Lignans

Ether phenol

Natural glycoside

Fargesin may act as a β1AR antagonist to shield rat hearts from ischemia/reperfusion damage and can also enhance dyslipidemia and hyperglycemia.

(+)-Lariciresinol is a lignan, a type of polyphenolic compound, which is primarily derived from plant sources such as flaxseeds, sesame seeds, and whole grains. As a naturally occurring compound in these plants, it plays a role in their defense mechanisms against pathogens. The mode of action of (+)-Lariciresinol involves its ability to act as an antioxidant. It scavenges free radicals and reactive oxygen species, thereby reducing oxidative stress, which can damage cellular components like DNA, proteins, and lipids. This antioxidative property contributes to its potential protective effects on human health. In scientific research, (+)-Lariciresinol is studied for its various applications, particularly its role in reducing the risk of chronic diseases. It is metabolized by the human gut microbiota into enterolactone, a compound that may have estrogenic and anti-estrogenic effects, potentially influencing hormone-related diseases. Moreover, its antioxidant properties are being explored for their potential in mitigating conditions associated with oxidative stress, such as cardiovascular diseases and certain types of cancers. Overall, (+)-Lariciresinol is of significant interest in nutraceutical research and the development of functional foods.

Schizantherin B is a natural diterpenoid compound, which is isolated from the traditional Chinese medicinal plant Schizandra chinensis. It exhibits numerous biological activities due to its complex molecular structure. The primary mode of action of Schizantherin B involves modulation of multiple signaling pathways, which contributes to its anti-inflammatory, antioxidant, and neuroprotective effects. Researchers have also identified its role in inhibiting cell proliferation and inducing apoptosis in various cancer cell lines. Given its diverse bioactivities, Schizantherin B is extensively studied for potential therapeutic applications. It has shown promise in preclinical studies for the treatment of neurological disorders, owing to its neuroprotective properties. Additionally, its anti-cancer potential is being explored in experimental oncology. Schizantherin B's action as a natural bioactive compound makes it a valuable subject for further pharmacological research, particularly in exploring its efficacy and safety for future therapeutic use.

d-Epigalbacin ((-)-Zuonin A) is a naturally occurring lignin.