Vitamins

Riboflavin is a water-soluble vitamin, which is derived primarily from dietary sources such as milk, eggs, nuts, and green vegetables. As a precursor to coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), riboflavin plays a crucial role within the cellular metabolic pathways. These coenzymes are essential for redox reactions occurring in mitochondrial energy metabolism, particularly within the electron transport chain. Riboflavin is imperative for the oxidative metabolism of carbohydrates, amino acids, and fats, facilitating the transfer of electrons. Additionally, it is involved in the regeneration of glutathione, an important cellular antioxidant, thereby contributing to the reduction of oxidative stress and maintaining cellular homeostasis. Beyond its metabolic roles, riboflavin is also significant in the metabolism of other vitamins, like niacin and vitamin B6. In scientific research and clinical fields, riboflavin is utilized to explore its therapeutic potential, including the management of migraines, its use as a biomarker for nutritional status, and in studies concerning mitochondrial disorders. Its fundamental role in cellular processes makes it an important subject of investigation in biochemistry and molecular biology.

Stability Light Sensitive, Temperature Sensitive Applications A labelled metabolite of Vitamin D, a possible anti-inflammatory steroid. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Boyan, B., et al.: Steroids, 66, 363 (2001), Holick, M., et al.: J. Cell Biochem., 88, 296 (2003), Vogeser, M., et al.: Clin. Chem., 50, 1415 (2004), Singh, R., et al.: J. Clin. Endocrinol. Metab., 91, 3055 (2006),

Stability Light Sensitive, Temperature Sensitive Applications The biologically active form of vitamin D3. Calcium regulator; vitamin (antirachitic); antihyperparathyroid; antineoplastic; antipsoriatic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Myrtle, J.F., et al.: J. Biol. Chem., 245, 1190 (1970), Lawson, D.E.M., et al.: Nature, 230, 228 (1971), Norman, A.W., et al.: Science, 173, 51 (1971), Suda, T., et al.: Vitamins, 45, 175 (1972), Muindi, J.R., et al.: Clin. Pharmacol. Ther., 72, 648 (2002),