Iridioids

Natural glycoside

Natural glycoside

Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3-73.0 ug/ml).

Oxygen-heterocyclic compound

Natural glycoside

Agnuside has anti-arthritic activity, it also shows inhibition of vascular permeability and leukocyte migration in vivo.It inhibited an array of pro-inflammatory mediators (PGE(2) and LTB(4)) and T-cell-mediated cytokines (IL-2, TNF-α, IFN-γ, IL-4, IL-10, IL-17).

4'-o-Methyltaxifolin is a flavonoid compound, which is derived from natural plant sources, particularly from species within the Pinaceae family. This compound is often found as a constituent of various plant-based extracts and is known for its diverse biochemical activities. Its mode of action involves acting as an antioxidant, where it helps in scavenging free radicals, thereby reducing oxidative stress and potential cellular damage. Additionally, it can modulate various cellular pathways, contributing to its anti-inflammatory and possible anticancer activities. In scientific research and applications, 4'-o-Methyltaxifolin is extensively studied for its potential therapeutic effects, particularly in relation to cardiovascular health, neuroprotection, and anti-cancer properties. Its ability to interact with biological membranes and proteins makes it a subject of interest in drug development studies. By understanding the interactions and pathways modulated by this compound, researchers aim to explore new therapeutic avenues for treating diseases associated with oxidative stress and inflammation.

Anti-tumor agent; cytoskeleton disruptor

Harpagide analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Natural glycoside

Ajugol is a natural compound, specifically an iridoid glycoside, which is primarily sourced from plants belonging to the Lamiaceae family. It is particularly abundant in species such as Ajuga decumbens and other related Ajuga species. As a secondary metabolite, Ajugol has attracted scientific interest due to its bioactive properties. The mode of action of Ajugol involves its interaction with various biochemical pathways, contributing to its potential anti-inflammatory, antioxidant, and hepatoprotective effects. These activities are primarily attributed to its ability to modulate oxidative stress and influence enzymatic activity related to inflammatory responses. Researchers are investigating the applications of Ajugol in various fields, including pharmacology and herbal medicine. It is being explored for its potential therapeutic uses in treating conditions associated with inflammation, liver dysfunction, and oxidative stress-related disorders. While comprehensive clinical studies are necessary to fully elucidate its efficacy and safety profiles, Ajugol remains a compound of significant interest due to its natural origin and promising biological activities.

GL3 analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Sarracenin is a natural product. Sarracenin shows cytotoxic activities against tumor cells.

Gentiopicroside analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Natural glycoside

Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities. It has potent anti-apoptotic activity against renal I/R injury by suppressing the TLR4/NF-κB signaling pathway, it can protect the ischemic kidney against renal fibrosis and improve the neurological function of rats upon cerebral ischemia reperfusion injury. Picroside II enhances nerve growth factor (NGF)-induced neurite outgrowth from PC12D cells by amplifying a down-stream step of MAP kinase in the NGF receptor-mediated intracellular MAP kinase-dependent signaling pathway.

Natural glycoside

Natural glycoside

Natural glycoside

Ajugol shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3-73.0 ug/ml).

Natural glycoside

Natural glycoside

Natural glycoside

Geniposide, a major iridoid found in fruit, is widely used in Asian countries for its anti-inflammatory, and anti-apoptotic activities, the anti-apoptotic activities is due to its modulation of and -related factors (p53, Bax, Bcl-2 and Caspase-3) in LPS-induced mouse mastitis.

Shanzhiside methylester analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Geniposidic acid is a bioactive compound, which is a naturally occurring iridoid glycoside. It is primarily sourced from the fruit of Gardenia jasminoides, a plant used in traditional medicine systems. This compound exhibits its mode of action by influencing various biochemical pathways, including anti-inflammatory, antioxidant, and hepatoprotective activities. It interacts with cellular signaling processes that affect enzyme regulation and immune responses. The uses and applications of Geniposidic acid are varied due to its therapeutic potential. It has been studied for its effects on inflammatory conditions and liver protection, showing promise in mitigating oxidative stress and cellular damage. Additionally, its role in modulating immune responses presents opportunities for its use in managing disorders related to immune system dysregulation. Further research is needed to fully explore and validate the clinical applications of Geniposidic acid, though its preliminary results are promising in the context of pharmacological and therapeutic investigations.