Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Products of "Antiparasitics"
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Cletoquine-D4 Oxalate
CAS:Controlled ProductApplications A labelled metabolite of Hydroxychloroquine. References Polet, H., et al.: J. Cell. Physiol., 122, 415 (1985), Gabriel, H., et al.: Eur. J. Immunol., 23, 2704 (1993), Gordon, C., et al.: Br. J. Rheumatol., 35, 226 (1996), Means, T., et al.: J. Clin. Invest., 115, 407 (2005),Formula:C18H20D4ClN3O5Color and Shape:NeatMolecular weight:401.88Artemether
CAS:Formula:C16H26O5Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:298.38Fosravuconazole L-lysine ethanolate
CAS:Fosravuconazole L-lysine ethanolate, a prodrug for ravuconazole, treats onychomycosis in Japan.Formula:C31H40F2N7O8PSPurity:95%Color and Shape:SolidMolecular weight:739.7DSM1465
DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.Formula:C17H12ClF6N5O2Color and Shape:SolidMolecular weight:467.753Primaquine
CAS:Primaquine is an antimalarial agent with action on Plasmodium hypnozoites in the liver and is used for preventing relapses of malaria caused by Plasmodium vivax and Plasmodium ovale.Formula:C15H21N3OPurity:Min. 95%Color and Shape:PowderMolecular weight:259.35 g/molNilutamide
CAS:Nilutamide, a nonsteroidal anti-androgen, treats prostate cancer by blocking androgen receptors, not affecting other hormone receptors.Formula:C12H10F3N3O4Purity:98.45% - 98.67%Color and Shape:Crystalline SolidMolecular weight:317.22Symetine
CAS:Symetine(L 16726) is a small molecule compound with antiparasitic activity that can be used to study amoebic liver abscesses in guinea pigs.Formula:C30H48N2O2Purity:99.79%Color and Shape:SolidMolecular weight:468.71Paromomycin Sulfate
CAS:Formula:C23H45N5O14·xH2SO4Purity:>92.0%(HPLC)Color and Shape:White to Almost white powder to crystalNiclosamide Ethanolamine Salt
CAS:Formula:C13H8Cl2N2O4·C2H7NOPurity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:388.20Diazinon
CAS:Diazinon (Dimpylate) is a thiophosphoric acid ester, functioning as a nonsystemic organophosphate insecticide that effectively targets and controls a variety ofFormula:C12H21N2O3PSPurity:97.79% - 99.89%Color and Shape:Colorless Oil Ethanol/Xylene/Acetone With A Flash Point In The Range 82-105° FMolecular weight:304.35Menoctone
CAS:Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.Formula:C24H32O3Color and Shape:SolidMolecular weight:368.51(R)-Hydroxychloroquine
CAS:Controlled ProductApplications 2-[[(4R)-4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-ethanol is an antimalarial drug more commonly known as (R)-hydroxychloroquine. References The Canadian Hydroxychloroquine Study Group: N. Engl. J. Med., 324, 150 (1991).Formula:C18H26ClN3OColor and Shape:NeatMolecular weight:335.87Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Formula:C22H24ClNO4Purity:99.53%Color and Shape:SolidMolecular weight:401.88Ref: TM-T10990
1mg58.00€5mg111.00€10mg160.00€25mg264.00€50mg396.00€100mg563.00€1mL*10mM (DMSO)124.00€Tioxazafen
CAS:Tioxazafen is a disubstituted oxadiazole, and is a broad-spectrum seed treatment nematicide.Formula:C12H8N2OSPurity:99.66%Color and Shape:N9 5/90 0% R White SolidMolecular weight:228.27Ref: TM-T13928
5mg50.00€10mg74.00€25mg135.00€50mg197.00€100mg298.00€200mg420.00€1mL*10mM (DMSO)50.00€lufenuron
CAS:Lufenuron (Fluphenacur) is a chitin-synthesis inhibitor.Formula:C17H8Cl2F8N2O3Purity:99.87%Color and Shape:CoaMolecular weight:511.15Clofazimine
CAS:Formula:C27H22Cl2N4Purity:>98.0%(T)(HPLC)Color and Shape:Yellow to Amber to Dark red powder to crystalMolecular weight:473.40DihydroarteMisinic acid
CAS:DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinalFormula:C15H24O2Purity:99.06% - 99.17%Color and Shape:SolidMolecular weight:236.35GSK3186899
CAS:GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.Formula:C19H28F3N7O3SPurity:98.35% - 99.45%Color and Shape:SolidMolecular weight:491.53Antileishmanial agent-17
CAS:Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells.Formula:C27H37N5O5Purity:98%Color and Shape:SolidMolecular weight:511.61Hexyl gallate
CAS:Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.Formula:C13H18O5Purity:99.81%Color and Shape:SolidMolecular weight:254.28Benznidazol
CAS:Benznidazol (Benznidazole)e has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulatingFormula:C12H12N4O3Purity:100% - 99.53%Color and Shape:SolidMolecular weight:260.25Acetylspiramycin
CAS:Acetylspiramycin (Spiramycin B) targets 50S ribosome to inhibit protein synthesis.Formula:C45H76N2O15Purity:≥98%Color and Shape:White PowderMolecular weight:885.09Bruceine A
CAS:Bruceine A, a quassinoid from Brucea javanica fruit, may treat canine babesiosis.Formula:C26H34O11Purity:99.13% - 99.85%Color and Shape:SolidMolecular weight:522.54Ref: TM-T2S2046
1mg56.00€5mg119.00€10mg169.00€25mg283.00€50mg435.00€100mg640.00€1mL*10mM (DMSO)136.00€Nifuratel
CAS:Formula:C10H11N3O5SPurity:>98.0%(HPLC)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:285.27Clindamycin phosphate
CAS:Clindamycin phosphate: a broad-spectrum chlorinated antibiotic, modified from lincomycin, used topically.Formula:C18H34ClN2O8PSPurity:98.15%Color and Shape:White SolidMolecular weight:504.96Antiproliferative agent-56
Antiproliferative agent-56 (Compound 31) is an antimalarial agent that inhibits the Pf3D7 strain of the malaria parasite Plasmodium falciparum with an IC50 of >12.5 (48h) and 0.03 μM (98h), displaying slow-acting characteristics.Color and Shape:Odour SolidHYPOCRELLIN B
CAS:HYPOCRELLIN B, from Hypocrella bambusae, breaks DNA, triggers apoptosis in ovarian cells, and stops Staphylococcus growth via ROS.Formula:C30H24O9Purity:98% - 98.87%Color and Shape:SolidMolecular weight:528.51Spiramycin
CAS:Spiramycin, a Streptomyces-made macrolide antibiotic, targets gram-positive pathogens, N. gonorrhoeae, staph, and Toxoplasma gondii.Formula:C43H74N2O14Purity:90.59% - 97.92%Color and Shape:SolidMolecular weight:843.07Fmoc-N-Me-Phe-OH
CAS:Fmoc-N-Me-Phe-OH (Fmoc-N-methyl-L-phenylalanine) is a Malaria Parasite inhibitor.Formula:C25H23NO4Purity:≥95%Color and Shape:White PowderMolecular weight:401.45(3R-cis)-Dihydro-3-hydroxy-4-(phenylmethoxy)-2(3H)-furanone
CAS:Controlled ProductFormula:C11H12O4Color and Shape:NeatMolecular weight:208.215-O-Demethyl-28-Oxo-Avermectin A1A
CAS:Applications 5-O-Demethyl-28-oxo-Avermectin A1a is a derivatie of Ivermectin (I940800), which is a semi-synthetic derivative of Abamectin. An invitro inhibitor of SARS-CoV-2/ Covid-19. References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178Formula:C48H70O15Color and Shape:NeatMolecular weight:887.06Anti-inflammatory agent 40
Anti-inflammatory agent 40 is a promising, orally-active compound with anti-malarial and anti-inflammatory properties.Formula:C30H24Cl2N2O4Purity:98%Color and Shape:SolidMolecular weight:547.43Pentamidine Isethionate
CAS:Formula:C19H24N4O2·2C2H6O4SPurity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:592.68Epimagnolin A
CAS:Epimagnolin A is a lignan obtained from the flower buds of Magnolia fargesii, which is traditionally used in Asian medicine for treating headache and nasalFormula:C23H28O7Purity:99.82% - ≥98%Color and Shape:SolidMolecular weight:416.46Ref: TM-TN1610
1mg111.00€2mg166.00€5mg283.00€10mg419.00€25mg682.00€50mg939.00€100mg1,264.00€1mL*10mM (DMSO)320.00€N-Desethyl amodiaquine
CAS:N-Desethyl amodiaquine is an antiparasitic agent and the major bioactive amodiaquine metabolite.Formula:C18H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:327.81Alkaline tryptase-IN-1
Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.Formula:C29H33BrN2O2SColor and Shape:SolidMolecular weight:553.55Imidocarb Dipropionate
CAS:Formula:C19H20N6O·2C3H6O2Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:496.57Diethylcarbamazine Citrate
CAS:Formula:C10H21N3O·C6H8O7Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:391.42Paromomycin sulfate salt
CAS:Formula:C23H47N5O18SPurity:%Color and Shape:SolidMolecular weight:713.707Deschloro Atovaquone
CAS:Controlled ProductApplications Naphthoquinone antimalarials. Atovaquone derivative.Formula:C22H20O3Color and Shape:NeatMolecular weight:332.39Niclosamide
CAS:Niclosamide (Niclocide)(BAY2353) is used to treat most tapeworm infections by inhibiting DNA replication.Formula:C13H8Cl2N2O4Purity:96.83% - 98.9%Color and Shape:Pale Yellow Crystals SolidMolecular weight:327.12Artemether
CAS:Artemether (CGP 56696) is an antimalarial agent used to treat acute uncomplicated malaria.Formula:C16H26O5Purity:99.87% - 99.93%Color and Shape:SolidMolecular weight:298.37LUPENONE
CAS:Lupenone is a natural product isolated from Rhizoma Musae and has good anti-diabetic activity,and has anti-inflammatory activity.lupenone were potent PTP1BFormula:C30H48OPurity:98% - 99.92%Color and Shape:SolidMolecular weight:424.7Lumefantrine
CAS:Lumefantrine is an antimalarial compound with action on erythrocytic stages of Plasmodium falciparum by inhibiting β-hematin formation and is used for treating malaria in combination with artemether.Formula:C30H32Cl3NOPurity:Min. 95%Color and Shape:PowderMolecular weight:528.94 g/molAmprolium
CAS:Amprolium is a veterinary coccidiostat that interferes with THIAMINE metabolism.Formula:C14H19N4·ClPurity:98%Color and Shape:SolidMolecular weight:278.79PK 11195
CAS:PK 11195 binds translocator protein; anti-Leishmania with IC50s: L. amazonensis 14.2 μM, L. major 8.2 μM, L. braziliensis 3.5 μM.Formula:C21H21ClN2OPurity:99.05%Color and Shape:SolidMolecular weight:352.86ML251
CAS:ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Formula:C17H13Cl2N3O4SPurity:99.87%Color and Shape:SolidMolecular weight:426.27Ref: TM-T64320
1mg133.00€5mg274.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€500mg2,717.00€1mL*10mM (DMSO)301.00€AWZ1066S
CAS:AWZ1066S is a highly specific anti-Wolbachia drug candidate for the short-course treatment of filariasis (EC50: 2.5 nM in cell assay).Formula:C19H19F3N6OPurity:98.32%Color and Shape:SolidMolecular weight:404.39Ref: TM-T10423
1mg44.00€5mg93.00€10mg153.00€25mg235.00€50mg344.00€100mg512.00€200mg728.00€1mL*10mM (DMSO)93.00€
