Nucleosides

2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one is a modified nucleoside analog with the following structure: the core heterocyclic structure is a fused imidazole-triazine ring, there is a 2-amino group at position 2 of the imidazole ring and it has a 2-deoxy-β-D-ribofuranose sugar attached at the 8-position of the heterocyclic ring, making it structurally related to DNA nucleosides.

(E)-2'-Deoxy-2'-(fluoromethylene)cytidine is a cytostatic compound that inhibits DNA synthesis in tumor cells. It has been shown to be more potent than tezacitabine and hl-60 cells, as well as being less toxic than benzimidazole compounds. This analog of cytosine has been shown to have potent antitumor activity against carcinoma cell lines and myeloid leukemia cell lines. The oral prodrug form of this drug has been shown to be an effective treatment for myeloid leukemia in mice.

N2-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-guanosine 3'-CE phosphoramidite is a modified nucleoside that can be used to synthesize DNA oligonucleotides. It is an anticancer agent that inhibits the proliferation of cancer cells by interfering with the synthesis of RNA and DNA. N2-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT guanosine 3'-CE phosphoramidite is also a antiviral agent that has been shown to inhibit viral replication at a posttranscriptional level. This nucleoside has a high purity and high quality, and it is novel due to its chemical structure.

N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a modified nucleoside with anticancer and antiviral properties. It is used in the synthesis of oligonucleotides as an activator, DNA or RNA. This product is also used as a phosphoramidite for the preparation of oligonucleotides. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT cytidine has a CAS Number of 8125687.

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N4-Acetyl-3'-O-acetyl-2'-deoxycytidine is a novel, modified nucleoside that contains a phosphoramidate linkage. It has been shown to have anticancer and antiviral properties. N4-Acetyl-3'-O-acetyl-2'-deoxycytidine is also an activator of the immune system and has been shown to be effective against HIV.

8-Aminoadenosine-5'-triphosphate lithium salt - 100mM aqueous solution is an antiviral and anticancer agent that acts by inhibiting the synthesis of DNA. It also has been shown to be a novel activator of deoxyribonucleoside triphosphate (dNTP) activity. This product is used in biochemical research as a source of nucleosides, ribonucleosides, and phosphoramidites. It is also used in antisense therapy for the treatment of HIV infection.

Amidite designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.

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2'-Deoxy-5-fluoroadenosine is a nucleoside that is used in the synthesis of DNA and RNA. It has antiviral activity and can be used as an anticancer agent. This nucleoside is synthesized by reacting 2'-deoxyadenosine with 5-fluorouracil in a high-quality, high purity environment under stringent conditions. 2'-Deoxy-5-fluoroadenosine has also been shown to have antiretroviral activity against HIV and hepatitis B virus.

5-Azauridine is a nucleoside that is synthesized from uridine. It inhibits protein synthesis by inhibiting the enzyme orotate phosphoribosyltransferase. This enzyme converts orotic acid to orotidine 5′-monophosphate, which is a precursor for the synthesis of pyrimidines and purines. 5-Azauridine has been shown to have an inhibitory effect on leukemia cells in tissue culture and also has been shown to inhibit leukemic mice with an efficacy of 50%. This drug may be useful for the treatment of solid tumours as it inhibits protein synthesis.

8-Bromo-9-(beta-D-xylofuranosyl)guanine (8BrG) is a modified nucleoside that has been shown to inhibit DNA and RNA synthesis in cells. This compound is also an antiviral agent with activity against herpes simplex virus type 1, herpes simplex virus type 2, and HIV. 8BrG inhibits the production of viral diphosphate and ribonucleosides by competitive inhibition of cellular enzymes involved in nucleotide biosynthesis. 8BrG is not active against bacterial cells, which lack these enzymes. 8BrG is synthesized by the addition of a bromine to the 9th position of guanine. It is a novel nucleotide that may have applications as an activator for other drugs or as a cancer treatment.

2'-Deoxy-5-hydroxymethylcytidine is a nucleoside analog that inhibits the enzyme thymidylate synthase. The inhibition of this enzyme leads to a deficiency in the production of thymine, which is essential for DNA synthesis. 2'-Deoxy-5-hydroxymethylcytidine has been shown to be an effective anti-cancer agent in vitro and in vivo. It can also be used as a potential biomarker for cancer and can be used as a polymerase chain reaction (PCR) primer for detection of cancer tissue. This drug binds to the polymerase enzyme, preventing it from performing its function to replicate DNA, thereby halting cell division and causing cell death.

Anti-viral; anti-neoplastic

2',3'-Dideoxyxanthosine is a purine nucleoside analog that inhibits the production of human immunodeficiency virus (HIV). It has potent activity against HIV and is more potent than other drugs in its class. This drug also inhibits the growth of cells by preventing the synthesis of DNA, RNA, and proteins. 2',3'-Dideoxyxanthosine has shown to be an effective treatment for HIV infection.

2-Chloro-3-deazaadenosine is an antiviral drug that inhibits the synthesis of DNA by acting as a competitive inhibitor for adenosine. It has been shown to be effective in the treatment of hepatitis B virus and herpes simplex virus infections. 2-Chloro-3-deazaadenosine prevents the incorporation of the natural nucleoside adenosine into DNA, which leads to inhibition of viral replication and cell division. This drug also has been shown to inactivate liver cells in bovines, which may account for its toxicity. The synthesis of 2-chloroadenosine is difficult and laborious due to its glycosylation, making it more expensive than other analogues that are more easily synthesized.

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2'-Methyl-adenosine-(Bz)-succinyl-CPG; 500 Å (RNA) is a synthetic nucleotide that has antiviral and anticancer properties. It is a novel nucleotide with the phosphate group at the 2' position of the ribose sugar, which can be phosphorylated to form monophosphate or diphosphate. This product is highly purified and has been shown to have antiviral activity against HIV and anticancer activities in vitro.

2'-Deoxy-5-propynylcytidine is an acidic oligodeoxynucleotide that is a pharmacophore. It has been shown to bind to the herpes simplex virus and stabilize the viral DNA. 2'-Deoxy-5-propynylcytidine has also been used in conjugates to target cells for drug delivery and as ligands for affinity chromatography. This cytosine analog interacts with gold nanoparticles by ion-exchange, which has been used in enzyme immobilization and residue analysis.

Lutonarin is a naturally occurring compound in the plant Pueraria lobata. It has been shown to have anti-cancer properties and can be used as an alternative to radiation therapy for cancer treatment. Lutonarin is a membrane-hyperpolarizing agent that is able to pass through the cell membrane, leading to membrane hyperpolarization. Lutonarin also inhibits the production of gamma-aminobutyric acid (GABA), which leads to increased cell proliferation and inhibition of root formation. Lutonarin has been found to inhibit enzyme activities, such as glucose monitoring and protocatechuic acid, phenolic acid, and crystalline cellulose degradation. This leads to reduced glucose levels in blood plasma and reduced degradation of polysaccharides in roots.

1-(2,3,5-Tri-O-acetyl-b-D-ribofuranosyl)nicotinamide is a phosphoramidite that is used for the synthesis of DNA and RNA. It has antiviral and anticancer properties. This compound binds to DNA and inhibits the activity of topoisomerase II, which leads to cell death by inhibiting the production of proteins vital for cell division. 1-(2,3,5-Tri-O-acetyl-b-D-ribofuranosyl)nicotinamide also prevents the replication of viral RNA by inhibiting reverse transcriptase.

N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer is a novel deoxyribonucleoside monomer. It is an antiviral, activator and high purity compound that can be used as a building block for the preparation of modified oligodeoxynucleotides. N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer is synthesized by reacting 7'-O-(benzoyl)ribose with trityl chloride in the presence of morpholine to form the corresponding benzyl ester.

N2-Isobutyryl-O6-(4-pivaloyloxybenzyl)-7’-OH-N-trityl-morpholino guanine is a phosphoramidite nucleoside that is used as a building block in the synthesis of oligonucleotides. N2-Isobutyrylguanosine is available as a high purity, high quality, and novel nucleoside that can be used in anticancer therapy. It has been shown to inhibit the growth of human cancer cells without affecting normal cells. This drug also inhibits DNA and RNA synthesis by inhibiting the enzyme ribonucleotide reductase.

5-Bromo-2'-deoxy-4-thiouridine is a high purity, diphosphate nucleoside with novel anticancer activity. It is a potent activator of the transcription factor NF-kappaB and inhibits the proliferation of cancer cells. 5-Bromo-2'-deoxy-4-thiouridine has been shown to be an effective antiviral agent against HIV and hepatitis B virus in vitro. This compound also inhibits the synthesis of DNA and RNA in human cells, which may be due to its ability to inhibit thymidylate synthase. 5-Bromo-2'-deoxy-4-thiouridine is not active against bacterial cells because they lack thymidylate synthase.

N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-deoxycytidine is a monophosphate nucleoside analogue. It has antiviral and anticancer properties, as well as the ability to activate DNA synthesis. This product is synthesized from 2'-deoxycytidine and 4-benzoyl chloride in the presence of tert-butyldimethylsilyl chloride. It is available for sale as a white powder with a purity of 99%.

1-Methylxanthosine is a caffeine derivative that was first isolated from xanthosine in 1887. It is an acidic compound and has been shown to have antiinflammatory effects, which may be due to its inhibition of prostaglandin synthesis. 1-Methylxanthosine has also been shown to have anticarcinogenic properties, possibly through the inhibition of the enzyme nitrous oxide synthase.

5'-O-tert-Butyldimethylsilyl-D3-thymidine 3'-CE phosphoramidite is a novel, modified ribonucleoside which is an activator of DNA synthesis and antiviral. It is synthesized by the reaction of 5'-O-tert-butyldimethylsilyl-D3-thymidine with 3'-chloroethoxycyanoethyl phosphate in the presence of tetrazole. The CAS number for this compound is 108881-52-2. This product has been shown to inhibit cancer cells through the inhibition of RNA synthesis and activation of DNA synthesis, as well as inhibiting viral replication.

2'-O-Methylguanosine is a nucleoside that contains a 2'-O-methyl group at the 2' position of the ribose. It is a component of many nucleic acids and is usually found as a minor component in RNA. 2'-O-Methylguanosine has been shown to be an inhibitor of DNA polymerase and an activator of RNA polymerase, which may be due to its ability to form hydrogen bonds with the phosphate backbone. This compound has also been shown to act as a competitive inhibitor for both wild-type and mutant bacterial strains, suggesting that it can inhibit DNA synthesis in bacteria by binding to the enzyme's active site. 2'-O-Methylguanosine is present in relatively high concentrations in tissues, such as liver and muscle, where it is involved in metabolism or energy production. The optimum concentration for detection by analytical methods varies depending on the type of detector used.

2-Thiothymidine is a hydrogen bond donor and acceptor that can be used as a substitute for thymine in the synthesis of DNA. 2-Thiothymidine has been shown to have successful in vivo treatment against bladder cancer and skin cells, as well as photochemical properties. It has been shown to inhibit the growth of prostate cancer cells by inhibiting DNA synthesis. 2-Thiothymidine binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming. 2-Thiothymidine is a nucleoside analog that is substituted for thymine during DNA synthesis. It inhibits the growth of prostate cancer cells by inhibiting DNA synthesis. It binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming.

Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution is a novel, synthetic and highly purified ribonucleoside phosphoramidite. It is used as an activator of nucleic acid synthesis in the preparation of DNA and RNA. Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution has been shown to be effective against various types of cancer cells, including leukemic cells and breast cancer cells. The drug also inhibits the replication of human immunodeficiency virus (HIV) and herpes simplex virus type 2 (HSV-2).

3'-O-Amino-2'-deoxyadenosine is a novel nucleoside analogue with antiviral and anticancer properties. It was shown to be an activator of the deoxyribonucleotide synthesis process, leading to inhibition of DNA replication in vitro. This compound is synthesized by the reaction of phosphoramidites with 3'-O-amino-2'-deoxyadenosine.

2'-Deoxy-2'-fluorocytidine-5'-triphosphate tetralithium is a modified nucleoside analog where the base is cytosine, the sugar is deoxyribose with a fluoro modification at the 2' position, and the molecule is phosphorylated at the 5' position with a triphosphate group.

4-Amino-6-methyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone (4AMD) is an adenosine analog that is fluorescent. 4AMD is not hydrolyzed by adenosine deaminase and has a higher affinity for the A1 receptor than for the A2a receptor. This makes it a useful probe for the study of adenosine mediated, yields, and analogs. The fluorescence properties of 4AMD were studied in different solvents at various temperatures to monitor the interaction of 4AMD with catalysis. The monomeric form of 4AMD was used to measure its fluorescence properties.

1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-octadecanoyl)-cytosine is an antiviral nucleoside that is synthesized from a 4′ azidodecanoyl derivative of cytosine. It has been shown to be effective against herpes simplex virus type 1 and 2 (HSV1, HSV2), varicella zoster virus (VZV), and Epstein Barr Virus (EBV). The antiviral mechanism of action for this compound is not known.

8-(4-Aminophenyl)-2'-deoxyguanosine is an Activator that has novel properties. It is a diphosphate of 8-(4-Aminophenyl)thymidine and is also known as 8-APT. It has been shown to have anticancer and antiviral activity in animal models, and it may be a potential treatment for HIV infection. The chemical name for 8-APT is 2'-deoxyguanosine, 8-(4-aminophenyl)-, (8R*,9S*)-.

2,4,5,6-Tetraaminopyrimidine 2HCl is a chemical compound that belongs to the group of pyrimidines. It is a colorless solid with a melting point of 178.2°C and a boiling point of 339.8°C. This compound can be obtained by reacting 2,4,5-trichloropyrimidine with potassium cyanide in acetic acid solution or by heating 2,4-diaminopyrimidine with ammonium chloride and sodium nitrate in water. In the liquid chromatography process this compound is used as an analytical reagent for determining the purity and identity of organic compounds by measuring their retention time on the column.

Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.

2'-Deoxyguanosine-5'-diphosphate disodium salt is a marine metabolite that is used as a chemotactic agent for bacteria. It functions by stimulating motility and chemotaxis in marine bacteria. This metabolite is derived from the sulfur oxidation pathway and it has been shown to have genetic regulatory functions in the symbiosis of roseobacters. 2'-Deoxyguanosine-5'-diphosphate disodium salt interacts with the enteric bacteria clade, which may be due to its ability to cycle between sulfur and oxygen environments.

9-(b-D-Arabinofuranosyl)isoguanine is a modified nucleoside that has antiviral activity. It is synthesized by substituting the 2'-hydroxyl group of deoxyribose with an arabinofuranose, which can be phosphorylated to form 9-(b-D-arabinofuranosyl)isoguanine 5'-monophosphate. This novel antiviral agent inhibits the synthesis of viral DNA and RNA, and is effective against a wide range of viruses in vitro. The drug was shown to have anticancer activities in animal models and has been patented for use as a chemotherapeutic agent against leukemia, lymphoma, and other cancers.

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2'-Deoxyguanosine phosphoramidite dimer is a modified nucleoside that is used in the synthesis of DNA. It has anticancer activity and is used as an activator for other nucleotide analogues. This product has CAS number 743-88-2, purity of 99%, and molecular weight of 204.23 g/mol.

2,3'-Anhydro-5'-O-p-anisoylthymidine is a novel nucleoside phosphoramidite that has antiviral properties. It is a modified form of thymidine, which is an important component of DNA and RNA. 2,3'-Anhydro-5'-O-p-anisoylthymidine inhibits the synthesis of viral proteins by incorporation into the viral diphosphate chain. It is also used as an activator for other nucleoside phosphoramidites in oligonucleotide synthesis. This product is suitable for use in applications involving deoxyribonucleosides and nucleosides that require high purity and quality. It can be used in the treatment of cancer and monophosphate forms are used as antiviral agents.

4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite is a novel, modified nucleoside with antiviral activity. It is activated by the addition of a DMT group to its 5' end and has an anticancer effect. The monophosphate form of 4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite has been shown to inhibit viral DNA synthesis in vitro and to be cytotoxic against human cancer cell lines. 4-(2-Cyanoethylthio)-5'-O-DMT- thymidine 3'-CE phosphoramidite is a high quality, high purity product that can be used as a nucleoside or nucleotide in anticancer drugs.

3',5' bis-O-tert-butyldimethylsilyl-2'-O-methyl-5'-methylcytidine is a synthetic nucleoside that is used in the synthesis of DNA and RNA. It can be activated by phosphoramidites for use in oligonucleotide synthesis. This nucleoside has been shown to be an effective activator for DNA polymerase, which is vital for the replication of DNA. 3',5' bis-O-tert-butyldimethylsilyl-2'-O-methyl-5'-methylcytidine has also been shown to inhibit viral replication, including HIV and herpes simplex virus type 1. This compound is a novel monophosphate nucleoside that has been modified with a tert butyl group on the 5' position and an O methyl group on the 2' position. It also contains an additional methyl group at the 5' carbon atom of cytidine

2-Chloro-6-O-methylinosine is a modified nucleoside analog. Its structure is based on inosine and at position 2 a chlorine atom replaces the hydrogen. At position 6, the keto oxygen (normally part of the purine ring) is O-methylated, forming a methoxy group (-OCH₃)

9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-(thiophen-3-yl)purine is a novel monophosphate nucleotide analog, which has been shown to be an activator of anticancer activity. It has been found to inhibit the activity of deoxyribonucleoside kinase, ribonucleotide reductase, and DNA polymerase in vitro. 9-(3'-Deoxy-3'-fluoro-b-D-ribofuranosyl)-6-(thiophen-3-yl)purine is not a substrate for nucleoside phosphorylase and is not incorporated into DNA or RNA. This compound can be used as a precursor for the synthesis of modified nucleotides and phosphoramidites.

2'-Deoxy-5'-O-DMT-uridine 3'-O succinate TEA salt is a modified nucleoside that is an activator for DNA synthesis. It can be used to synthesize oligonucleotides for use in the treatment of cancer and antiviral agents. 2'-Deoxy-5'-O-DMT-uridine 3'-O succinate TEA salt has been shown to inhibit viral replication by inhibiting the function of reverse transcriptase, which is an enzyme that catalyzes the conversion of RNA into DNA. This product has a CAS number, high purity, and high quality.

2'-Deoxycytidine-3'-monophosphate sodium salt is a synthetic phosphoramidite that can be used as an activator to synthesize DNA. It is a nucleoside that has antiviral and anticancer properties, and it is also being investigated for use in the treatment of diseases such as chronic myeloid leukemia. 2'-Deoxycytidine-3'-monophosphate sodium salt is a novel nucleoside with high purity and high quality. It has been shown to inhibit the growth of cancer cells by inhibiting DNA synthesis.

CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.

Acetoacetyl coenzyme A lithium salt is a novel phosphoramidite building block. It's a modified nucleoside that can be used in the synthesis of oligonucleotides and DNA. Acetoacetyl coenzyme A lithium salt has antiviral, anticancer, and antifungal activities.

5'-O-DMT-uridine is an oligodeoxynucleotide that has been conjugated to tetracycline. It is a bioconjugate that can be used for photooxidation of DNA, as well as for the prevention of bacterial efflux. The 5'-O-DMT group can be removed from the uridine by light irradiation or by bioconjugate chemistry, which results in the release of tetracycline and subsequent binding to bacterial ribosomes. This prevents protein synthesis and cell division. The linker can be any cyclic or dehydrating compound.

10mer_3'OH oligonucleotide

2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a modified nucleoside that can be used to synthesize oligonucleotides. The 2'-O group is a protecting group and the 5' hydroxyl group is the site of attachment for the phosphate group. This product is an anticancer, antiviral, and antiretroviral agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo.

This product is a novel nucleoside analog with antiviral, anticancer and antiretroviral activities. It is an activator of ribonucleosides and deoxyribonucleosides. This product is synthesized by the phosphoramidite method. The purity of this product is greater than 98%.

N2-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-guanosine 3'-CE phosphoramidite is a novel, modified ribonucleoside that is used for the synthesis of oligodeoxyribonucleotides. It has been shown to have antiviral and anticancer properties. N2-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-guanosine 3'-CE phosphoramidite is an analog of guanosine and has been shown to be an activator of RNA polymerase II. The compound is synthesized through a high quality, high purity process that produces a monophosphate product with an excellent yield.

N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt is a novel, modified nucleoside analogue that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by competing with natural nucleosides during the process of nucleic acid synthesis. The drug binds to the enzyme ribonucleotide reductase, which is essential for DNA synthesis. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-O succinate TEA salt has been shown to be effective in treating patients with cancer.

2'-Deoxy-5-hydroxymethylcytidine 5'-monophosphate sodium salt (2'-dO-5HmcMP) is a nucleoside analogue that inhibits the activity of reverse transcriptase, an enzyme required for replication of HIV. This compound is phosphorylated in vivo to 2'-dO-5HmcMP monophosphate, which then competitively inhibits the binding of dNTPs to the enzyme and prevents DNA synthesis. 2'-dO-5HmcMP also has anticancer activity and has been shown to inhibit the proliferation of cells in vitro. 2'-dO-5HmcMP has no significant toxicity to humans or other mammals.

5-b-D-Ribofuranosyl-2(1H)-pyridinone is a phosphoramidite that is used in the synthesis of DNA. It is also an antiviral and anticancer agent. 5-b-D-Ribofuranosyl-2(1H)-pyridinone may be modified to include deoxyribonucleosides or ribonucleosides, which are important for DNA synthesis. 5-b-D-Ribofuranosyl-2(1H)-pyridinone is a novel chemical compound with a high purity and quality. 5 b D Ribofuranosyl 2 1 H Pyridinone CAS No 188871 50 3 Activator monophosphate High purity High quality DNA Synthetic Deoxyribonucleosides Novel Modified Ribonuclesides Nucleosides

Pyrimidine-5-carboxamidine hydrochloride (GC) is a guanosine analog that inhibits bacterial growth by binding to the anticodon region of ribosomes. GC has been shown to bind to the replicons of many organisms, including bacteria, and inhibit the formation of mRNA from DNA. This drug also inhibits methyltransferase, which prevents transfer RNA from being modified with methionine. GC may be used in research for eukaryotes and deamination reactions in trna modification.

Cytidine 3’(2’)-monophosphate (CMP) is a biochemical substance that is found in the nucleic acids of cells. It is an equilibrative nucleoside and a precursor to the biosynthesis of uridine and cytidine. CMP is also an intermediate in the synthesis of the coenzyme tetrahydrofolate, which has been shown to inhibit the growth of antibiotic-resistant strains such as Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, and Enterobacter cloacae. Cytidine 3’(2’)-monophosphate can be converted into cytidine by phosphorylation with ATP or by methylation with S-adenosylmethionine. Cytidine 3’(2’)-monophosphate has been shown to have polymerase chain reaction activity

3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine is a novel nucleoside analogue with anticancer activity. 3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine is a modified deoxyribonucleoside monophosphate, which is activated by phosphorylation to the corresponding diphosphate form and then converted to an antiviral agent. 3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine has been shown to have antiviral activity against herpes simplex virus type 1 (HSV1) and Epstein Barr virus (EBV). This compound also inhibits the proliferation of human cancer cells in vitro and in vivo.

2'-Deoxy-3,5-dimethylcytidine is a nucleoside analog that is an activator of the ribonucleotide reductase enzyme. It has been shown to have anticancer properties in vitro and in vivo. 2'-Deoxy-3,5-dimethylcytidine has also been shown to be effective against HIV and herpes virus infections. 2'-Deoxy-3,5-dimethylcytidine is synthesized from deoxyribonucleosides or nucleosides by phosphitylation with phosphoramidites or diphosphates. The CAS number for this product is 198198-29-7.

[(2R,3S,4R,5R)-5-(4-Benzamido-2-oxo-1,2-dihydropyrimidin-1-yl)-3-(benzoyloxy)-4-fluoro-4-methyloxolan-2-yl]methyl benzoate is a novel anticancer drug that selectively inhibits the proliferation of cancer cells. It binds to the DNA and RNA in tumor cells to inhibit nucleotide synthesis and leads to cell death. This product has high purity and is modified for use.

Uridine isomer; found in tRNA

5-Fluoro-2',3'-O-isopropylidenecytidine is a modified nucleoside that has antiviral and anticancer properties. It is a diphosphate of cytidine, with a fluorine atom in the 2'-position and an isopropyl group in the 3'-position. 5-Fluoro-2',3'-O-isopropylidenecytidine is synthesized by reacting 5-fluorocytidine with isopropylamine. This novel compound has been shown to have high quality, high purity, and improved biological activity as compared to other nucleosides.

2'-Deoxyadenosine 3'-O-L-valinyl ester is a novel nucleoside phosphoramidite that is synthesized by activating the 2'-deoxyribose phosphate with an L-valyl chloride. This synthetic nucleoside analog can be used as a substitute for dATP in DNA synthesis and has antiviral as well as anticancer activities.

2',3'-Dideoxyadenosine-5'-monothiophosphate is a nucleoside for use in research applications

2'-Deoxy-5-fluorouridine 5'-diphosphate sodium salt is an antiviral agent that inhibits the synthesis of viral RNA. It is a modified monophosphate nucleotide that is used to treat hepatitis B and C virus infections, as well as AIDS. This drug has been shown to be effective in treating cancer cells, such as leukemia and lymphoma. 2'-Deoxy-5-fluorouridine 5'-diphosphate sodium salt has also been shown to have anticancer properties against colon cancer cells.

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3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine is a nucleoside that acts as an activator and phosphoramidite. The di-O-benzoyl group is used to protect the 2'-hydroxyl group during the synthesis of oligonucleotides. 3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine has been shown to have anticancer activity against human breast cancer cells. It also inhibits the replication of DNA viruses, such as HIV, hepatitis B virus and herpes simplex virus type 1, and is active against influenza A virus. This compound has also been shown to inhibit the production of inflammatory cytokines in vitro.

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N2-Benzyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-guanosine 3'-CE phosphoramidite is a nucleoside which is the phosphate ester of guanosine. It is synthesized from N4-benzoylcytidine 5'-O-DMT phosphoramidite and 2'O,N-bis(tertiarybutyl)dimethylsilylguanosine 3'-Ce phosphoramidite. The product is used in the synthesis of deoxyribonucleosides and as an activator for ribonucleosides. It has anticancer, antiviral, and antimalarial activities.

N4-Acetyl-5'-O-DMT-5-iodocytidine is a novel anticancer and antiviral agent that can be used in the treatment of cancer and HIV. This compound has been modified to inhibit the synthesis of DNA, RNA, and proteins. N4-Acetyl-5'-O-DMT-5-iodocytidine is an activator for phosphoramidites and nucleosides, which are important in the synthesis of DNA. It also enhances the activity of other nucleoside analogues.

2,2'-Anhydrocytidine HCl is a nucleoside for use as a DNA synthesis inhibitor

5'-Azido-2',5'-dideoxy-2'-fluorouridine is a novel nucleoside that is a phosphoramidite. It is an antiviral agent that has been shown to inhibit the synthesis of RNA in cells. This drug also inhibits the growth of cancer cells and can be used for the treatment of leukemia, lymphoma, and myeloma. 5'-Azido-2',5'-dideoxy-2'-fluorouridine has been shown to bind to DNA through its azide group and form a stable covalent bond with the N7 position of guanine. This bond prevents the incorporation of adenosine triphosphate (ATP) into DNA, which prevents DNA transcription and replication.

2-Methylthioadenosine 5-monophosphate (2MTA) is an intermediate in purine metabolism that can be synthesized from adenosine monophosphate and methyl mercaptan. 2MTA inhibits the platelet aggregation by inhibiting the function of the P2Y12 receptor, which is a member of the G protein-coupled receptor family. It has been shown to inhibit tumor growth and tumor vasculature, as well as to induce apoptosis in cancer cells. 2MTA also has antiplatelet activity, which may be due to its ability to inhibit cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2).

5-Azido-2'-deoxycytidine is a high purity, novel, modified, and synthesized nucleoside with anticancer and antiviral properties. It is a diphosphate that is used in the synthesis of DNA as an activator. 5-Azido-2'-deoxycytidine has been shown to inhibit the growth of cancer cells and to be active against influenza virus.

3’-b-C-Methyluridine (3′-b-CMU) is an analog of uridine. It inhibits the activity of viral and bacterial nucleases by attacking the phosphate group. 3′-b-CMU inhibits syncytial formation in cell cultures, which may be due to its ability to inhibit RNA synthesis. This drug has a hydroxyl group that can react with free radicals and may have some inhibitory effect on deoxyribonucleoside triphosphate hydrolysis. 3′-b-CMU is not widely used clinically because it is not readily available, but it is being reinvestigated for use in corynebacterium infections.

3'-Deoxy-5'-O-DMT-3'-fluoro-thymidine (3'DFT) is a nucleoside that can be used as an anticancer drug. It is synthesized by the replacement of the 3'-hydroxyl group with a fluorine atom in 5'-O-DMT-3'-fluoro-thymidine. The synthesis of 3'DFT starts with the reaction of 5'O-(4,4'-dimethoxytrityl)-3'-deoxyuridine and 1,2,4,5-tetraisopropyldiazoacetate to form 5'O-(4,4'-dimethoxytrityl)-3'-deoxythymidine. This is followed by a reduction of the ester group to produce 5'O-(4,4'dimethoxytrityl)-3'F-thymidine. An acetate group is then added to

5'-O-DMT-2,2'-anhydrouridine is a nucleoside that is an activator of RNA polymerase. This compound is novel and can be used for the synthesis of modified oligonucleotides and DNA. 5'-O-DMT-2,2'-anhydrouridine has anticancer properties and can be used in the treatment of cancer. 5'-O-DMT-2,2'-anhydrouridine has been shown to inhibit the growth of cancer cells by binding to DNA and inhibiting the production of RNA.

2-Nicotinamide-2,3,5-tri-O-acetyl-β-D-riboside bromide is a novel antiviral agent that is structurally related to adenosine monophosphate. It has been shown to be active against Herpes Simplex Virus Type 1 (HSV1) and HSV2 in vitro. Its antiviral activity may be due to the inhibition of viral DNA synthesis and RNA transcription.

2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applications

Anti-viral agent; iodinated analog of deoxycytidine

Troxacitabine is a nucleoside analog that inhibits DNA synthesis by selectively blocking the function of DNA polymerase. It has been shown to have potent antitumor activity in mouse tumor models and in a human breast cancer xenograft model. Troxacitabine has also been shown to inhibit the proliferation of renal cell cancer cells and induce apoptosis in these cells, as well as reduce the viability of cancer cells from other tumor types. Troxacitabine has also been shown to have an effect on body mass index and hematologic response, although it is not currently approved for use in humans.

N6-Isopentenyladenosine-5'-monophosphate sodium salt is an adenosine conjugate acid. It is a monomer of polyribonucleotide chain, which is necessary for the formation of ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). N6-Isopentenyladenosine-5'-monophosphate sodium salt is a conjugate base that has the ability to bind to DNA. This binding prevents the formation of a complex with RNA polymerase, thereby inhibiting transcription and replication.

N2-Isobutyryl-N-trityl-morpholino guanine is a synthetic nucleoside analogue. It has been shown to be an activator of ribonucleotide reductase, and it is a potential anticancer agent. N2-Isobutyryl-N-trityl-morpholino guanine has also been shown to inhibit the replication of DNA and RNA viruses. This compound is being studied for its possible use in the treatment of HIV infection, as well as other viral infections that affect the central nervous system.

Glycosylated pyrimidine analog; DNA component

Universal sulfonate donor for in vivo sulfonation by sulfotransferases

Nicotinic acid riboside is a nicotinic acid derivative that has been shown to increase NAD+ levels in cells. Nicotinic acid riboside has been shown to increase the activity of enzymes involved in energy metabolism and transfer reactions, as well as target enzymes such as nicotinamide phosphoribosyltransferase (NAMPT) and its substrate, nicotinamide mononucleotide (NMN). It also increases cellular NAD+ levels by inhibiting the degradative enzyme, nicotinamide phosphoribosyltransferase (NAMPT). Nicotinic acid riboside can be used to treat metabolic disorders such as diabetes mellitus type 2.

5-Fluoro-1-(b-L-ribofuranosyl)-uracil is a triflate that is synthesized by the intramolecular, stereospecific reaction of l-guanosine and l-adenosine. It has been shown to have high yields in its synthesis. 5-Fluoro-1-(b-L-ribofuranosyl)-uracil can be used to produce glycosidations with d-galactose and l-thymidine. This product can also be used for the production of l-[5-(2,4,6-trimethoxybenzoyl)-1Hpyrazol]-3-[(2S,3R)-3-(bromomethyl)pyrrolidin]-2one (PBI), which is an inhibitor of protein kinase C.

Xanthosine 5'-monophosphate disodium salt is a nucleotide that has been shown to react with nitrite in aqueous solution to form xanthosine 5'-monophosphate. The reaction system can be prepared by adding nitrite to a solution of xanthosine 5'-monophosphate disodium salt and deionized water. The crystallization process can be done by adding ethanol dropwise to the reaction system under controlled conditions. Impurities may result from the preparation process, such as sodium chloride, sodium sulfate, and sodium hydroxide.

2',3'-Didehydro-2',3'-dideoxyuridine (DDDU) is a nucleoside analog that inhibits the formation of HIV. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in cell culture, and has been shown to inhibit the production of HIV-1 virions in vitro. 2',3'-Didehydro-2',3'-dideoxyuridine has been shown to bind to the enzyme glycosyltransferase, which is required for HIV-1 replication. DDU also binds to human CD4+ T cells, deflecting them from the HIV-infected target cell. This compound may be useful as an antiviral agent against HIV-1 infection by inhibiting viral replication and infectivity.

5-Methoxy-4’-thiouridine is a monophosphate nucleoside that is synthesized by the phosphorylation of 5-methoxy-4’-thioguanosine. It has antiviral activity, which is due to its ability to inhibit viral DNA polymerase and prevent the production of viral DNA. 5-Methoxy-4’-thiouridine also inhibits the synthesis of deoxyribonucleosides and ribonucleosides, thereby preventing the formation of RNA and DNA. This agent has been shown to be an anticancer agent that can cause cell death by inhibiting protein synthesis.