Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Products of "Antiparasitics"
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Artemisinin
CAS:Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.Formula:C15H22O5Purity:100% - 99.87%Color and Shape:Crystalline SolidMolecular weight:282.33Ivermectin
CAS:Formula:C48H74O14Purity:>93.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:875.11Carboxymefloquine-d3
CAS:Controlled ProductApplications Labelled Carboxymefloquine (C178700). Carboxymefloquine is a metabolite of Mefloquine (M207050). References Crevoisier, C., et al.: Eur. J. Clin. Pharmacol., 53, 135 (1997), Ridtitid, W., et al.: J. Pharm. Pharmacol., 52, 1265 (2000),Formula:C12H2D3F6NO2Color and Shape:NeatMolecular weight:312.18Chloroquine phosphate
CAS:Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is used as an autophagy inhibitor. Chloroquine also is an inhibitor of TLRs.Formula:C18H26CLN3·2(H3PO4)Purity:99.64% - ≥95%Color and Shape:White To Slightly Yellow Crystalline Powder White SolidMolecular weight:515.872-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
CAS:Formula:C27H22Cl2N4Purity:98%Color and Shape:SolidMolecular weight:473.3964Ivermectin
CAS:Naturally produced by the soil bacterium Streptomyces avermitili, it is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, Ivermectin indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.Formula:C48H74O14Purity:85%MinMolecular weight:875.1 g/molColumbin
CAS:Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.Formula:C20H22O6Purity:99.34% - 99.74%Color and Shape:SolidMolecular weight:358.39Antileishmanial agent-15
CAS:Antileishmanial agent-15 (compound 13c) exhibits potent activity against L.Formula:C28H39N5O4Purity:98%Color and Shape:SolidMolecular weight:509.64Allopurinol riboside
CAS:Allopurinol riboside, an allopurinol metabolite, inhibits purine nucleoside phosphorylase in parasites with a Ki of 277 μM.Formula:C10H12N4O5Purity:100% - 99.21%Color and Shape:SolidMolecular weight:268.23Closantel
CAS:Closantel (R-31520), a salicylanilide anthelmintic compound, shows different anthelmintic spectra and obvious toxicity in mammals.Formula:C22H14Cl2I2N2O2Purity:98.52% - 99.76%Color and Shape:White To Yellowish PowderMolecular weight:663.07Methylclonazepam
CAS:Methylclonazepam is a benzodiazepine with anxiolytic properties. It inhibits the uptake of 5-hydroxytryptamine by Schistosoma mansoni, and its derivatives exhibit anti-Schistosoma mansoni activity.Formula:C16H12ClN3O3Color and Shape:SolidMolecular weight:329.74Closantel Sodium
CAS:Closantel is a salicylanilide anthelmintic compound; exhibits different anthelmintic spectra and apparent toxicity in mammals.Formula:C22H13Cl2I2N2O2·NaPurity:99.48%Color and Shape:PowderMolecular weight:685.06Benzyl benzoate
CAS:Benzyl benzoate treats scabies and lice; not first choice due to irritation.Formula:C14H12O2Purity:99.36% - 99.75%Color and Shape:Colourless To Pale Yellow Solid CrystallineMolecular weight:212.24Methylene Blue
CAS:Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And methylene Blue inhibits soluble guanylyl cyclase.Formula:C16H18ClN3SPurity:96.82%Color and Shape:Dark Green Crystals Or Powder From Chloroform-Ethyl Ether Green Fine Crystalline PowderMolecular weight:319.85Ref: IN-DA00ILH6
1g36.00€5g77.00€10g117.00€15g166.00€25g187.00€50g352.00€75g693.00€100gTo inquire100mg29.00€250mg26.00€Lumefantrine
CAS:Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.Formula:C30H32Cl3NOPurity:98.36%Color and Shape:Yellow SolidMolecular weight:528.94S-WJM992
S-WJM992 (compound 10ahb) serves as an antiparasitic agent, effectively inhibiting ATPase activity in high [Na+] environments. It also significantly counteracts parasites resistant to PfATP4 inhibitors. Additionally, S-WJM992 acts as a potential transmission blocker by impeding gamete development and halting the transmission of parasites to mosquitoes during blood feeding.Formula:C22H18ClFN6O3Color and Shape:SolidMolecular weight:468.872-Hydroxy Levamisole
CAS:Controlled ProductApplications Levamisole derivative.Formula:C11H12N2OSColor and Shape:NeatMolecular weight:220.29N-Desethyl amodiaquine dihydrochloride
CAS:N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite.Formula:C18H20Cl3N3OPurity:98.83%Color and Shape:SolidMolecular weight:400.73Ref: TM-T12154L
1mg113.00€5mg235.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€500mg2,717.00€1mL*10mM (DMSO)259.00€BQR-695
CAS:BQR-695 (NVP-BQR695) is a PI4K inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively.Formula:C19H20N4O3Purity:98.91% - 99.69%Color and Shape:SolidMolecular weight:352.393-Chloro-2-methylaniline
CAS:Formula:C7H8ClNColor and Shape:Light Yellow To Light BrownMolecular weight:141.60Fenchlorphos
CAS:Fenchlorphos (Dermafos) is a cholinesterase inhibitor, used as an insecticide.Formula:C8H8Cl3O3PSPurity:100% - 98.1%Color and Shape:Colorless CrystalsMolecular weight:321.55Oxfendazole
CAS:Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.Formula:C15H13N3O3SPurity:98.81% - 98.99%Color and Shape:White To Yellowish PowderMolecular weight:315.35Broxaldine
CAS:Broxaldine (Brobenzoxaldine) is a small molecular drug with antiprotozoal activity.Formula:C17H11Br2NO2Purity:100%Color and Shape:SolidMolecular weight:421.08Emodepside
CAS:Emodepside (Bay 44-4400) is an anthelmintic drug that is effective against a number of gastrointestinal nematodes,with broad-spectrum anthelmintic activity.Formula:C60H90N6O14Purity:98.89%Color and Shape:SolidMolecular weight:1119.39Ref: TM-T7901
1mg57.00€2mg82.00€5mg115.00€10mg170.00€25mg313.00€50mg542.00€100mg778.00€1mL*10mM (DMSO)208.00€Anti-Trypanosoma cruzi agent-6
Anti-Trypanosoma cruzi agent-6 (Compound 8) exhibits inhibitory activity against Trypanosoma cruzi. It effectively suppresses the epimastigote, trypomastigote, and amastigote forms of T. cruzi, with IC50 values of 24.7 µM, 1.8 µM, and 1.6 µM, respectively.Formula:C19H20N2O5Color and Shape:SolidMolecular weight:356.37Quinidine sulfate dihydrate
CAS:Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitorFormula:C40H54N4O10SPurity:99.85%Color and Shape:White To Light Yellow Crystal PowdeMolecular weight:782.9Ref: TM-T8125
5mg44.00€10mg55.00€25mg78.00€50mg99.00€100mg150.00€200mg219.00€500mg366.00€1mL*10mM (DMSO)65.00€Quinine
CAS:Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria.Formula:C20H24N2O2Purity:99.93% - 99.97%Color and Shape:White Solid PowderMolecular weight:324.42Antimalarial agent 19
CAS:Compound 6e, an antimalarial, targets P. falciparum K1 (EC50 0.3 µM) and P. berghei (EC50 15.3 µM); has high solubility and stability.Formula:C22H33Cl2N5SPurity:98%Color and Shape:SolidMolecular weight:470.5GNF179
CAS:GNF179 is an optimized 8,8-dimethyl IP analog.Formula:C22H23ClFN5OPurity:98.9%Color and Shape:SolidMolecular weight:427.9Ref: TM-T15409
1mg133.00€5mg274.00€10mg454.00€25mg750.00€50mg1,026.00€100mg1,406.00€1mL*10mM (DMSO)303.00€MMV390048
CAS:MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM).Formula:C18H14F3N3O2SPurity:97.48%Color and Shape:SolidMolecular weight:393.38Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Formula:C14H10F3NO2Purity:98.68%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:281.23GUANABENZ
CAS:GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist.Formula:C8H8Cl2N4Purity:98.31%Color and Shape:White Solid From Acetonitrile SolidMolecular weight:231.08Ref: TM-T5471
2mg35.00€5mg48.00€10mg65.00€25mg104.00€50mg148.00€100mg215.00€200mg319.00€1mL*10mM (DMSO)50.00€Artesunate
CAS:Formula:C19H28O8Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:384.435-Amino-1-(1,1-dimethylethyl)-3-[(3-methylphenyl)methyl]-1H-pyrazole-4-carbonitrile
Controlled ProductApplications 5-Amino-1-(1,1-dimethylethyl)-3-[(3-methylphenyl)methyl]-1H-pyrazole-4-carbonitrile is an derivative in the synthesis of small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by toxoplasma gondii. References Lourido, S., et al.: J. Med. Chem., 56, 3068 (2013);Formula:C17H22N4Color and Shape:NeatMolecular weight:282.383Anticancer agent 140
Compound 140 (Compd 3) exhibits potential anticancer and antiparasitic activities [1].Formula:C20H26N2OPurity:98%Color and Shape:SolidMolecular weight:310.43(6R,13S,25R)-5-O-Demethyl-28-deoxy-5-O-[(1,1-dimethylethyl)dimethylsilyl]-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl] Milbemycin B
CAS:Controlled ProductApplications (6R,13S,25R)-5-O-Demethyl-28-deoxy-5-O-[(1,1-dimethylethyl)dimethylsilyl]-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl] Milbemycin B is an intermediate used in the synthesis of Milbemycin D (M344290), which is a macrocyclic lactones that can be used as a nematocide and insecticide. References Arena, J. P., et al.: J. Parasitol 81, 286 (1995); Takiguchi, Y., et al.: J. Antibiot 36, 502 (1983)Formula:C40H64O8SiColor and Shape:NeatMolecular weight:701.02Niclosamide olamine
CAS:Niclosamide olamine (Niclosamide Ethanolamine salt) is an Repellent, Insect Attractant and Chemosterilant.Formula:C15H15Cl2N3O5Purity:99.89%Color and Shape:Bright Yellow Crystalline Physical Description Yellow Solid Insoluble In Water (Ntp 1992)Molecular weight:388.2Bephenium (hydroxynaphthoate)
CAS:Bephenium hydroxynaphthoate is a B-type AChR activator, formerly used in the treatment of hookworm infections and ascariasis.Formula:C28H29NO4Purity:99.87%Color and Shape:SolidMolecular weight:443.53Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Chloroquine-d4 Phosphate Salt
CAS:Controlled ProductApplications Labelled anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. It is a COVID19-related research product. References Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983), Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998), Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999),Formula:C18H22D4ClN3•xH3PO4Color and Shape:Yellow SolidMolecular weight:323.9098AZ960
CAS:AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formula:C18H16F2N6Purity:96.02% - 98.51%Color and Shape:SolidMolecular weight:354.36Dichlorophen
CAS:Dichlorophen (DDM) is a nontoxic laxative vermicide of chlorinated phenol compound.Formula:C13H10Cl2O2Purity:99.11%Color and Shape:Colorless Crystals Slight Phenolic Odor And A Saline Phenolic Taste Moderately Toxic Used As A Fungicide AndMolecular weight:269.12Antimalarial agent 27
Antimalarial agent 27 (compound 11a) potently inhibits P.Formula:C10H11NNaO5PPurity:98%Color and Shape:SolidMolecular weight:279.16Antiparasitic agent-18
CAS:Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T.Formula:C25H21N7OPurity:98%Color and Shape:SolidMolecular weight:435.48Flubendazole
CAS:Formula:C16H12FN3O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:313.29Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formula:C47H76O16Purity:99.54% - 99.92%Color and Shape:SolidMolecular weight:897.1Ref: TM-T2P2806
1mg48.00€5mg120.00€10mg170.00€25mg283.00€50mg430.00€100mg620.00€1mL*10mM (DMSO)170.00€2-Acetamido-5-nitrothiazole
CAS:Formula:C5H5N3O3SPurity:>98.0%(T)(HPLC)Color and Shape:White to Amber powder to crystalMolecular weight:187.17N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
CAS:Controlled ProductApplications N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine is a metabolite of Chloroquine (C379965), a standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. References Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983), Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998), Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999),Formula:C18H26ClN3Color and Shape:Dark Orange To Dark BrownMolecular weight:319.87
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