Antidepressant
Antidepressants are compounds used to treat depressive disorders by altering neurotransmitter levels in the brain. They include various classes such as SSRIs, SNRIs, tricyclics, and MAOIs. Research in this area focuses on understanding the mechanisms of action, efficacy, and side effects of these drugs. At CymitQuimica, we offer a wide range of antidepressant compounds for research purposes, supporting studies in neuroscience and psychopharmacology.
Products of "Antidepressant"
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N-Desmethyl Paroxol Hydrochloride
CAS:Controlled ProductFormula:C12H16FNO·ClHColor and Shape:WhiteMolecular weight:245.72Amitriptyline hydrochloride
CAS:Controlled ProductFormula:C20H23N·ClHColor and Shape:NeatMolecular weight:313.863-(9,10-Ethanoanthracen-9(10H)-yl)prop-2-enal
CAS:Controlled ProductFormula:C19H16OColor and Shape:NeatMolecular weight:260.33Ethyl [3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl]methylcarbamate
CAS:Controlled ProductFormula:C22H25NO2Color and Shape:NeatMolecular weight:335.44Milnacipran Hydrochloride
CAS:Controlled ProductFormula:C15H22N2O·ClHColor and Shape:NeatMolecular weight:282.81Nor Doxepin-d3 Hydrochloride
CAS:Controlled ProductFormula:C182H3H16NO·ClHColor and Shape:NeatMolecular weight:304.83Benzeneethan-α,α,β,β-d4-ol
CAS:Controlled ProductFormula:C8H6D4OColor and Shape:NeatMolecular weight:126.19rac-cis-N-Desmethyl Sertraline Hydrochloride
CAS:Controlled ProductFormula:C16H15Cl2N·ClHColor and Shape:WhiteMolecular weight:328.66rac-cis-2,3-Dichloro Sertraline Hydrochloride
CAS:Formula:C17H17Cl2N·ClHColor and Shape:NeatMolecular weight:342.69052-Chloropyridine-3-carbonitrile (2-Chloronicotinonitrile)
CAS:Controlled ProductFormula:C6H3ClN2Color and Shape:NeatMolecular weight:138.55Amitriptyline hydrochloride 100 µg/mL in Acetonitrile
CAS:Formula:C20H23N·ClHColor and Shape:Single SolutionMolecular weight:313.865-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone Oxime(Fluvoxamine Impurity)
CAS:Controlled ProductApplications Fluvoxamine intermediate. References Kamlet, M., et al.: J. Phys. Chem., 92, 5244 (1988), Terabe, S., et al.: J. Pharm. Biomed. Anal., 10, 705 (1992), Altria, K., et al.: J. Pharm. Biomed. Anal.,18, 807 (1998),Formula:C13H16F3NO2Color and Shape:NeatMolecular weight:257.27Dosulepin Sulfone N-Oxide Hydrochloride (Dosulepin N,S,S-Trioxide Hydrochloride)
Formula:C19H21NO3S·ClHColor and Shape:Neat1-(3-Chlorophenyl)-2-hydroxy-1-propanone
CAS:Controlled ProductFormula:C9H9ClO2Color and Shape:NeatMolecular weight:184.62Fluvoxamine EP Impurity I
CAS:Controlled ProductFormula:C13H16F3NO2Color and Shape:NeatMolecular weight:275.27Bupropion Hydrochloride
CAS:Controlled ProductFormula:C13H18ClNO·ClHColor and Shape:NeatMolecular weight:276.20(S)-Citalopram-d6 Oxalate
CAS:Controlled ProductStability Hygroscopic Applications A labelled inhibitor of serotonin (5-HT) uptake. Antidepressant. References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001), Fish, E.W., et al.: J. Pharmacol. Exp. Ther, 308, 474 (2004),Formula:C202H6H15FN2O·C2H2O4Color and Shape:White To Off-WhiteMolecular weight:420.46Protriptyline-D3.HCl, 0.1mg/ml in Methanol (as free base)
CAS:Controlled ProductFormula:C19D3H18N·HClDosulepin EP Impurity B
CAS:Controlled ProductFormula:C14H10OSColor and Shape:NeatMolecular weight:226.29N-Desmethyl Clomipramine-d3 Hydrochloride
CAS:Controlled ProductApplications A labelled metabolite of Clomipramine. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References McTavish, D., et al.: Drugs, 39, 136 (1990), Chauret, N., et al.: Drug Metab. Dispos., 25, 1130 (1997), Gex-Fabry, M., et al.: Ther. Drug Monit., 22, 701 (2000), Herrera, D., et al.: J. Clin. Pharmacol., 40, 1488 (2000),Formula:C182H3H18ClN2·ClHColor and Shape:Light Beige SolidMolecular weight:340.31Reboxetine Mesylate
CAS:Controlled ProductApplications A selective noradrenaline reuptake inhibitor. Antidepressant. References Cocchiara, G., et al.: Eur. J. Drug. Metab. Pharmacokinet., 16, 231 (1991), Pelliazoni, C., et al.: Biopharm. Drug. Dispos., 17, 623 (1996),Formula:C19H23NO3·CH4O3SColor and Shape:Off White SolidMolecular weight:409.502-Bromo-1-(3-chlorophenyl)propan-1-one (2-Bromo-3'-chloropropiophenone)
CAS:Controlled ProductFormula:C9H8BrClOColor and Shape:NeatMolecular weight:247.52Vilazodone Carboxylic Acid
CAS:Controlled ProductStability Hygroscopic Applications Vilazodone Carboxylic Acid is the carboxylic acid impurity and an intermediate in the preparation of the antidepressant Vilazodone (V265000). References Heinrich, T. et al.: J. Med. Chem., 47, 4684 (2004); Hu, B. et al.: Org. Proc. Res. Dev., 16, 1552 (2012);Formula:C26H26N4O3Color and Shape:NeatMolecular weight:442.51(E)-1-(4-(Trifluoromethyl)phenyl)pentan-1-one Oxime
Controlled ProductApplications (E)-1-(4-(Trifluoromethyl)phenyl)pentan-1-one Oxime is an impurity in the synthesis of Fluvoxamine (F603500), a selective serotonin reuptake inhibitor (SSRI) used as an anti-depressant. Antiobsessional.Formula:C12H14F3NOColor and Shape:NeatMolecular weight:245.241(1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine Hydrochloride
CAS:Formula:C17H19N·ClHR-Mirtazapine
CAS:Controlled ProductApplications R-Mirtazapine is an enantiomer of Mirtazapine (M365000); an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects. References Muth-Selbach, Uta., et al.: Brain Res. Bull., 79(1), 63-68 (2009); Smith, Donald F., et al.: Psychopharmacology, 200(2), 273-279 (2008); Freynhagen, Rainer., et al.: Brain Res. Bull., 69(2), 168-173 (2006)Formula:C17H19N3Color and Shape:NeatMolecular weight:265.355-Methoxy-1-[4-(difluoromethyl)phenyl]-1-pentanone Oxime
CAS:Controlled ProductApplications Defluoro Fluvoxamine intermediate.Formula:C13H17F2NO2Color and Shape:NeatMolecular weight:257.28cis-10-Hydroxy Nortriptyline
CAS:Applications A metabolite of Nortriptyline (N837000). References Callaghan, R., et al.: J. Biol. Chem., 268, 16059 (1993), Dagenais, C., et al.: Biochem. Pharmacol., 67, 269 (2004), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),Formula:C19H21NOColor and Shape:NeatMolecular weight:279.38(R)-(+)-3-Chloro-1-phenyl-1-propanol
CAS:Applications Intermediate in the preparation of (S)-Norfluoxetine References Zhang, P., et al.: Bioorg. Med. Chem. Lett., 18, 6067 (2008), Graves, A., et al.: J. Mol. Biol., 377, 914 (2008), Cashman, J., et al.: Bioorg. Med. Chem., 17, 337 (2009),Formula:C9H11ClOColor and Shape:Off White PowderMolecular weight:170.64Doxepin-D3 Hydrochloride (cis/trans) 0.1 mg/ml in Methanol (as free base)
CAS:Formula:C192H3H18NO·ClHD,L-Venlafaxine, Hydrochloride
CAS:Applications D,L-Venlafaxine is a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant. References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)Formula:C17H27NO2·ClHColor and Shape:WhiteMolecular weight:313.86Venlafaxine N-Oxide
CAS:Controlled ProductApplications Venlafaxine N-Oxide is a prodrug of the antidepressant Venlafaxine ( V119995). References Bickel, M., et al.: Pharmacol. Rev., 325 (1969);Formula:C17H27NO3Color and Shape:NeatMolecular weight:293.40rac N-Desmethyl Venlafaxine
CAS:Applications A metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant. References Kelsey, J., et al.: J. Clin. Psychopharmacol., 16, 21 (1996), Long, C., et al.: J. Anal. Toxicol., 21, 166 (1997), Deecher, D., et al.: J. Pharmacol. Exp. Ther., 318, 657 (2006)Formula:C16H25NO2Color and Shape:Off-White To BeigeMolecular weight:263.38Fluoxetine hydrochloride 100 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C17H18F3NO·ClHColor and Shape:Single SolutionMolecular weight:345.793-(5H-Dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine (Depramine; 10,11-Dehydroimipramine)
CAS:Controlled ProductFormula:C19H22N2Color and Shape:NeatMolecular weight:278.39(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol 3-(4-Methylbenzenesulfonate)
CAS:Formula:C20H24FNO3SPhenelzine Sulfate
CAS:Controlled ProductFormula:C8H12N2·H2O4SColor and Shape:NeatMolecular weight:234.27Paroxetine-D6.maleate, 1mg/ml in Methanol (as free base)
Controlled ProductFormula:C192H6H14FNO3·C4H4O4
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