Antidepressant

Applications Primary metabolite of Tianeptine. References Dresse, A., et al.: J. Clin. Pharmacol., 28, 1115 (1988), Grislain, L., et al.: Drug Metab. Dispos., 18, 804 (1990),

Applications A metabolite of Mirtazapine, α2-adrenergic blocker. References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)

Applications Asenapine (A788000) metabolite. References Lobell, M., et al.: J. Pharm., Sci., 92, 360 (2003), Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Toulmin, A., et al.: J. Med. Chem., 51, 3720 (2008),

Applications Diclofensine is a stimulant; inhibits reuptake of dopamine and noradrenaline, is an effective antidepressant. Diclofensine exhibits significant addictive properties. References Supersaxo, A., et al.: Pharm. Res., 8, 1286 (1991), Nakachi, N., et al.: Eur. J. Pharmacol., 281, 195 (1995), Chankvetadze, B., et al.: J. Pharm. Biomed. Anal., 27, 467 (2001),

Applications S-Mirtazapine is an enantiomer of Mirtazapine (M365000); an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects. References Muth-Selbach, Uta., et al.: Brain Res. Bull., 79(1), 63-68 (2009); Smith, Donald F., et al.: Psychopharmacology, 200(2), 273-279 (2008); Freynhagen, Rainer., et al.: Brain Res. Bull., 69(2), 168-173 (2006)

Applications Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter. References Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),

Applications Fluoxetine (F597100) derivative. A stereoselective inhibitor of serotonin re-uptake and phosphodiesterase. Potential antidepressants References Cashman, J. et al.: Bioorgan Med. Chem. 17, 337 (2009)

Applications Opipramol-d4 Dihydrochloride is a labeled antidepressant; antipsychotic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Maxwell, R.A., et al.: J. Pharm. Exper. Therap., 178, 158 (1970); Tait, A.C., et al.: J. Clin Pharmac., 2, 93 (1975); Rossi, G.V., et al.: Am. J. Pharm., 148, 37 (1976); Hubbard, J.W., et al.: J. Pharm. Sci., 67, 1571 (1978)

Applications The (S)-isomer of Viloxazine (V312440). Antidepressant. References Howe, R., et al.: J. Med. Chem., 19, 1074 (1976), Pinder, R.M., et al.: Drugs, 13, 401 (1977),

Stability Hygroscopic Applications A metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant. References Kugelberg, F.C., et al.: J. Anal. Toxicol., 28, 631 (2004),

Stability Hygroscopic Applications O-Desmethyl Venlafaxine N-Dimer is a dimer impurity of O-Desmethyl Venlafaxine (D296500); a metabolite of Venlafaxine (V120000) which is a selective serotonin noradrenaline reuptake inhibitor (SNRI). Also used as an antidepressant. References Shams, M., et al.: J. Clinic. Pharm. Ther., 31, 493 (2006); Huq, F., et al.: J. Pharmacol. Toxicol., 3, 27 (2008); Isoherranen, N., et al.: Chem. Res. Toxicol., 22, 294 (2009)

Applications Antidepressant. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lehner, H., et al.: Arzneim.-Forsch., 17, 185 (1967), Egli, A., et al.: Anal. Profiles Drug Subs., 9, 181 (1980),

Applications A novel labelled antidepressant distinguished from existing tricyclic and tetracyclic antidepressants by its bicyclic structure. References Hunt, P., et al.: J. Pharm. Pharmacol., 26, 370 (1974), Spyraki, C., et al.: Science, 212, 1167 (1981),

Trimipramine maleate, a tricyclic antidepressant, blocks serotonin and norepinephrine reuptake, boosting their levels and duration.

Applications A labelled metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant. References Kugelberg, F.C., et al.: J. Anal. Toxicol., 28, 631 (2004),

Applications A metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant.

Applications Dendrobine is an alkaloid isolated from Dendrobium nobile and is an antagonist of β-alanine, taurine and of presynaptic inhibition in the frog spinal cord. References Kudo, Y., et. al.: Brit. J. Pharmacol., 78, 709 (1983)

Applications Fluvoxamine impurity.

Impurity Fluoxetine USP Related Compound C Applications A related compound of Fluoxetine (F597100). Fluoxetine USP Related Compound C. References Amstutz, R., et al.: J. Med. Chem., 28, 1760 (1985),

Applications A metabolite of Venlafaxine.