Terpenoids

Acyclic terpene alcohol

Lactone

Cucurbitacin E is a triterpenoid compound, which is a natural product derived from plants in the Cucurbitaceae family. This bioactive compound exerts its effects primarily through the disruption of cytoskeletal integrity, inhibition of the JAK/STAT signaling pathway, and induction of apoptosis. These molecular activities make it a potent agent in research focusing on cellular proliferation and inflammation. In scientific studies, Cucurbitacin E has been extensively utilized due to its promising anticancer and anti-inflammatory properties. It has shown efficacy in inhibiting cancer cell growth and metastasis across various types, including breast, lung, and colon cancers. Additionally, its anti-inflammatory effects are leveraged in studies of inflammatory responses and disorders. Given its ability to interfere with key cellular pathways, it is a significant compound in the development of therapeutic strategies against cancer and inflammatory diseases. Researchers continue to explore its pharmacokinetics, bioavailability, and potential synergistic effects when used in combination therapies.

Lactone

Dihydroartemisinin is an antimalarial agent, which is a semi-synthetic derivative of artemisinin. Artemisinin is a naturally occurring sesquiterpene lactone derived from the sweet wormwood plant, Artemisia annua. The mode of action of dihydroartemisinin involves the generation of free radicals within the parasite's cells. This process occurs when the endoperoxide bridge in its chemical structure reacts with iron, leading to oxidative damage and subsequent parasite death. Dihydroartemisinin is primarily used in combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria. It is valued for its rapid onset of action and high efficacy against multidrug-resistant strains of P. falciparum. These qualities make it a critical component in artemisinin-based combination therapies (ACTs), which are the recommended first-line treatment for malaria in many parts of the world. The use of dihydroartemisinin, particularly in combination with partner drugs, helps prevent resistance development and enhances therapeutic outcomes.

3-O-Acetyl-alpha-boswellic acid analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Carboxylic acid with alcohol function

Ginsenoside Rf is a steroidal saponin, which is a bioactive compound found primarily in the roots of Panax ginseng, a plant widely used in traditional medicine. As a part of the ginsenoside family, this compound exerts its effects through modulation of several cellular pathways, including anti-inflammatory and antioxidant mechanisms. It is known to interact with glucocorticoid receptors and influence calcium ion channels, contributing to its potential neuroprotective and immunomodulatory effects. In scientific research, Ginsenoside Rf is investigated for its potential applications in pharmacology, particularly regarding its role in enhancing cognitive functions and its neuroprotective properties in neurological disorders. Additionally, it is studied for its potential anti-cancer properties due to its ability to induce apoptosis and inhibit cell proliferation in certain cancer cell lines. Scientists are exploring its efficacy and safety profiles to better understand its therapeutic potential and to develop novel applications in clinical settings.

Hydroxyvalerenic acid is a bioactive compound, which is primarily found in the roots of the Valeriana officinalis plant. This source is widely recognized in traditional medicine for its calming properties. The compound acts on the central nervous system, potentially modulating GABAergic activity, which may contribute to its sedative and anxiolytic effects. In scientific research, Hydroxyvalerenic acid is explored for its potential to support neurological function, and its application spans areas such as anxiety reduction and sleep disorder management. The complexity of its interaction with neurotransmitter systems presents opportunities for in-depth studies aimed at elucidating its biochemical pathways and therapeutic potential. Further investigations are warranted to understand its efficacy and safety profile, making it a subject of interest in neuropharmacological research.

Natural glycoside

Aromatic hydrocarbon

Natural glycoside

Linalool - Natural grade is a terpene alcohol, which is a naturally occurring compound found in over 200 plant species, including lavender, mint, and cinnamon. This compound is extracted from essential oils of these plants through steam distillation or solvent extraction, ensuring the retention of its natural properties. Linalool functions by interacting with olfactory receptors and the central nervous system, making it an effective agent in influencing mood and emotion. Its mechanisms are believed to be linked to the modulation of neurotransmitter activity, offering a calming effect. This compound is widely used in perfumery and flavor industries due to its pleasant floral aroma. In addition to its role in cosmetics and personal care products, such as lotions and soaps, linalool is utilized in food flavorings to impart a fresh, floral note. It is also explored in aromatherapy for its potential stress-relieving properties. As a subject of scientific research, linalool’s effects on mood, anxiety, and inflammation remain areas of active investigation, underscoring its significance in both applied and theoretical domains.

Lnuchinenolide B is a bioactive compound, which is a type of natural product often isolated from various plant species. This compound has garnered interest due to its origins in diverse botanical sources. Its mode of action is typically associated with its interaction at the molecular level with specific biological targets, potentially inhibiting or modulating particular enzymatic activities or receptor pathways. Such interaction underscores its capacity to influence biological processes, making it a compound of interest in pharmacological research. The uses and applications of lnuchinenolide B are primarily focused on its potential therapeutic effects. Researchers are investigating its role in modulating pathways relevant to inflammation, cancer, and other diseases. Studies have highlighted its promise in contributing to the development of novel therapeutic agents, given its unique structural and functional properties. Continued exploration of lnuchinenolide B holds promise for uncovering new insights into disease mechanisms and treatment strategies, thus underscoring its significance in scientific research.

Stability Light Sensitive Applications Carvone is useful for the treatment of various metabolic disorders and GI related disorders. References Shabi, M. M., et al.: Res. J. Pharm. Biol. Chem. Sci., 8, 328 (2017)

(1S)-(-)-(-)-Verbenone is a bicyclic monoterpene, which is a type of terpenoid compound. It is naturally sourced from various plants, predominantly from the essential oils of pines and other coniferous trees. The mode of action of Verbenone is intriguing; it acts as an anti-aggregation pheromone in certain beetle species, disrupting their communication and reducing infestation levels. This mechanism is particularly effective against bark beetles, which are known to cause significant damage to forestry ecosystems. The uses and applications of (1S)-(-)-(-)-Verbenone extend beyond pest management. In addition to its role as a semiochemical for altering insect behavior, it is also employed in the fragrance industry due to its pleasant, camphoraceous odor. This makes it a valuable component in the formulation of perfumes and other scented products. As such, (1S)-(-)-(-)-Verbenone serves as a versatile compound in both ecological control and aromatic applications, reflecting its dual functionality and importance in integrated pest management and industrial fragrance production.

Beta-Aescin (also known as€ beta-escin) is a saponin produced by the horse chestnut tree, Aesculus hippocastanum, with most published reports relating to the pharmacological properties that it shows. It is reported that beta-aescin is a safe and very tolerable drug in the treatment of post thrombotic syndrome and chronic venous insufficiency. Aescin shows promise in the treatment of arthritis and appears to have potential as an anti-cancer drug. In fact, beta-aescin is active on glioblastoma-initiating cells (GIC), which have the ability to initiate glioblastoma growth. Glioblastoma multiform is the most abundant primary tumor of the human nervous system. Beta-aescin was more efficient in diminishing GIC growth compared to present clinically used drugs.

Lucidenic acid P is a triterpenoid compound, which is a bioactive metabolite isolated from Ganoderma lucidum, a medicinal mushroom known for its diverse pharmacological properties. It is primarily sourced from the fruiting bodies of this fungus, where it is present as part of a complex mixture of triterpenoids. The mode of action of Lucidenic acid P involves modulation of various biochemical pathways, including antioxidative, anti-inflammatory, and immune-regulatory mechanisms. This compound exerts its effects through modulation of cellular signaling pathways, contributing to its potential therapeutic properties. Uses and applications of Lucidenic acid P are currently under extensive scientific investigation. It is being explored for its role in cancer therapy due to its potential to inhibit tumor growth and metastasis, as well as for its protective effects against oxidative stress-related diseases. Furthermore, studies suggest that it may have neuroprotective benefits, making it a promising candidate for research focused on neurodegenerative disorders.

Lanatoside B is a cardiac glycoside, which is a type of compound obtained from the leaves of the Digitalis lanata plant, commonly known as woolly foxglove. This compound belongs to a class of organic substances known for their potent effects on the heart's contractile capability. The primary mode of action of Lanatoside B involves inhibiting the sodium-potassium ATPase enzyme in cardiac tissues. This inhibition leads to an increase in intracellular sodium concentration, which subsequently boosts calcium ions available for myocardial contraction via the sodium-calcium exchange mechanism. Lanatoside B is primarily employed in the medical field for its cardiotonic properties. It is utilized to treat specific heart conditions such as atrial fibrillation and heart failure, where its ability to enhance cardiac output and regulate heart rhythm is particularly beneficial. Given its potent effects, the usage of Lanatoside B must be carefully controlled under clinical supervision to mitigate potential toxicity. It remains a subject of ongoing research, particularly in exploring its broader therapeutic potential and mechanisms of action.

Please enquire for more information about Daucol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Geosmin is an "earth" smelling aromatic compound that is produced by soil bacteria. Together with other substances, geosmin is a key constituent of petrichor, the pleasant scent released into the air following rainfall, after impact of water droplets with soil.

Ginsenoside Rh3 is a bioactive saponin compound, which is a principle component isolated from Panax ginseng, a perennial plant widely known for its medicinal properties. This compound represents a specific form of ginsenoside with distinct pharmacological characteristics derived through the deglycosylation process of other ginsenosides during processing or digestion. Ginsenoside Rh3 acts primarily through modulating cellular signaling pathways, influencing cell proliferation, apoptosis, and inflammation. It has been shown to interact with various molecular targets, such as inhibiting NF-κB activity and modulating MAPK pathways, which leads to its multifaceted biological effects. The applications of Ginsenoside Rh3 are diverse and significant in the biomedical and pharmaceutical fields. It is under investigation for its potential anti-cancer properties due to its ability to inhibit tumor growth and metastasis. Additionally, its anti-inflammatory and neuroprotective activities make it a candidate for studies in treating inflammatory diseases and neurodegenerative disorders. Given its broad range of biological activities, Ginsenoside Rh3 remains a focal point of research aiming to develop novel therapeutic strategies.

Tripdiolide is a bioactive diterpenoid, which is derived from the Chinese medicinal plant Tripterygium wilfordii, commonly known as Thunder God Vine. This compound exerts its effects through a complex mode of action, primarily involving the inhibition of nuclear factor kappa B (NF-kB) signaling pathways and the induction of apoptosis. Recent studies have also suggested its role in modulating the immune response by targeting specific cytokines and signaling pathways. The applications of Tripdiolide are primarily focused on its immunosuppressive and antitumor properties. In preclinical studies, it has shown potential in the treatment of autoimmune diseases and certain cancers. Its ability to downregulate pro-inflammatory cytokines makes it a candidate for therapeutic intervention in conditions such as rheumatoid arthritis and systemic lupus erythematosus. Additionally, due to its role in promoting apoptosis and inhibiting cell proliferation, Tripdiolide is being investigated within the oncology field to target malignant cell lines. Ongoing research aims to delineate its full therapeutic potential and optimize its efficacy and safety profile.

Alicyclic monobasic carboxylic acid

Cyclic alcohol

Hispidol is a naturally occurring flavonoid compound, which is extracted from the Leguminosae family of plants. This class of compounds is characterized by its polyphenolic structure, contributing to its role within plant defense mechanisms. With an origin primarily in legumes, hispidol’s bioactive properties stem from its ability to interact with various enzymatic and receptor pathways. Through its mode of action, hispidol exhibits inhibitory effects on several cellular enzymes and signaling pathways. This includes modulation of oxidative stress markers and interference with inflammatory cascades by inhibiting the expression of key transcription factors involved in inflammation. The applications of hispidol are widely researched within the field of pharmacology. Its potential includes use as an anti-inflammatory agent and its roles in counteracting oxidative stress-related damage. The compound's efficacy in possibly regulating metabolic conditions such as diabetes, and its cytotoxic properties against certain cancer cell lines, provide vast avenues for scientific investigation. The exploration of hispidol’s mechanisms continues to expand our understanding of its prospective therapeutic applications, marking it as a compound of substantial interest in medicinal chemistry research.

Oxygen-heterocyclic compound

Oxygen-heterocyclic compound

Natural glycoside

Cyclic alcohol

Gibberellic acid A4 is a phytohormone and plant growth regulator, which is a diterpene acid derived from the fungal genus *Gibberella*. This compound functions by stimulating the production of enzymes that degrade cell wall components, allowing for cell elongation and division. Additionally, it influences the expression of genes related to growth and development processes. Gibberellic acid A4 is primarily used in agricultural and horticultural sectors to promote and enhance growth, flowering, and fruiting in plants. It is particularly effective in situations where seed germination or bolting is required, such as in the malt industry or for inducing flowering in certain ornamental plants. Furthermore, it is utilized to overcome dormancy, increase crop yields, and improve fruit size and quality in various fruit crops. Its application is strategically controlled to manipulate physiological processes, making it a valuable tool in both research and practical agricultural practices.

Carboxylic acid with ketone function

Digitoxigenin is an aglycone, which is a type of steroid structure, derived from the hydrolysis of cardiac glycosides found in plants of the Digitalis species, such as foxglove. This compound is obtained through enzymatic or chemical cleavage of glycosidic bonds present in its parent molecules, digitoxin and others, which are naturally occurring compounds in these plants. The mode of action of digitoxigenin involves inhibition of the Na⁺/K⁺-ATPase pump. This inhibition leads to an increase in intracellular sodium levels, which in turn elevates intracellular calcium concentrations via the sodium-calcium exchanger mechanism. This cascade enhances cardiac contractility, making it a foundational component in the treatment of certain heart conditions by positively affecting cardiac output. Digitoxigenin is primarily used in research settings to study cardiac physiology and pharmacology, specifically the mechanics of cardiac glycosides and their therapeutic applications. Researchers utilize this compound to dissect the biochemical pathways in cardiac tissues and understand the molecular basis of heart diseases, potentially paving the way for new therapeutic strategies.

Natural glycoside

Britannin is a sesquiterpene lactone, which is a type of organic compound found in certain plants. It is primarily derived from species within the Asteraceae family, known for its rich concentration of bioactive constituents. The mode of action of Britannin involves the inhibition of key signaling pathways and enzymes responsible for inflammatory responses and microbial growth. This unique mechanism disrupts the processes necessary for these biological functions, thereby exerting its therapeutic effects. The applications of Britannin are primarily in the realms of pharmacology and biochemistry. Its antimicrobial properties make it a candidate for research in developing treatments against various pathogenic microorganisms. Moreover, Britannin’s anti-inflammatory potential is being investigated in the context of chronic inflammatory conditions, offering a basis for therapeutic exploration. Additionally, its role in modulating certain cellular pathways opens avenues for research into cancer therapeutics, highlighting its multifaceted applications in scientific studies.

Lactone

Ketone alcohol

Esculentoside H is a naturally occurring triterpenoid saponin, which is derived from the plant Phytolacca esculenta, commonly known as the pokeweed. This compound has garnered significant interest due to its unique mode of action as an anti-inflammatory and immunomodulatory agent. By modulating cellular signaling pathways, Esculentoside H can inhibit the expression of pro-inflammatory cytokines and suppress the activation of NF-kB, a key transcription factor involved in inflammatory responses. This saponin's ability to influence such critical biochemical pathways renders it a promising candidate for the treatment of diseases characterized by excessive inflammation, such as rheumatoid arthritis and other autoimmune disorders. Additionally, ongoing research is exploring its potential as an anti-cancer agent due to its capacity to induce apoptosis in certain cancer cell lines. The pharmacological properties of Esculentoside H make it an intriguing subject for further scientific investigation and highlight its potential in therapeutic applications across various medical fields.

Natural glycoside

Carboxylic acid with alcohol function

Natural glycoside

Lactone

Acetic acid ester

Carboxylic acid with alcohol function

Acetic acid ester

Darutoside is a bioactive compound, which is a sesquiterpene lactone glycoside sourced primarily from the Siegesbeckia orientalis plant. It functions through a mechanism that enhances extracellular matrix components, particularly promoting the synthesis of collagen and elastin fibers. This action helps in reinforcing the skin's structural integrity and improving its reparative processes. Darutoside is primarily used in dermatological applications due to its potent efficacy in enhancing skin regeneration and repair. It is commonly formulated into topical treatments aimed at reducing stretch marks and scars, as well as improving skin elasticity. Its ability to stimulate fibroblast activity makes it a valuable compound in the development of advanced skin care products designed for wound healing and anti-aging. The compound's effectiveness in modulating inflammation and supporting skin recovery positions it as a significant interest to researchers focused on therapeutic developments in dermatology.

Oxygen-heterocyclic compound

Lanatoside A is a cardiac glycoside found in the plant "Lantana camara" and other plants of the family Verbenaceae. Lanatoside A is structurally characterized by an oxygenated hydroxyl group at C-3, which is present in the natural compound secoisolariciresinol. It has been shown to have inhibitory effects on enzymes involved in congestive heart failure such as myosin light chain kinase and serine/threonine protein kinase. Lanatoside A also has been shown to have immunomodulatory properties and may be beneficial for autoimmune diseases such as rheumatoid arthritis. The enzyme activities are inhibited by lanatosides at low pH values (pH 5-6) but not at high pH values (pH 7-8).

Natural glycoside