Glycerolipids

Applications Glycerine Trioleate is one of the two components of Lorenzo's oil which is used in the investigational treatment of asymptomatic patients with adrenoleukodystrophy (ALD). References Sassa, T., et al.: J. Lipid Res,. 55, 524 (2014); Macro, C., et al.: J. Inherit. Metab. Dis., 35, 899 (2012); Alexander, S., et al.: Expert Rev. Neurother., 8, 1367 (2008)

Stability Hygroscopic Applications Labelled glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states. References Perides, G., et al.: J. Biol. Chem., 262, 13742 (1987),

Applications 1,3-Distearoyl-2-oleoyl Glycerol is a triacid triglyceride found in cocoa butter and is used in the improvement of chocolate. References Padley, F.B. et al.: Rev. Int. Choc., 27, 278 (1972);

It can be used for the preparation of solid lipid nanoparticles (SLN) composed of trimyristin (solid lipid) and poloxamer 407 (surfactant). It is also used as a synthesis reagent and as an emollient, refatting agent, skin conditioning agent, solvents and viscosity controlling agents. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Glycerol tributyrate is a triglyceride that may inhibit cell growth and induce cell differentiation. It is used to to induce differentiation of malignant cells followed by arrest of cell growth and apoptosis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications Used in a novel process for preparing β-hydroxy-fatty acids which are useful as base material for lipids A, LB films, cosmetics, liquid crystals etc. References Hanahan, D., et al.: J. Mol. Biol., 166, 557 (1983), Yang, S., et al.: Biotechnol. Bioeng., 43, 1124 (1994), Ramsay, J., et al.: Can. J. Microbiol., 41, 262 (1995), Rehm, B., et al.: Intl. J. Biol. Macromol., 25, 3 (1999),

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Stability Light Sensitive Applications 1,2-Dioleoyl-rac-glycerol is an analog of 1,3-Dioleoylglycerol (D484210) which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents. References Accardo, A., et. al.: J. Mater. Chem. B., 1, 617 (2013)

Applications Ceramide-1-phosphate blocks apoptosis through inhibition of acid sphingomyelinase in macrophages. References Furukawa, A., et al.: Mol. Cell. Biochem., 305, 27 (2007), Chen-Quay, S., et al.: J. Pharm. Sci., 98, 606 (2009),