparasitic (veterinary use).Formula:C23H10F12IN3O2Purity:98.4%Color and Shape:SolidMolecular weight:715.232-Methyl-5-nitroimidazole-1-ethanol
CAS:Formula:C6H9N3O3Purity:>99.0%(GC)(T)Color and Shape:White to Orange to Green powder to crystalMolecular weight:171.161H-Imidazole-1-ethanol, α-(chloromethyl)-2-methyl-5-nitro-
CAS:Formula:C7H10ClN3O3Purity:98%Color and Shape:SolidMolecular weight:219.6256Rafoxanide
CAS:Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer.Formula:C19H11Cl2I2NO3Purity:99.47%Color and Shape:Slight Yellowish Brown Injectable Solution &White Oral SolutionMolecular weight:626.0113,21-Dihydroeurycomanone
CAS:13,21-Dihydroeurycomanone (Pasakbumin C) is a natural product isolated from the root of Eurycoma longifolia with antiparasitic activity such as PlasmodiumFormula:C20H26O9Purity:98.01%Color and Shape:SolidMolecular weight:410.42Benzoic acid, 4-(acetylamino)-2-ethoxy-, methyl ester
CAS:Formula:C12H15NO4Purity:98%Color and Shape:SolidMolecular weight:237.2518Paromomycin Sulfate
CAS:Paromomycin Sulfate, an aminoglycoside antibiotic, binds to 30S ribosomes, disrupting protein synthesis and killing bacteria.Formula:C23H47N5O18SPurity:99.73% - 99.86%Color and Shape:SolidMolecular weight:713.71Diethylcarbamazine citrate
CAS:Formula:C16H29N3O8Purity:98%Color and Shape:SolidMolecular weight:391.4168Notrilobolide
CAS:Notrilobolide, an alkaloid with insecticidal properties, is isolated from sweet potatoes and impedes larval development in pests such as Tribolium castaneum.Formula:C26H36O10Purity:98%Color and Shape:SolidMolecular weight:508.56Cycloguanil Hydrochloride
CAS:Formula:C11H14ClN5·HClPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:288.18Ornidazole
CAS:Ornidazole (Tiberal) is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections.Formula:C7H10ClN3O3Purity:99.47%Color and Shape:Crystalline SolidMolecular weight:219.63Pyriproxyfen
CAS:Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.Formula:C20H19NO3Purity:99.87%Color and Shape:Solid CompactMolecular weight:321.37Antitrypanosomal agent 17
Compound 17 (Compd 7a) exhibits potent antiamastigote activity, demonstrated by its IC50 value of 0.03 μM against the T. congolense strain IL3000 [1].Purity:98%Color and Shape:Odour SolidImidocarb dipropionate
CAS:Formula:C25H32N6O5Purity:95%Color and Shape:SolidMolecular weight:496.55885-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole
CAS:3-Br-isoxazoline-based inhibitor for Plasmodium and Leishmania; IC50: 0.035-7.5 μM.Formula:C15H16BrN3O2Purity:99.58%Color and Shape:SolidMolecular weight:350.21Ref: TM-T9858
1mg77.00€5mg155.00€10mg220.00€25mg338.00€50mg472.00€100mg632.00€200mg853.00€1mL*10mM (DMSO)160.00€(2E)-5-Hydroxy-2-pentenoic Acid Methyl Ester
CAS:Controlled ProductFormula:C6H10O3Color and Shape:NeatMolecular weight:130.14AP-C5
CAS:AP-C5 inhibits cGKII with a Pic50 of 7.2, useful in diarrheal disease research.Formula:C16H13N5Purity:99.19%Color and Shape:SolidMolecular weight:275.31N-(2-Hydroxypropyl)methacrylamide
CAS:N-(2-Hydroxypropyl)methacrylamide is used in the synthesis of copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis.Formula:C7H13NO2Purity:98.84%Color and Shape:SolidMolecular weight:143.18Oxibendazole
CAS:Formula:C12H15N3O3Purity:>98.0%(HPLC)(N)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:249.27Antimalarial agent 29
CAS:Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P.Formula:C18H10ClF3N2Purity:98%Color and Shape:SolidMolecular weight:346.73YCN47284
CAS:YCN47284 is an antimalarial compound with an IC50 of 1 μM for P. falciparum.Formula:C10H16Cl2N8Purity:99.52%Color and Shape:SolidMolecular weight:319.19Ref: TM-T9591
1mg35.00€5mg64.00€10mg104.00€25mg182.00€50mg284.00€100mg411.00€200mg585.00€1mL*10mM (DMSO)90.00€Dodecamethylpentasiloxane
CAS:Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil.Formula:C12H36O4Si5Purity:97.62%Color and Shape:SolidMolecular weight:384.84Palmatine chloride
CAS:Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Formula:C21H22ClNO4Purity:97.9% - 99.47%Color and Shape:SolidMolecular weight:387.857Chloroquine diphosphate
CAS:Controlled ProductChloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Chloroquine i a schizonticidal agent and is a widely prescribed antimalarial compound. The antiviral activity of chloroquine in vitro has been reported in 1960’s and recent publications have brought attention to its possible benefits in the treatment of COVID-19 patients, infected with the newly emerged coronavirus (SARS-CoV-2). Current evidence shows that chloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the S-glycoprotein.Formula:C18H32ClN3O8P2Color and Shape:White Off-White PowderMolecular weight:515.86 g/molAntimalarial agent 33
Antimalarial agent 33 (compound 5g) exhibits antiplasmodial activity targeting both erythrocytic and hepatic stages of Plasmodium, with an effectivePurity:98%Color and Shape:Odour SolidTafenoquine
CAS:Tafenoquine (WR 238605) is an antimalarial prophylactic agent with schizonticidal activity, useful in hemolytic anemia research.Formula:C24H28F3N3O3Purity:99.56%Color and Shape:SolidMolecular weight:463.49Insecticidal agent 6
CAS:Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.Formula:C19H14BrCl2N5O4Purity:98%Color and Shape:SolidMolecular weight:527.16Tetramisole Hydrochloride
CAS:Formula:C11H12N2S·HClPurity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:240.75Cordysinin C/D
CAS:Cordysinin C/D (compound 9) is a potential antimalarial agent that effectively inhibits the Plasmodium falciparum 3D7 strain.Formula:C13H12N2OColor and Shape:SolidMolecular weight:212.25Mebendazole
CAS:Mebendazole is a benzimidazole anthelmintic with action on microtubule formation in parasitic worms and is used for treating intestinal worm infections like threadworms and roundworms.Formula:C16H13N3O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:295.29 g/molMiransertib
CAS:Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.Formula:C27H24N6Purity:98.83% - ≥95%Color and Shape:SolidMolecular weight:432.52Ref: TM-T3467
1mg52.00€5mg97.00€10mg169.00€25mg344.00€50mg567.00€100mg908.00€500mg1,795.00€1mL*10mM (DMSO)114.00€
