Lignans

Nordihydroguaiaretic acid analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage.

Oxygen-heterocyclic compound

Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.

Lactone

Kadsurin A is a naturally occurring lignan, which is a type of secondary metabolite. Derived from various plant sources, particularly those belonging to the Piperaceae family, this compound has been identified in plants used traditionally for medicinal purposes. Kadsurin A exhibits a range of bioactivities due to its ability to interact with multiple biological targets. The mode of action of Kadsurin A involves modulating various cellular pathways, including antioxidant and anti-inflammatory pathways. By influencing these pathways, it demonstrates potential therapeutic effects in the mitigation of oxidative stress and inflammation, which are critical factors in the development of numerous diseases. In terms of applications, Kadsurin A is primarily studied for its potential use in pharmacological research and drug development. Its unique bioactive profile makes it a candidate for investigating potential treatments for conditions such as cancer, neurodegenerative diseases, and cardiovascular disorders. Researchers continue to explore its mechanism of action and therapeutic efficacy through in vitro and in vivo studies, aiming to uncover its full potential in clinical settings.

Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus.

Oxygen-heterocyclic compound

Lactone