Sterols

Bufalin is a bufadienolide compound, which is a type of steroid derived primarily from toad venom, specifically from the skin and parotid venom glands of the toad species Bufo gargarizans. Its mode of action involves the inhibition of Na+/K+-ATPase, an enzyme critical for maintaining the electrochemical gradient across cell membranes. By disrupting this gradient, Bufalin affects cellular ion homeostasis and induces apoptosis in various cancer cell lines. Bufalin is primarily studied for its potential therapeutic applications in oncology. It has shown promise in preclinical models for inhibiting tumor growth and inducing apoptosis in several types of cancer, including leukemia, prostate cancer, and hepatocellular carcinoma. Additionally, due to its effects on ionic gradients, Bufalin exhibits cardiotonic properties, though care must be taken given its narrow therapeutic index and potential for toxicity. Continued research is aimed at elucidating precise mechanisms, optimizing formulations, and assessing safety profiles to harness Bufalin’s pharmacological potential effectively.

Please enquire for more information about Ganoderenic acid B including the price, delivery time and more detailed product information at the technical inquiry form on this page

24-epi-Castasterone is a brassinosteroid, which is a class of plant steroids, often extracted from various plant tissues synthesized in small quantities. This compound is primarily derived from plant sources such as seeds, pollen, and young vegetative tissues. It functions by binding to specific receptor kinases on plant cell membranes, thereby initiating a cascade of intracellular signaling that regulates gene expression. These pathways are crucial for the modulation of plant growth and development processes. Its applications are extensive within the realm of plant physiology research, where it is utilized to study the regulation of growth, differentiation, and adaptation mechanisms in plants. Additionally, 24-epi-castasterone plays a pivotal role in research focused on enhancing stress tolerance, investigating hormonal interactions, and improving overall plant health and yield. Understanding its specific modes of action and effects contributes significantly to advancements in agricultural biotechnology and plant biology fields.

Dihydroformononetin is an isoflavonoid phytoestrogen, which is a type of naturally occurring compound found primarily in leguminous plants. It is derived from plant sources such as red clover and soybeans, known for their rich isoflavone content. This compound undergoes metabolic conversion in plants and potentially in the human body, exerting effects through interactions with estrogen receptors. The mode of action of dihydroformononetin involves binding to estrogen receptors, mimicking estrogenic activity, and potentially influencing pathways related to hormonal balance and cellular processes. It can modulate different cellular pathways and exhibit antioxidant properties, adding to its pharmacological profile. Dihydroformononetin is studied for its applications in health and medicine. Its estrogenic activity makes it a candidate for research in hormone-related conditions such as menopause, osteoporosis, and cardiovascular health. Furthermore, its antioxidant capacity and ability to affect cellular pathways provide additional avenues for exploring anti-inflammatory and anticancer properties. Researchers are particularly interested in its role in modulating signaling pathways, which may have therapeutic implications for various diseases. However, more studies are necessary to fully understand its efficacy and safety profile.

Gracillin is a steroidal saponin, which is a bioactive compound derived from the plant genus Dioscorea. This natural product is characterized by its complex glycoside structure, where a sugar moiety is attached to a steroid-like aglycone. The mode of action of Gracillin involves its interaction with cellular membranes, leading to increased cell membrane permeability. This action is thought to disrupt normal cellular functions, making it a compound of interest for studying membrane dynamics. The applications of Gracillin are diverse, particularly within the field of pharmacology, where its potential therapeutic effects are being explored. Researchers are investigating its anticancer properties as it appears to induce apoptosis in certain cancer cell lines. Additionally, its role as a natural product with antimicrobial and antifungal activities is being studied, providing insights into the development of new therapeutic agents. Gracillin's ability to modulate biological membranes also extends its potential applications to fields such as drug delivery systems, where it may enhance the permeability and efficacy of pharmacological formulations.

Ophiopogonin B is a steroidal saponin compound, which is primarily derived from the root tubers of the plant Ophiopogon japonicus. This plant source, commonly used in traditional Chinese medicine, contributes to the compound's extraction. Ophiopogonin B exhibits a multifaceted mode of action, primarily recognized for its biological activities, including antioxidant, anti-inflammatory, and cardioprotective effects. The uses and applications of Ophiopogonin B are extensive within the biomedical research field. It has been investigated for its potential therapeutic effects in cardiovascular diseases, where it demonstrates protective capabilities against myocardial injury. Additionally, its role in modulating oxidative stress and inflammation provides a promising avenue for its application in chronic inflammatory conditions. Ongoing research is exploring its mechanisms further, potentially leading to novel insights into its pharmacological properties and expanding its applicability in health sciences.