Iridioids

Oxygen-heterocyclic compound

Natural glycoside

Morroniside has therapeutic effects on diabetic angiopathies, renal damage, lipid metabolism and inflammation and bone resorption. Morroniside can notably protect the brain from damage induced by focal cerebral ischemia which might be related to morroniside antioxidant and anti-apoptotic properties in the brain.Morroniside can decrease the level of cycloxygenase(Cox) and it may be the mechanism of morroniside on inhibiting the platelet aggregation induced by ADP in rabbits.

Sweroside and swertiamarine are main constituents in Gentian (Gentiana lutea ssp. symphyandra), Gentian has wound healing activity, seems to be mainly due to the increase in the stimulation of collagen production and the mitotic activity by sweroside and swertiamarine , respectively; they also have cytoprotective effects, which may cause a synergism in terms of wound healing activity of Gentian.

Oleuropein aglycone - 80% is a bioactive compound, a phenolic derivative, which is extracted from the leaves and fruits of the olive tree, Olea europaea. It is classified as a secoiridoid, a type of compound prevalent in certain plants, and serves as a major component of olive oil. Functioning through multiple pathways, Oleuropein aglycone exhibits significant antioxidant and anti-inflammatory activities. It achieves this by scavenging free radicals and modulating signaling pathways involved in inflammation, such as the NF-κB pathway. Furthermore, it contributes to the stabilization of cell membranes and modulation of enzymatic activities linked to oxidative stress. The uses and applications of Oleuropein aglycone - 80% are extensive in both research and therapeutic contexts. It is extensively studied for its potential protective effects against cardiovascular diseases, neurodegenerative disorders, and certain types of cancer due to its potent antioxidative properties. Additionally, it is explored for its antimicrobial and antiviral effects, indicating a broad spectrum of biological activities. This compound holds promise in nutraceutical and pharmaceutical developments aimed at enhancing human health through natural product-derived interventions.

Natural glycoside

Daphylloside, and asperuloside can be suggested as endoplasmic reticulum stress regulators.

Aucubin is an iridoid glycoside with a wide range of biological activities, including pancreas-protective, chondroprotective, antispasmodic, liver-protective, anti-inflammatory, anti-microbial, antioxidant, anti-algesic as well as anti-tumor activities. Aucubin prevents neuronal death in the hippocampal CA1 region in rats with diabetic encephalopathy, it also has protective effects on H2O2-induced apoptosis in PC12 cells. Aucubin may improve obesity-induced atherosclerosis by attenuating TNF-α-induced inflammatory responses. Aucubin suppresses hepatitis B viral DNA replication in vitro.

Loganin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

8-Epiloganic acid has antibacterial and antiviral effects.

Verminoside is a natural glycoside compound, which is derived from plant sources, particularly from the genus *Verbena* and *Buddleja*. It exhibits a range of pharmacological actions, primarily through its antioxidant and anti-inflammatory mechanisms. By scavenging free radicals and modulating inflammatory pathways, Verminoside effectively contributes to cellular protection and the mitigation of oxidative stress-induced damage. Research has shown that Verminoside has significant neuroprotective effects, making it a compound of interest in the study of neurological disorders. It is involved in the inhibition of pro-inflammatory cytokines, which are pivotal in the inflammatory response, thus potentially offering therapeutic value in conditions such as Alzheimer's disease and other neurodegenerative disorders. Additionally, its anti-bacterial and anti-viral properties extend its applicability in combating microbial infections. Ongoing studies continue to explore Verminoside's potential in various biomedical applications, focusing on its efficacy and molecular interaction pathways. The compound's plant-based origin further encourages its exploration as a potential natural therapeutic agent with minimal side effects compared to synthetic counterparts.