Anthracyclines
Anthracyclines are a class of potent antitumoral antibiotics that are widely used in cancer chemotherapy. These compounds work by intercalating into DNA, thereby disrupting the function of topoisomerase II and preventing the replication of cancer cells. Anthracyclines are particularly effective against a broad range of cancers, including leukemias, lymphomas, and breast cancer. However, their use is often limited by their cardiotoxicity, making research into safer and more effective formulations a key area of focus. At CymitQuimica, we provide a selection of anthracyclines for your research in oncology, drug development, and cancer therapy.
Products of "Anthracyclines"
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Doxorubicinone (Doxorubicin EP Impurity D, Epirubicin EP Impurity A)
CAS:Formula:C21H18O9Color and Shape:Red SolidMolecular weight:414.37Mitoxantrone EP Impurity D HCl
CAS:Formula:C22H26N4O6·HClColor and Shape:Dark Blue SolidMolecular weight:442.48 36.46Doxorubicin-13C-d3 HCl (Daunorubicin EP Impurity D-13C-d3 HCl, Epirubicin EP Impurity C-13C-d3 HCl)
CAS:Formula:C13C22H26D3NO11·HClMolecular weight:547.56 36.45Doxorubicin Impurity 15
CAS:Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.Formula:C31H38BrNO11Purity:Min. 95%Molecular weight:680.54 g/molMitoxantrone EP Impurity C Ditrifluoroacetate
CAS:Formula:C22H27ClN4O6·2C2HF3O2Molecular weight:478.93 2*114.02Epirubicin
CAS:Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.Formula:C27H29NO11Color and Shape:SolidMolecular weight:543.52Doxorubicin Imp B HBr salt
CAS:Doxorubicin Imp B HBr salt is a drug product that is custom synthesized for research and development. It's high purity, analytical, and natural are well suited for pharmacopoeia, drug development, and niche. Doxorubicin Imp B HBr salt has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The CAS No. 148218-14-8 is an impurity standard that can be used in HPLC analysis to determine the purity of Doxorubicin Imp B HBr salt.Formula:C29H34BrNO11BrHPurity:Min. 95%Molecular weight:733.4 g/molMitoxantrone
CAS:Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.Formula:C22H28N4O6Purity:97.97% - 98.74%Color and Shape:Blue PowderMolecular weight:444.48Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurity:100% - 99.93%Color and Shape:SolidMolecular weight:533.95Idarubicin Lactose Adduct Trifluoroacetate (Amadori Rearrangement Product)
Formula:C38H47NO19·C2HF3O2Molecular weight:821.78 114.02Epirubicin hydrochloride
CAS:Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.Formula:C27H30ClNO11Purity:98.13% - 99.79%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.98Ref: TM-T0125
2mg39.00€5mg56.00€10mg88.00€25mg150.00€50mg240.00€100mg324.00€500mg785.00€1mL*10mM (DMSO)73.00€Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurity:99.28% - 99.63%Color and Shape:Almost White SolidMolecular weight:383.379,10-Anhydro-8-desacetyl-8-carboxy Daunorubicin Hydrochloride
Controlled ProductApplications 9,10-Anhydro-8-desacetyl-8-carboxy Daunorubicin is an impurity of Doxorubicin (D558000), an antineoplastic agent.Formula:C26H26ClNO10Purity:>85%Color and Shape:NeatMolecular weight:547.94Mitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Formula:C22H30Cl2N4O6Purity:100% - 99.85%Color and Shape:Blue-Black Solid From Water Ethanol SolidMolecular weight:517.4Doxorubicin HCl (Daunorubicin EP Impurity D HCl, Epirubicin EP Impurity C HCl)
CAS:Formula:C27H29NO11·HClColor and Shape:Red SolidMolecular weight:543.53 36.46Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone
CAS:Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone is a research and development impurity standard for synthesis. It is a synthetic, high purity compound with a CAS number of 89991-52-6. The chemical is not found in nature and does not have any natural metabolites. Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone has been shown to be metabolized by the liver into various metabolites that have been identified through analysis of urine samples. The metabolite of des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone may be used as an analytical standard for HPLC methods.Formula:C18H19N3O5Purity:Min. 95%Molecular weight:357.36 g/molDoxorubicin Dimer Impurity-1
Please enquire for more information about Doxorubicin Dimer Impurity-1 including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C54H56N2O21Purity:Min. 95%Molecular weight:1,069.02 g/molMitoxantrone (2-hydroxyethyl)piperazine impurity
CAS:Mitoxantrone is an anticancer drug that is used to treat various types of cancer. Mitoxantrone is a prodrug, which means it needs to be metabolized by the body to become active. The main metabolic pathway for mitoxantrone involves hydrolysis of the 2-hydroxyethyl piperazine impurity and formation of N-desmethylmitoxantrone, which is a metabolite that has been found to be more potent than the parent compound in inhibiting DNA synthesis. This impurity standard is used as a reference substance for quality control purposes during drug development. Mitoxantrone can also be synthesized with high purity and custom synthesis services are available upon request.Formula:C22H26N4O6Purity:Min. 95%Color and Shape:Brown PowderMolecular weight:442.47 g/mol14-Bromo, 13-Deoxo, 13,13-Dimethoxy Daunorubicin Hydrobromide (>85%)
CAS:Controlled ProductApplications (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione, is the metabolite of Doxorubicin (D558000), which is a neoplasm inhibitor,and an antineoplastic. References Smith, T.H., et al.: J. Med. Chem., 22, 40 (1979); Di Marco, A., et al.: Cancer Chemother. Rep., (part 1), 53, 33 (1969), Mihich, E. and Ehrke, M.J.: Transplant. Proc., 16, 499 (1984),Formula:C29H34BrNO11·BrHPurity:>85%Color and Shape:NeatMolecular weight:733.40
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