
Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Products of "Antiparasitics"
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(±)-Atovaquone Impurity C
CAS:Controlled ProductImpurity Atovaquone EP Impurity C, Atovaquone USP Related Compound A Applications (±)-Atovaquone Impuriyy C (Atorvastatin EP Impurity C), is the impurity of Atovaquone (A793500), which belongs to the class of naphthoquinones, that inhibits mitochondrial electron transport. It is an Antipneumocystic. References Hudson, A.T., et al.: Drugs Exp. Clin. Res., 17, 427 (1991), Fry, M., et al.: Biochem. Pharmacol., 43, 1545 (1992), El-Sadr, W.M., et al.: N. Engl. J. Med., 339, 1889 (1998),Formula:C22H17ClO3Color and Shape:Light YellowMolecular weight:364.82Dixanthogen
CAS:Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.Formula:C6H10O2S4Purity:95% - 98%Color and Shape:SolidMolecular weight:242.4Pentamidine dihydrochloride
CAS:Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (Formula:C19H26Cl2N4O2Purity:98.58%Color and Shape:SolidMolecular weight:413.34(E)-Cefodizime
CAS:Applications (E)-Cefodizime can be obtained from Ethyl Acetate (E899545) which is a chemical intermediate used in the production of various analgesics, antibiotics and antimalarial agents. References Mutti, F.G., et al.: Adv. Syn. Cata., 354, 3409 (2012); Subudhi, B., et al.: Bull. Chem. Soc., Ethiopia., 26, 455 (2012);Formula:C20H20N6O7S4Purity:>80%Color and Shape:NeatMolecular weight:584.6688Tinidazole
CAS:Formula:C8H13N3O4SPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:247.27Antileishmanial agent-24
Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM againstFormula:C34H29Cl4N3O2Purity:98%Color and Shape:SolidMolecular weight:653.427-Chloro-4-(2-methyl-1-pyrrolidinyl)-quinoline
CAS:Controlled ProductFormula:C14H15ClN2Color and Shape:NeatMolecular weight:246.74Conoidin A
CAS:Conoidin A is a cell permeable inhibitor of T.Formula:C10H8Br2N2O2Purity:98.00%Color and Shape:SolidMolecular weight:347.99INE963
CAS:INE963: Potent against Pf 3D7 (EC50=6nM), clears parasites in <24h; effective on P. falciparum/vivax isolates (EC50=0.01-7nM).Formula:C19H26N6O2SPurity:99.04%Color and Shape:SolidMolecular weight:402.51(2R,3R)-Benzhydryl 2,3-bis(benzyloxy)-4-hydroxybutanoate
Controlled ProductApplications (2R,3R)-Benzhydryl 2,3-bis(benzyloxy)-4-hydroxybutanoate is an intermediate in synthesizing 4-Phospho D-Erythronate (P355000), which is an intermediate in the synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Phosphorylated aldonic acids are strong inhibitors of 6-phosphogluconate dehydrogenase, and 4-phospho-D-erythronate (4PE) and 4-phospho-D-erythronohydroxamate are two of the strongest inhibitors of the Trypanosoma brucei enzyme. References Tanaka, N., et al.: J. Mol. Biol., 324, 519 (2002); Fitzpatrick, T., et al.: Biochem. J., 407, 1 (2007); Kalliri, E., et al.: J. Bacteriol., 190, 3793 (2008)Formula:C31H30O5Color and Shape:NeatMolecular weight:482.567Insecticidal agent 16
CAS:Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.Formula:C21H13Cl2F6N5O2SColor and Shape:SolidMolecular weight:584.32Ac-Atovaquone
CAS:Ac-Atovaquone, an ester-acetylated derivative of atovaquone, acts as a potent inhibitor of cytochrome bc1 (cytochrome bc1). This compound shows potential for use in malaria research.Formula:C24H21ClO4Color and Shape:SolidMolecular weight:408.87Bacopasaponin C
CAS:Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.Formula:C46H74O17Purity:97.85%Color and Shape:SolidMolecular weight:899.074-Amino-1-pentanol-d4 Benzyl Ether
Controlled ProductApplications 4-Amino-1-pentanol-d4 Benzyl Ether is an intermediate in the synthesis of Hydroxychloroquine-d4 Sulfate (H916902), which is an antimalarial; antirheumatic; lupus erythematosus suppressant. References Yarden, Y., et al.: Nature, 323, 226 (1986), Seifert, R., et al.: J. Biol. Chem., 264, 8771 (1989), Gahl, W., et al.: Mol. Genet. Metab., 76, 234 (2002), Card, J., et al.: Toxicol. Sci., 75, 169 (2003),Formula:C12D4H13NO2Color and Shape:NeatMolecular weight:211.293Piperaquine-d6 Tetraphosphate
CAS:Controlled ProductApplications Piperaquine-d6, is a 4-aminoquinoline derivative used as an antimalarial agent. Piperaquine interferes with physiological function of the food vacuole membrane of the trophozoites leading to autophagocytosis of the parasites. It is commonly used in combination with Dihydroartemisinin (D448360) for the treatment of multi-drug resistant falciparum malaria. References Nguyen, T.M.T. et al.: Tap Chi Duoc Hoc, 57, 22 (2007); Song, J. et al.: Malaria J., 10, 231 (2011);Formula:C29H26D6Cl2N6•4H3PO4Color and Shape:NeatMolecular weight:933.53Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Formula:C16H17BrClN3O3Purity:97.67%Color and Shape:Off-White SolidMolecular weight:414.685-(N-Ethyl-N-2-hydroxyethylamino)-2-penthlamine
CAS:Controlled ProductApplications 5-(N-Ethyl-N-2-hydroxyethylamino)-2-penthlamine is a useful synthetic intermediate in the synthesis of Hydroxy Chloroquine (H905300/H905305); a major metabolite of Chloroquine (C379965, diphosphate salt) which is a standard anti-malarial drug. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003); Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003); Huang, S., et al.: Talanta, 64, 887 (2004); Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983); Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998); Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999)Formula:C11H26N2OColor and Shape:NeatMolecular weight:202.337cis-Atovaquone-d5 (contains 10% trans isomer)
CAS:Controlled ProductApplications Cis isomer of Atovaquone-d5.Formula:C22H14D5ClO3Color and Shape:NeatMolecular weight:371.87trans-Clopenthixol dihydrochloride
CAS:Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].Formula:C22H27Cl3N2OSPurity:98%Color and Shape:SolidMolecular weight:473.89Atherosperminine
CAS:Atherosperminine inhibits AChE/BChE and relaxes trachealis via cAMP phosphodiesterase inhibition.Formula:C20H23NO2Purity:99.4%Color and Shape:SolidMolecular weight:309.4Piperonyl butoxide
CAS:Piperonyl butoxide (Pyrenone 606) is an insecticide synergist, particularly for rotenone and pyrethroids.Formula:C19H30O5Purity:99.84%Color and Shape:Pale Yellow Liquid Oil LiquidMolecular weight:338.44Antileishmanial agent-21
Antileishmanial agent-21 (compound 4e) functions as an inhibitor of Leishmania pteridine reductase 1 (Lm-PTR1), employing an anti-folate mechanism.Formula:C21H16N2O3Purity:98%Color and Shape:SolidMolecular weight:344.36UCB7362
CAS:UCB7362 (GLXC-26743) is an orally available and potent plasmepsin X (PMX) inhibitor with anti-malarial activity.UCB7362 inhibits parasite reproduction.Formula:C25H26ClN5O3Purity:97.38%Color and Shape:SolidMolecular weight:479.963-Aminopropionitrile (Stabilized with K2CO3)
CAS:Controlled ProductFormula:C3H6N2Color and Shape:NeatMolecular weight:70.09Eflornithine
CAS:Eflornithine blocks ornithine decarboxylase, treating African trypanosomiasis and female facial hair.Formula:C6H12F2N2O2Purity:99.44% - 99.84%Color and Shape:SolidMolecular weight:182.17Antileishmanial agent-20
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L.Formula:C15H16N4O3Purity:98%Color and Shape:SolidMolecular weight:300.31Miltefosine
CAS:Formula:C21H46NO4PPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:407.58Kojic acid
CAS:Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 μM for mushroom tyrosinase.Formula:C6H6O4Purity:99.34% - 99.72%Color and Shape:Prismatic Needles From Acetone Ethanol+Ether Or Methanol+Ethyl Acetate Tan PowderMolecular weight:142.11Primaquine
CAS:Primaquine is an antimalarial compound and a gametocytocide, clearing liver schizonts and dormant forms of Plasmodium vivax.Formula:C15H21N3OPurity:98.62%Color and Shape:SolidMolecular weight:259.35Antileishmanial agent-22
Antileishmanial agent-22 (compound 15b) serves as an antiparasitic and antibacterial, exhibiting activities against Leishmania (IC50 = 0.408 μM), malaria, andFormula:C29H26Cl2N4O3Purity:98%Color and Shape:SolidMolecular weight:549.45Osthole
CAS:Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.Formula:C15H16O3Purity:99.93% - 99.96%Color and Shape:Fine White PowderMolecular weight:244.29Brotianide
CAS:Brotianide (BAY-VA4059) has anthelmintic activity and is highly potent against liver fluke and gastric fluke infestations and can be used to treat acute,Formula:C15H10Br2ClNO2SPurity:98% - 98.44%Color and Shape:SolidMolecular weight:463.57(±)-Emodin bianthrone
CAS:(±)-Emodin bianthrone (compound 10), a naturally occurring substance, demonstrates antimalarial, antitubercular, and antifungal properties [1].Formula:C30H22O8Purity:98%Color and Shape:SolidMolecular weight:510.49Dapsone
CAS:Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.Formula:C12H12N2O2SPurity:99.84%Color and Shape:White To Creamy Solid CrystallineMolecular weight:248.3Quinfamide
CAS:Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis.Formula:C16H13Cl2NO4Purity:98.88%Color and Shape:SolidMolecular weight:354.18Ref: TM-T16705
1mg50.00€5mg105.00€10mg156.00€25mg255.00€50mg368.00€100mg505.00€200mg692.00€1mL*10mM (DMSO)111.00€SLU-10906
CAS:SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.Formula:C22H21BFN5O2Color and Shape:SolidMolecular weight:417.244Tafenoquine Succinate
CAS:Tafenoquine Succinate (WR 238605 (Succinate)) is an 8-aminoquinoline. and is an agent of anti-malarial prophylactic.Formula:C28H34F3N3O7Purity:99.84%Color and Shape:SolidMolecular weight:581.58Nicarbazin
CAS:Nicarbazin (Nicoxin) is an equimolar complex of 4, 4'-Dinitrocarbanilide and 2-Hydroxy-4, 6-dimethylpyrimidine. A coccidiostat for poultry.Formula:C19H18N6O6Purity:99.54%Color and Shape:Crystals Yellow Or Greenish Yellow Powder Odorless With A Bit Of SmellMolecular weight:426.38(9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol
CAS:Formula:C30H32Cl3NOPurity:98%Color and Shape:SolidMolecular weight:528.9402Piperaquine phosphate
CAS:Piperaquine phosphate is an antimalarial compound commonly used in combination with artemisinin to inhibit Plasmodium falciparum.Formula:C29H32Cl2N6xH3O4PPurity:99.17%Color and Shape:SolidMolecular weight:535.52(Free base)Azlocillin sodium salt
CAS:Azlocillin sodium, an acylampicillin, is a broad-spectrum antibioticsFormula:C20H22N5NaO6SPurity:97.63% - 97.63%Color and Shape:SolidMolecular weight:483.47Cletoquine
CAS:Cletoquine, Hydroxychloroquine's active metabolite, fights CHIKV, has antimalarial properties, and may treat autoimmune diseases.Formula:C16H22ClN3OPurity:97.26%Color and Shape:SolidMolecular weight:307.82Suramin Sodium Salt
CAS:Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.Formula:C51H34N6Na6O23S6Purity:97.47% - 99.97%Color and Shape:WhiteMolecular weight:1429.15Antimalarial agent 1
CAS:Antimalarial agent 1 is an effective antimalarial agent.Formula:C12H21N6O4PPurity:98.35% - 99.04%Color and Shape:SolidMolecular weight:344.31Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-
CAS:Formula:C20H24N2O2Purity:97%Color and Shape:SolidMolecular weight:324.416759999999958304-vs
8304-vs is a macrocyclic anti-Plasmodial compound that irreversibly binds to and inhibits the Plasmodium proteasome, effectively halting the growth ofFormula:C35H53N5O8SPurity:98%Color and Shape:SolidMolecular weight:703.89Dithiazanine iodide
CAS:Dithiazanine iodide (Netocyd) is a benzothiazole.Formula:C23H23IN2S2Purity:99% - 99.24%Color and Shape:SolidMolecular weight:518.48