Glycerophospholipids / Phospholipids

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1-O-Hexadecyl-rac-glycero-3-phosphocholine is a speciality chemical that is used as a reagent in the synthesis of complex compounds. It has been shown to be a useful scaffold for the synthesis of novel and structurally diverse analogues of phospholipids. 1-O-Hexadecyl-rac-glycero-3-phosphocholine is also used as a reaction component in the synthesis of fine chemicals, such as antibiotics and antihistamines, which are active ingredients in pharmaceuticals.

DAPC; uncharged cell membrane phospholipid

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L-alpha-Phosphatidylcholine distearoyl, also known as 1,2-Distearoyl-sn-glycero-3-phosphocholine or DSPC, is an uncharged cell membrane phospholipid. It is one of a number used in membrane research. DSPC is also a formulation component for drugs as part of liposomal delivery systems, including for mRNA vaccines such as those used against COVID-19 (SARS-CoV-2).

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1,2-Dioleoyl-sn-glycero-3-phosphocholine is a phospholipid that has been shown to have antimicrobial activity. It has been observed to inhibit the growth of bacteria by disrupting cell membrane systems and inhibiting protein synthesis. 1,2-Dioleoyl-sn-glycero-3-phosphocholine is able to permeate membranes and enter cells, where it interacts with the cell nuclei and inhibits DNA synthesis. This compound is also found in biological studies as a growth factor for neutrophils and as a model system for studying the mechanism of action of antimicrobial peptides. The phase transition temperature of this compound is low, making it useful for studies in chemical biology.

1,2-Di-O-dodecyl-rac-glycerol (DODG) is a fatty acid that is produced by the hydrolysis of 1,2-diacylglycerols in the intestines. It has been shown to be responsible for chronic pain and pancreatitis. The cytosolic calcium levels are increased as a result of DODG binding to the cytosol, leading to increased production of reactive oxygen species and activation of nuclear factor kappa B (NFκB). This leads to an increase in cytokine tnf-α and prostaglandin E2 in pancreatic cells. Inhibition of pancreatic lipase activity may also contribute to the development of pancreatitis. DODG binds to the exocrine pancreas by blocking its enzymes, causing abdominal pain and pancreatitis.

Palmitoyl-DL-carnitine is a natural compound found in the body that plays an important role in energy metabolism. It has been shown to significantly increase intracellular calcium levels and activate the enzyme activity of phospholipase A2, which is responsible for the release of arachidonic acid from membrane phospholipids. Palmitoyl-DL-carnitine also has an effect on cellular energy metabolism by increasing mitochondrial membrane potential and decreasing reactive oxygen species production. Palmitoyl-DL-carnitine also protects against muscle cell death by inhibiting apoptosis and necrosis, which are usually triggered by pharmacological agents such as rotenone or bafilomycin A1.

Lecithin is a fat-like substance that consists of a glycerol molecule with three fatty acids attached to it. It is found in the membranes of cells and has many biological functions, including acting as an emulsifier and being involved in the uptake of cholesterol from the blood stream. Lecithin also has antioxidant properties, which have been shown by its ability to inhibit oxidation of α-tocopherol. Lecithin can be used as a therapeutic agent for inflammatory diseases and other conditions linked to oxidative stress.

Palmitoyldocosahexaenoyl phosphatidylcholine (PC-S) is a fatty acid with six double bonds. It has been shown to induce osteogenic genes in human macrophages and can be used as a potential therapeutic agent for the treatment of bone diseases. PC-S also has anti-inflammatory properties, which is due to its ability to inhibit secretory phospholipase A2 (sPLA2). PC-S is structurally similar to the polyunsaturated fatty acid linoleic acid and has been found to have reactive properties. PC-S may be used as an adjuvant therapy for cancer and other diseases, such as Alzheimer's disease. Clinical studies are currently being conducted.

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POVPC is a zirconium oxide that has been used in the production of artificial joints, dental implants, and bone replacements. It has also been used to coat catheters and other medical devices to prevent infection. POVPC is an antioxidant with strong anti-inflammatory properties, inhibiting the release of inflammatory mediators such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). It also inhibits nuclear factor kappa B (NFκB), which is involved in the inflammatory response. The use of POVPC has been shown to reduce atherosclerotic lesion size in mice by inhibiting the production of reactive oxygen species and reducing oxidative stress.

1-Palmitoylglycol-2-phosphocholine is a phospholipid that can be used as an intermediate to produce various chemicals, such as surfactants and plastics. It has a variety of useful properties and can be used in many different reactions. The chemical is soluble in organic solvents, making it easy to work with. 1-Palmitoylglycol-2-phosphocholine is not toxic and does not react with other compounds or irritate the skin. It has a high purity level and is a versatile building block for the production of research chemicals.

1,2-Dipalmitoyl ethylene glycol is a polylactic glycol ester that has been used as a pharmaceutical preparation for the treatment of burns. It is used as a substrate film for the manufacture of tablets and other pharmaceutical preparations. 1,2-Dipalmitoyl ethylene glycol is an ester compound with two fatty acids attached to a glycol moiety. It reversibly expands when heated and can be used in some formulations as a thickener or plasticizer. The genotoxic potential of 1,2-dipalmitoyl ethylene glycol has not been studied extensively, but it has shown no evidence of carcinogenicity in animal studies.

Please enquire for more information about 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-lactosyl ammonium including the price, delivery time and more detailed product information at the technical inquiry form on this page

Corydine is a diterpenoid alkaloid that has been isolated from the Chinese herb Stephania. It is an antimicrobial agent and has been shown to inhibit the growth of mouse tumor cells with a potency comparable to cryptopine and stephania. Corydine is structurally similar to protopine, which has been shown to have anticarcinogenic properties in mice. Protopine is also found in the genus Stephania. The chemical structure of corydine was determined by using gas chromatography-mass spectrometry analyses, showing that it contains p-hydroxybenzoic acid. This compound may be responsible for its anticarcinogenic activity.

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Lecithin is a phospholipid normally derived from sources like soybeans, sunflower seeds, or egg yolks. Widely used as an excipient in pharmaceutical formulations, lecithin is used as an emulsifier to ensure a uniform dispersion of the active ingredients, as a solubilizing agent to enhance the bioavailability of poorly water-soluble drugs, and as a dispersing agent in liposomes or lipid-based drug delivery systems.

1-Myristoyl-rac-glycero-3-phosphoethanolamine is a versatile building block that is used in the synthesis of complex compounds and research chemicals. It has been used as a reagent and a speciality chemical, and has been shown to be useful as an intermediate in the synthesis of other compounds. 1-Myristoyl-rac-glycero-3-phosphoethanolamine can also be used as a reaction component or a useful scaffold for chemical reactions.

1,2-Dipalmitoyl-sn-glycero-3-phosphoserine is a versatile building block that can be used in the synthesis of many different compounds. It is a fine chemical and research chemical that has been shown to be useful in the synthesis of various complex compounds. 1,2-Dipalmitoyl-sn-glycero-3-phosphoserine is also a speciality chemical and reagent that is available at high quality. This compound has been shown to have many uses as a reaction component or scaffold in organic synthesis.

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