Catechin

Stability Light Sensitive Applications One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency. The gallate group causes current block, as evident by brief downward current transitions. References Ingolfsson, H., et al.: FEBS Lett., 585, 3101 (2011),

Epigallocatechin gallate, also known as EGCG, is a flavonoid that provides antioxidant properties to plants. It also inhibits telomerase, and enzyme that elongates chromosomes, and DNA methyltransferase, that transfers a methyl group to cytosine in the DNA chain.

(+)-Gallocatechin gallate is a polyphenolic compound, which is a specific type of catechin predominantly derived from green tea leaves, Camellia sinensis. It belongs to the flavonoid class of phytochemicals, known for their diverse biological activities. The compound exhibits potent antioxidant properties by scavenging free radicals and chelating metal ions, thereby reducing oxidative stress. It also modulates various signaling pathways involved in inflammation and cell proliferation. The uses of (+)-Gallocatechin gallate are extensive in scientific research, particularly in studies focusing on its potential role in preventing and treating diseases related to oxidative stress, such as cardiovascular diseases and neurodegenerative disorders. Furthermore, it is of interest in the field of cancer research due to its ability to induce apoptosis and inhibit cell growth in various cancer cell lines. These properties make it a valuable substance for exploring therapeutic applications and understanding the molecular mechanisms underpinning various health benefits.

Oxygen-heterocyclic compound

Oxygen-heterocyclic compound

(+)-Catechin is a type of polyphenolic compound, specifically a flavan-3-ol, which is a member of the broader class of flavonoids. It is derived from natural sources, predominantly found in a variety of plants such as tea leaves, cocoa, berries, and certain fruits. The compound plays a significant role as a natural antioxidant, combating oxidative stress by scavenging free radicals and chelating metal ions. The mode of action of (+)-Catechin involves its ability to donate hydrogen atoms or electrons to neutralize reactive oxygen species, thus preventing cellular damage. Additionally, it can modulate enzyme activity and influence signaling pathways related to inflammatory responses and apoptosis. In terms of uses and applications, (+)-Catechin is of considerable interest in both pharmaceutical and nutraceutical fields. It has been studied for its potential in preventing cardiovascular diseases, providing anti-inflammatory effects, and offering neuroprotective benefits. Furthermore, its role in cancer prevention and treatment has been explored, owing to its capability to induce apoptosis in tumor cells and inhibit their proliferation. Research continues to elucidate its mechanism and efficacy across different physiological contexts.

Procyanidin A2 is a type of flavonoid, which is a class of bioactive compounds extracted primarily from various plant sources such as grape seeds, cranberries, and cocoa. These compounds are known for their complex molecular structures that include oligomeric catechins. Procyanidin A2 exerts its effects by modulating oxidative stress pathways through its potent antioxidant activity. It neutralizes free radicals, thus protecting cellular components from damage and potentially ameliorating oxidative stress-related conditions. The uses and applications of Procyanidin A2 are diverse and primarily focus on its health-promoting properties. It is extensively studied for its potential role in cardiovascular health, neuroprotection, and anti-aging, attributed to its ability to enhance endothelial function and reduce inflammation markers. Additionally, Procyanidin A2 is being researched for its anticarcinogenic properties due to its potential to interfere with various stages of carcinogenesis. Its applications extend into the nutritional supplement industry, often incorporated into products aimed at promoting general health and wellness.

(-)-Gallocatechin gallate is a flavonoid compound, specifically a type of catechin, which is a phytochemical sourced primarily from tea plants, particularly green tea leaves. This compound is structurally characterized by its polyphenolic framework, which significantly contributes to its biological activity. As an antioxidant, (-)-Gallocatechin gallate functions by scavenging free radicals, thereby mitigating oxidative stress within biological systems. This mode of action is pivotal in protecting cellular components from damage induced by reactive oxygen species, making it a subject of interest in various scientific fields. In research and potential therapeutic contexts, (-)-Gallocatechin gallate is explored for its roles in reducing the risk of chronic diseases, such as cardiovascular diseases and certain types of cancer. It is also of interest in neurodegenerative disease studies due to its purported neuroprotective effects. Additionally, the compound is examined for its anti-inflammatory properties and potential benefits in metabolic disorders. As such, (-)-Gallocatechin gallate remains a valuable molecule in biochemical and clinical research, offering insights into the impact of dietary phytochemicals on health.

(+)-Catechin pentaacetate (Catechin pentaacetate) is an esterified derivative of catechin, which reduces iron and zinc transport proteins in the duodenum.

Procyanidin B3 is a flavonoid compound, which is a type of plant-derived polyphenol, sourced primarily from the seeds and skins of various fruits, especially grapes and apples. It functions primarily through strong antioxidant activity, neutralizing free radicals and reducing oxidative stress. This mode of action is fundamental to its potential therapeutic effects, as oxidative stress is a contributor to numerous chronic diseases. The uses and applications of Procyanidin B3 are varied, extending to areas such as cardiovascular health, where it is thought to support vascular function and lower the risk of disease through its anti-inflammatory properties. Additionally, Procyanidin B3 has demonstrated promise in dermatological applications, such as improving skin elasticity and reducing signs of aging due to its capability to protect collagen structures from degradation. In oncology research, it is investigated for its potential to inhibit tumor growth by impeding angiogenesis and inducing apoptosis in certain cancer cell lines. Researchers continue to explore the broader implications of Procyanidin B3 in clinical settings, given its potential to modulate various biological pathways.

Oxygen-heterocyclic compound

(-)-Gallocatechin 3-(4''-O-methyl)gallate is a naturally occurring flavonoid, which is a type of polyphenolic compound. It is derived from plant sources, specifically found in certain teas and other botanical products. This compound exhibits its mode of action primarily through its antioxidant properties, where it scavenges free radicals and inhibits oxidative stress, thereby protecting cellular systems from damage. The uses and applications of (-)-Gallocatechin 3-(4''-O-methyl)gallate are extensive in the field of scientific research, particularly within the domains of biochemistry and pharmacology. Researchers often study this compound for its potential therapeutic effects in the management of oxidative stress-related conditions, such as cardiovascular diseases and certain neurodegenerative disorders. Additionally, its role in modulating cellular signaling pathways makes it of interest for investigations into anti-cancer properties. Scientists continue to explore its bioavailability and synergistic actions with other phytochemicals to maximize its efficacy in both in vitro and in vivo studies.

Procyanidin B1 is a polyphenolic compound, which is a type of naturally occurring organic compound. It is primarily sourced from various plants, including grape seeds, apples, and cocoa. This compound is a proanthocyanidin, specifically a type of flavonoid, and is often found in the skins, seeds, and leaves of these plants. The mode of action of Procyanidin B1 involves its potent antioxidant properties. It operates by neutralizing free radicals, thereby reducing oxidative stress and potentially mitigating cellular damage. This antioxidant activity is attributed to the ability of Procyanidin B1 to donate hydrogen atoms or electrons, which stabilizes reactive oxygen species. Procyanidin B1 is utilized in scientific research due to its implications in health-related studies, particularly concerning cardiovascular protection and anti-inflammatory effects. It is being investigated for its role in enhancing vascular function, inhibiting platelet aggregation, and protecting against oxidative stress-related conditions. Moreover, its potential therapeutic applications extend to areas like skin health and neuroprotection, where its bioactive properties may offer significant benefits. These diverse applications continue to drive scholarly interest in this compound.

Oxygen-heterocyclic compound

Procyanidin B2 is a type of polyphenol, specifically a flavonoid compound, which is derived from plant sources such as grape seeds, apples, and cacao beans. This compound is characterized by its dimeric structure, consisting of two epicatechin units linked through a specific bond. The mode of action of Procyanidin B2 involves its function as a potent antioxidant, which allows it to neutralize free radicals and reduce oxidative stress at the cellular level. Additionally, it influences various signaling pathways, modulating enzyme activity and gene expression related to inflammation and cell survival. Procyanidin B2 is extensively studied for its potential therapeutic applications. Its antioxidant properties make it a candidate for reducing the risk of chronic diseases associated with oxidative damage, such as cardiovascular diseases, cancers, and neurodegenerative disorders. Furthermore, Procyanidin B2 has been investigated for its ability to enhance vascular health, improve skin conditions, and contribute to overall metabolic regulation. Its role in modulating inflammatory pathways also highlights its potential in managing conditions like arthritis. Current research continues to explore the diverse mechanisms and potential health benefits of this compound within various biological systems.

Procyanidin B3 analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

(+)-Gallocatechin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

(-)-Gallocatechin gallate analytical standard provided with w/w absolute assay, to be used for quantitative titration.

(-)-Epicatechin gallate analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Oxygen-heterocyclic compound

Catechin 7,4'-di-O-gallate is a naturally occurring flavonoid compound, which is derived from various plants, particularly those rich in catechins, such as tea leaves and certain fruits. As a member of the polyphenol class, it is known for its powerful antioxidant properties, which enable it to neutralize free radicals and mitigate oxidative stress. Additionally, its structure allows for strong anti-inflammatory effects by modulating signaling pathways and inhibiting the production of inflammatory mediators. The compound is primarily used in research settings for exploring its therapeutic potential in various health conditions. Studies suggest it may play a role in cardiovascular health protection, cancer prevention, and neuroprotection. Its ability to interact with various molecular targets makes it a subject of interest for further pharmacological studies, aiming to develop strategies against oxidative and inflammatory-related diseases.

(-)-Epiafzelechin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Procyanidin C1 analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

(-) Gallocatechin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Epicatechin-(2beta->5,4beta->6)-ent-epicatechin is a type of flavonoid dimer, which is derived from natural plant sources, particularly in some fruits and nuts known for their rich polyphenolic content. This compound belongs to the class of procyanidins, which are well-known for their potent antioxidant properties. The mode of action involves the scavenging of free radicals and modulation of oxidative stress pathways, as well as interaction with key enzymes and receptors within the body. Such mechanisms contribute to its potential in reducing oxidative damage and influencing metabolic processes. In scientific research, Epicatechin-(2beta->5,4beta->6)-ent-epicatechin is utilized for its possible applications in health and disease prevention. Its antioxidant capabilities make it a subject of interest for studies focused on cardiovascular health, diabetes, and neurodegenerative diseases. Researchers explore its effects on cell signaling pathways, gene expression related to oxidative stress, and its ability to influence endothelial function and blood flow. The compound's role in improving metabolic health and its potential therapeutic benefits continue to be significant areas of investigation within pharmacology and nutraceutical development.

(-)-Epigallocatechin gallate analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Oxygen-heterocyclic compound

Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea.

Oxygen-heterocyclic compound

(-) Catechin gallate analytical standard provided with w/w absolute assay, to be used for quantitative titration.

(-)-Epigallocatechin is a polyphenolic compound, which is a type of catechin, primarily found in the tea plant, Camellia sinensis. This compound is abundant in green tea leaves and is recognized for its potent antioxidant properties. The source of (-)-Epigallocatechin can be traced back to the biosynthesis pathway in plants, where it contributes to the plant's defense mechanisms against environmental stressors. The mode of action of (-)-Epigallocatechin involves the neutralization of free radicals, thereby protecting cells from oxidative damage. It scavenges reactive oxygen species (ROS) and chelates metal ions, thereby preventing the formation of reactive entities that initiate inflammation and DNA damage. This activity makes it a compound of interest in various scientific studies aiming to understand its biochemical and molecular impacts on human health. The uses and applications of (-)-Epigallocatechin are diverse, primarily studied for its potential benefits in reducing the risk of chronic diseases such as cardiovascular diseases, certain cancers, and neurodegenerative disorders. It is also explored for its anti-inflammatory, antiviral, and antimicrobial properties. Research continues to explore its role in modulating signal transduction pathways, cell cycle regulation, and apoptosis in various cell types, highlighting its significance in the field of medicinal chemistry and therapeutic development.

Oxygen-heterocyclic compound

Procyanidin A1 analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Oxygen-heterocyclic compound

Procyanidin B2 analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Oxygen-heterocyclic compound

Oxygen-heterocyclic compound

Epigallocatechin gallate, also known as EGCG, is a flavonoid that provides antioxidant properties to plants. It also inhibits telomerase, and enzyme that elongates chromosomes, and DNA methyltransferase, that transfers a methyl group to cytosine in the DNA chain.

(+)-Epicatechin (Dexepicatechin) is a natural product and an antioxidant agent.

(-)-Epicatechin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Procyanidin B4 is a type of proanthocyanidin, which is a class of flavonoids. This compound is predominantly derived from various plant sources, notably grape seeds and certain fruits like apples. Its mode of action is primarily through its antioxidant properties, which involve scavenging free radicals and reducing oxidative stress at the cellular level. Procyanidin B4 operates by stabilizing free radicals with its phenolic hydroxyl groups, thereby inhibiting lipid peroxidation and protecting cellular components such as DNA, proteins, and lipids from oxidative damage. The uses and applications of Procyanidin B4 are mainly in biomedical and nutraceutical research. It has been studied for its potential benefits in cardiovascular health, particularly in promoting vascular function and reducing inflammation. Moreover, its role in skin health has garnered attention, with research focusing on its potential to protect against UV-induced damage and support collagen synthesis. In addition, Procyanidin B4 is explored for its neuroprotective effects, illustrating promise in mitigating neurodegenerative conditions. These diverse bioactivities make Procyanidin B4 a significant compound of interest in ongoing scientific research.

(+)-Catechin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

3'-O-Methylcatechin is a naturally occurring flavonoid, which is derived from various plant sources, such as tea and certain fruits. It belongs to the class of compounds known as catechins, which are polyphenolic compounds widely recognized for their beneficial health effects. The methylation at the 3' position distinguishes it from other catechins, potentially influencing its bioavailability and biochemical activity. This compound functions primarily as a potent antioxidant, scavenging reactive oxygen species and thereby protecting cells from oxidative stress. Its ability to modulate various signaling pathways and inhibit the oxidation of low-density lipoproteins (LDL) highlights its significance in preventing cellular damage and supporting cardiovascular health. 3'-O-Methylcatechin is utilized in numerous research contexts, particularly in studies investigating its role in cancer prevention, cardiovascular health, and neuroprotection. Scientists study its effects on metabolic pathways, gene expression, and enzyme activity to uncover potential therapeutic applications. Due to its antioxidant properties, it is also explored for its implications in aging and age-related diseases. Understanding the mechanisms and effects of 3'-O-methylcatechin helps enhance our knowledge of flavonoid interactions in biological systems.

(-)-Catechin is a flavonoid compound, classified as a polyphenolic antioxidant, which is predominantly derived from plant sources such as tea leaves, cocoa, and various fruits. Its molecular structure allows it to scavenge free radicals and chelate metal ions, exhibiting potent antioxidant properties. This reactive nature contributes to its ability to modulate signaling pathways and inhibit enzymatic activities related to oxidative stress and inflammation. The primary applications of (-)-Catechin include its use in biochemical research to explore mechanisms of oxidative damage and potential therapeutic interventions. It is investigated for its potential protective effects against cardiovascular diseases, due to its capacity to improve endothelial function and reduce LDL oxidation. Additionally, (-)-Catechin is studied for its anti-carcinogenic properties, owing to its ability to induce apoptosis and inhibit proliferation in certain cancer cell lines. Its neuroprotective benefits are also under examination, considering its influence on neuronal survival and cognitive function. Through its diverse molecular interactions, (-)-Catechin offers significant insights into the pathways governing cellular health and disease prevention, making it a vital subject of study in the field of biomedical sciences.

(+)-Gallocatechin is a flavonoid, which is a type of polyphenol compound, naturally found in a variety of plant sources such as tea leaves, cocoa, and certain fruits. It is structurally related to other catechins, sharing similar properties and biological activities. As an antioxidant, (+)-Gallocatechin acts by scavenging free radicals, thereby inhibiting oxidative stress-a process linked to various chronic diseases and aging. In addition to its antioxidative properties, it plays a role in modulating enzyme activities and signaling pathways. This influence extends into areas such as cholesterol metabolism and immune response modulation. The compound has been explored for its potential applications in cardiovascular health, cancer prevention, and neuroprotective strategies, aligning with a broader interest in dietary polyphenols for health maintenance and disease prevention. Research on (+)-Gallocatechin continues to uncover its complex interactions within biological systems, making it a topic of interest in pharmacology and nutritional science. Its multifaceted roles suggest promising avenues for therapeutic development, although more studies are needed to fully understand its mechanisms and efficacy in clinical settings.

(-)-Gallocatechin is a type of flavan-3-ol, specifically a catechin, which is a subtype of polyphenol. This compound is naturally sourced from various plants, particularly abundant in green tea leaves. It is part of the broader catechin family, known for possessing potent antioxidant potential. The mode of action of (-)-Gallocatechin primarily involves its ability to neutralize free radicals, which are unstable molecules that can cause oxidative stress and subsequent damage to cells. Its antioxidant properties help in reducing such oxidative stress by donating electrons to free radicals, thus stabilizing them and preventing cellular damage. The uses and applications of (-)-Gallocatechin are extensive, particularly in scientific research related to health and nutrition. It's being studied for its potential roles in various biological processes, including anti-inflammatory effects and cardiovascular health. Additionally, its presence in the diet as part of tea and other plant-based foods makes it a compound of interest for nutritional studies focusing on disease prevention and health promotion. The exploration of (-)-Gallocatechin in pharmacological contexts is also ongoing, as its antioxidant properties could contribute to therapeutic strategies against oxidative stress-related conditions.

Procyanidin B1 analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Oxygen-heterocyclic compound

Oxygen-heterocyclic compound

Oxygen-heterocyclic compound

(-)-Epigallocatechin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

(±)-Catechin is a type of flavonoid, a class of compounds known for their diverse range of biological activities. It is primarily sourced from a variety of plants, including tea leaves, cocoa, and certain fruits, where it exists as a natural antioxidant. The mode of action of (±)-catechin involves scavenging free radicals, thereby protecting cells from oxidative stress and potential damage. This protective mechanism is largely attributed to its polyphenolic structure, allowing it to neutralize reactive oxygen species (ROS). In scientific research, (±)-catechin is utilized for its antioxidative, anti-inflammatory, and potential cardiovascular protective effects. It is widely studied in the context of its potential health benefits, including reducing the risk of chronic diseases such as heart disease and certain types of cancer. Additionally, (±)-catechin is investigated for its role in modulating lipid metabolism and improving vascular function. Its applications extend to food science, where it is considered for enhancing the nutritional profile of dietary products and improving shelf life through its antioxidative properties. The compound also finds relevance in the development of functional foods and nutraceuticals.

(-)-Epicatechin gallate is a type of catechin, which is a polyphenolic compound primarily sourced from green tea leaves. This compound is known for its potent antioxidant properties, which effectively neutralize free radicals, thereby reducing oxidative stress and potentially preventing cellular damage. The mode of action of (-)-Epicatechin gallate involves the scavenging of reactive oxygen species and the modulation of signaling pathways related to cell survival and apoptosis. It can also influence the activity of various enzymes and receptors involved in cellular metabolism and stress responses. In terms of applications, (-)-Epicatechin gallate is extensively studied for its potential health benefits, including cardiovascular protection, anti-inflammatory effects, and anticancer properties. Its ability to inhibit lipid peroxidation and modulate endothelial function makes it a subject of interest in cardiovascular research. Moreover, it is being explored for its role in neuroprotection and metabolic health, given its impact on insulin sensitivity and glucose metabolism. Scientists continue to investigate its therapeutic potential in various fields, aiming to harness its bioactive properties for disease prevention and health promotion.

Procyanidin A2 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

(+)-Catechin hydrate is a chiral flavonoid, which is a type of natural polyphenol compound. It is primarily sourced from various plants, including tea leaves, cocoa, and certain fruits. As an integral component of the flavonoid group, (+)-Catechin hydrate exhibits strong antioxidant activity, primarily through its ability to scavenge free radicals and chelate metal ions, thereby mitigating oxidative stress within biological systems. The significant role of (+)-Catechin hydrate in scientific research stems from its wide-ranging biological activities. It is extensively used in studies related to cardiovascular health, due to its potential in reducing oxidative stress and modifying lipid profiles. Furthermore, it has been investigated for its anti-inflammatory and anticancer properties, as well as its neuroprotective effects. These properties make it a subject of interest in pharmaceutical and nutraceutical applications. Research exploring its impact on metabolic syndromes and its potential in enhancing exercise performance also highlights its versatile applicability. This compound continues to be pivotal in advancing our understanding of polyphenol-related health benefits.

(-)-Epicatechin is a flavonoid compound, which is a type of polyphenol that can be found in various natural sources such as cacao beans, green tea, and certain fruits. Structurally, it belongs to the class of catechins and is known for its antioxidant properties. Its mode of action involves the scavenging of free radicals and modulation of various signaling pathways relevant to oxidative stress. (-)-Epicatechin has been shown to influence endothelial function by enhancing nitric oxide (NO) production, leading to improved vascular health. Moreover, it can interact with different cellular proteins, affecting pathways associated with inflammation and cell survival. The applications of (-)-Epicatechin are diverse, with a particular focus on its potential cardiovascular benefits. Scientific studies suggest that it may contribute to lowering blood pressure, improving lipid profiles, and offering protection against atherosclerosis. Additionally, due to its beneficial impact on muscle function and insulin sensitivity, (-)-Epicatechin is being investigated for its role in metabolic health, including diabetes management. Further research is ongoing to elucidate its comprehensive bioactivity and therapeutic potential.

(+)-Gallocatechin gallate analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.