Antidepressant
Antidepressants are compounds used to treat depressive disorders by altering neurotransmitter levels in the brain. They include various classes such as SSRIs, SNRIs, tricyclics, and MAOIs. Research in this area focuses on understanding the mechanisms of action, efficacy, and side effects of these drugs. At CymitQuimica, we offer a wide range of antidepressant compounds for research purposes, supporting studies in neuroscience and psychopharmacology.
Products of "Antidepressant"
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Amitriptyline-D3 Hydrochloride 0.1 mg/ml in Methanol (as free base)
CAS:Controlled ProductFormula:C202H3H20N·ClHa-Μethyl-6-benzofuran Ethanamine Hydrochloride(6-APB Hydrochloride)
CAS:Controlled ProductApplications 6-APB or Benfamine is a chemical of the phenethylamine and amphetamine classes. 6-APB is similar to MDA in that the 3,4-methylenedioxyphenyl ring system has been replaced with a benzofuran ring. 6-APB is also the unsaturated benzofuran derivative of 6-APDB. 6-APB is an intermediate for the preparation of aminoalkylbenzofurans as 5-HT2C agonists used as antiobesity and antidepressant agents. References Ishii, H., et al.: Chem. Pharm. Bull., 40, 1993 (1992)Formula:C11H13NO·ClHColor and Shape:WhiteMolecular weight:211.69Nortriptyline-D3.HCl, 0.1mg/ml in Methanol (as free base)
CAS:Controlled ProductFormula:C192H3H18N·ClHN-(2-Bromoethyl-d4)phthalimide
CAS:Controlled ProductApplications N-(2-Bromoethyl-d4)phthalimide is the labeled analogue of N-(2-Bromoethyl)phthalimide (B683975), a building block that has been used as a reactant for the preparation of β-Cyclodextrin derivatives. N-(2-Bromoethyl-d4)phthalimide is an intermediate in the synthesis of (E)-Fluvoxamine-d4 Maleate (F603503), the labeled analogue of (E)-Fluvoxamine Maleate (F603500), a selective serotonin reuptake inhibitor (SSRI) used as an anti-depressant. Antiobsessional. References Karginov, V.A., et. al.: Bioorg. Med. Chem., 14, 33 (2006); Claassen, V., et al.: Br. J. Pharmacol., 60, 505 (1977); Koran, L.M., et al.: J. Clin. Psychopharmacol., 16, 121 (1996); Ware, M.R., et al.: J. Clin. Psychiatry, 58, Suppl. 5, 15 (1997); Inazu, M., et al.: Neurochem. Int., 39, 39 (2001)Formula:C10D4H4BrNO2Color and Shape:NeatMolecular weight:258.1Clomipramine-D3.HCl, 1mg/ml in Methanol (as free base)
CAS:Controlled ProductFormula:C192H3H20ClN2·ClHHydroxy Bupropion-d6
CAS:Controlled ProductFormula:C13H12D6ClNO2Color and Shape:Off-WhiteMolecular weight:261.78rac trans-Paroxetine-d4 Hydrochloride
CAS:Controlled ProductFormula:C19H17D4ClFNO3Color and Shape:NeatMolecular weight:369.85D,L-O-Desmethyl Venlafaxine
CAS:Applications A metabolite of Venlafaxine (V120000), a selective serotonin noradrenaline reuptake inhibitor (SNRI). Used as an antidepressant. References Shams, M., et al.: J. Clinic. Pharm. Ther., 31, 493 (2006), Huq, F., et al.: J. Pharmacol. Toxicol., 3, 27 (2008), Isoherranen, N., et al.: Chem. Res. Toxicol., 22, 294 (2009),Formula:C16H25NO2Color and Shape:Off-WhiteMolecular weight:263.38N-(2-Succinyl) Fluvoxamine Bis-methyl Ester
Controlled ProductApplications N-(2-Succinyl) Fluvoxamine Bis-methyl Ester is an intermediate in synthesizing N-(2-Succinyl) Fluvoxamine (S688800), a Fluvoxamine impurity. References Wieling, J., et al.: J. Chromatogr., 635, 195 (1993); Hilhorst, M., et al.: J. Pharm. Biomed. Anal., 16, 1251 (1998)Formula:C21H29F3N2O6Color and Shape:NeatMolecular weight:462.463-[(1RS)-5-Bromo-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-1-yl]-N,N-dimethylpropan-1-amine Hydrogen Oxalate
CAS:Formula:C19H21BrFNO·C2H2O4Citalopram-D6.HBr, 0.1mg/ml in Methanol (as free base)
CAS:Controlled ProductFormula:C202H6H15FN2O·BrHNortriptyline-D3 Hydrochloride 0.1 mg/ml in Methanol (as free base)
CAS:Controlled ProductFormula:C192H3H18N·ClHLofepramine Hydrochloride
CAS:Controlled ProductFormula:C26H27ClN2O·ClHColor and Shape:NeatMolecular weight:455.424’-Hydroxy Trazodone
CAS:Applications The main metabolite of Trazodone-HCl (T718500). References Yamato, C., et al.: Xenobiotica, 4, 765 (1974), Hull, M., et al.: Br. Med. J., 309, 378 (1994), Garcia-Pando, A., et al.: J. Clin. Psychiatry, 63, 135 (2002), Kalgutkar, A., et al.: Curr. Drug Metab., 3, 379 (2002), Kalgutkar, A., et al.: Drug Metab. Dispos., 33, 243 (2005),Formula:C19H22ClN5O2Color and Shape:NeatMolecular weight:387.86(3RS)-N-Methyl-3-phenyl-3-[3-(trifluoromethyl)phenoxy]propan-1-amine Hydrochloride
CAS:Formula:C17H18F3NO·ClHS-(-)-Sulpiride
CAS:Controlled ProductApplications Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic. References Pitre, D., et al.: Anal. Profiles Drug Subs., 17, 607 (1988), Wagstaff, A.J., et al.: CNS Drugs, 2, 313 (1994),Formula:C15H23N3O4SColor and Shape:WhiteMolecular weight:341.43Nordeprenyl (>90%)
CAS:Controlled ProductApplications A metabolite of Deprenyl. References Yoshida, T., et al.: Xenobiotica, 17, 957 (1987), Meeker, J., et al.: J. Anal. Toxicol., 14, 330 (1990), Heinonen, E., et al.: Clin. Pharm. Ther., 56, 742 (1994), Szoko, E., et al.: Int. J. Pharm. Adv., 1, 320 (1996),Formula:C12H15NPurity:>90%Color and Shape:NeatMolecular weight:173.25Tianeptine-d12
CAS:Controlled ProductApplications Labelled tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant. References Malen, C., et al.: Experientia, 28, 811 (1972), Safa, A., et al.: J. Biol. Chem., 262, 7884 (1987), Ford, J.M., et al.: Pharmacol. Rev., 42, 155, (1990), Pierre, A., et a.: Cancer Res., 51, 2312 (1991),Formula:C21H13D12ClN2O4SColor and Shape:NeatMolecular weight:449.03Venlafaxine O-desmethyl
CAS:Controlled ProductFormula:C16H25NO2Color and Shape:NeatMolecular weight:263.38N-Desmethyl Asenapine-d4 Hydrochloride
CAS:Controlled ProductApplications Labelled Asenapine (A788000) metabolite. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lobell, M., et al.: J. Pharm., Sci., 92, 360 (2003), Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Toulmin, A., et al.: J. Med. Chem., 51, 3720 (2008),Formula:C16H11D4Cl2NOColor and Shape:NeatMolecular weight:312.23Amitriptyline EP Impurity G (Nortriptyline EP Impurity I)
CAS:Controlled ProductFormula:C15H14OColor and Shape:NeatMolecular weight:210.27Tryptophan EP Impurity A
CAS:Controlled ProductFormula:C24H26N4O4Color and Shape:NeatMolecular weight:434.49Citalopram-d6
CAS:Controlled ProductApplications Labelled Citalopram (C505000), an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant. References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001),Formula:C202H6H15FN2OColor and Shape:Colourless To Light YellowMolecular weight:330.435-(3-Chloropropyl)-5H-dibenz[b,f]azepine
CAS:Controlled ProductFormula:C17H16ClNColor and Shape:NeatMolecular weight:269.77N-Formylfluoxetine
CAS:Controlled ProductApplications N-Formylfluoxetine, is a derivative of Fluoxetine (F597100), a selective serotonin reuptake inhibitor (SSRI). Used as an antidepressant. References Wong, D.T., et al.: Life Sci., 15, 471 (1974), Goldstein, D.J., et al.: Br. J. Psychiat., 166, 660 (1995), Ni, Y.G., et al.: Proc. Nat. Acad. Sci. USA, 94, 2036 (1997)Formula:C18H18F3NO2Color and Shape:NeatMolecular weight:337.34Reboxetine Mesilate
CAS:Controlled ProductFormula:C19H23NO3·CH4O3SColor and Shape:NeatMolecular weight:409.50Bupropion hydrochloride
CAS:Controlled ProductFormula:C13H18ClNO·ClHColor and Shape:NeatMolecular weight:276.20Venlafaxine EP Impurity B (as Hydrochloride)
CAS:Controlled ProductFormula:C14H21NO3·ClHColor and Shape:NeatMolecular weight:287.784-Methylbenzenesulphonic Acid Hydrate
CAS:Controlled ProductFormula:C7H8O3S·H2OColor and Shape:NeatMolecular weight:190.22(3S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine Oxalate (N-Methylduloxetine Oxalate)
CAS:Formula:C19H21NOS·C2H2O41-[(1RS)-2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol Hydrochloride
CAS:Controlled ProductFormula:C15H23NO2·ClHColor and Shape:NeatMolecular weight:285.814-Hydroxy Duloxetine
CAS:Applications A major metabolite of Duloxetine. References Lantz, R.J., et al.: Drug Dispos. Metab., 31, 1142 (2003), Detke, M., et al.: J. Clin Psy., 63, 308 (2002), Bymaster, F.P., et al.: Bioorg. Med., Chem. Lett., 13, 4477 (2003),Formula:C18H19NO2SColor and Shape:NeatMolecular weight:313.41
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